Kinome screen of ferroptosis reveals a novel role of ATM in regulating iron metabolism
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Kinome screen of ferroptosis reveals a novel role of ATM in regulating iron metabolism
Authors
Keywords
-
Journal
CELL DEATH AND DIFFERENTIATION
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-07-18
DOI
10.1038/s41418-019-0393-7
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- p53 Suppresses Metabolic Stress-Induced Ferroptosis in Cancer Cells
- (2018) Amy Tarangelo et al. Cell Reports
- The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models
- (2018) Stephen T. Durant et al. Science Advances
- BAP1 links metabolic regulation of ferroptosis to tumour suppression
- (2018) Yilei Zhang et al. NATURE CELL BIOLOGY
- Cystine addiction of triple-negative breast cancer associated with EMT augmented death signaling
- (2017) X Tang et al. ONCOGENE
- The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity
- (2017) Yangchun Xie et al. Cell Reports
- The Roles of NRF2 in Modulating Cellular Iron Homeostasis
- (2017) Michael John Kerins et al. ANTIOXIDANTS & REDOX SIGNALING
- Cystine Deprivation Triggers Programmed Necrosis in VHL-Deficient Renal Cell Carcinomas
- (2016) Xiaohu Tang et al. CANCER RESEARCH
- Ferroptosis: process and function
- (2016) Y Xie et al. CELL DEATH AND DIFFERENTIATION
- Ferroptosis is an autophagic cell death process
- (2016) Minghui Gao et al. CELL RESEARCH
- ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition
- (2016) Sebastian Doll et al. Nature Chemical Biology
- Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis
- (2016) Kenichi Shimada et al. Nature Chemical Biology
- ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia
- (2016) Mark A. Gregory et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ironing out how p53 regulates ferroptosis
- (2016) Maureen E. Murphy PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In Search for Symbolic Qualities of Iron: The Metal of Life
- (2016) Zvi Ioav Cabantchik Frontiers in Pharmacology
- Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation
- (2015) M Hayano et al. CELL DEATH AND DIFFERENTIATION
- Disordered signaling governing ferroportin transcription favors breast cancer growth
- (2015) Yue Chen et al. CELLULAR SIGNALLING
- Ferroptosis as a p53-mediated activity during tumour suppression
- (2015) Le Jiang et al. NATURE
- Ferritin-Mediated Iron Sequestration Stabilizes Hypoxia-Inducible Factor-1α upon LPS Activation in the Presence of Ample Oxygen
- (2015) Isabel Siegert et al. Cell Reports
- Comprehensive Profiling of Amino Acid Response Uncovers Unique Methionine-Deprived Response Dependent on Intact Creatine Biosynthesis
- (2015) Xiaohu Tang et al. PLoS Genetics
- ATM regulation of IL-8 links oxidative stress to cancer cell migration and invasion
- (2015) Wei-Ta Chen et al. eLife
- Regulation of Ferroptotic Cancer Cell Death by GPX4
- (2014) Wan Seok Yang et al. CELL
- ATM regulates cell fate choice upon p53 activation by modulating mitochondrial turnover and ROS levels
- (2014) Kelly D Sullivan et al. CELL CYCLE
- ROS-dependent activation of JNK converts p53 into an efficient inhibitor of oncogenes leading to robust apoptosis
- (2014) Y Shi et al. CELL DEATH AND DIFFERENTIATION
- TAK1 kinase switches cell fate from apoptosis to necrosis following TNF stimulation
- (2014) Sho Morioka et al. JOURNAL OF CELL BIOLOGY
- Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models
- (2014) Rachid Skouta et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
- (2014) Jose Pedro Friedmann Angeli et al. NATURE CELL BIOLOGY
- STRING v10: protein–protein interaction networks, integrated over the tree of life
- (2014) Damian Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- Gene Expression Correlations in Human Cancer Cell Lines Define Molecular Interaction Networks for Epithelial Phenotype
- (2014) Kurt W. Kohn et al. PLoS One
- Synchronized renal tubular cell death involves ferroptosis
- (2014) Andreas Linkermann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cellular protection using Flt3 and PI3Kα inhibitors demonstrates multiple mechanisms of oxidative glutamate toxicity
- (2014) Yunyi Kang et al. Nature Communications
- Pharmacological ascorbate and ionizing radiation (IR) increase labile iron in pancreatic cancer
- (2013) Justin C. Moser et al. Redox Biology
- The taste of heavy metals: Gene regulation by MTF-1
- (2012) Viola Günther et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
- (2012) Scott J. Dixon et al. CELL
- Pathological neoangiogenesis depends on oxidative stress regulation by ATM
- (2012) Yuji Okuno et al. NATURE MEDICINE
- STRING v9.1: protein-protein interaction networks, with increased coverage and integration
- (2012) Andrea Franceschini et al. NUCLEIC ACIDS RESEARCH
- Autophagy and reactive oxygen species modulate cytotoxicity induced by suppression of ATM kinase activity in head and neck cancer cells
- (2012) Chang-Shen Lin et al. ORAL ONCOLOGY
- Iron loading and oxidative stress in the Atm−/− mouse liver
- (2011) Cameron J. McDonald et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- ATM Is a Redox Sensor Linking Genome Stability and Carbon Metabolism
- (2011) A. Kruger et al. Science Signaling
- Chelation of lysosomal iron protects against ionizing radiation
- (2010) Carsten Berndt et al. BIOCHEMICAL JOURNAL
- Induction of FPN1 transcription by MTF-1 reveals a role for ferroportin in transition metal efflux
- (2010) M.-B. Troadec et al. BLOOD
- Mechanism of p53 stabilization by ATM after DNA damage
- (2010) Qian Cheng et al. CELL CYCLE
- 12/15-lipoxygenase-derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases
- (2010) M. Conrad et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Iron release from ferritin induced by light and ionizing radiation
- (2010) Marian Wolszczak et al. RESEARCH ON CHEMICAL INTERMEDIATES
- ATM Activation by Oxidative Stress
- (2010) Z. Guo et al. SCIENCE
- Divalent metal-dependent regulation of hepcidin expression by MTF-1
- (2009) Sara Balesaria et al. FEBS LETTERS
- Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites
- (2009) Sairei So et al. JOURNAL OF CELL BIOLOGY
- Topoisomerase I levels in the NCI-60 cancer cell line panel determined by validated ELISA and microarray analysis and correlation with indenoisoquinoline sensitivity
- (2009) T. D. Pfister et al. MOLECULAR CANCER THERAPEUTICS
- Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion
- (2009) S. E. Golding et al. MOLECULAR CANCER THERAPEUTICS
- Synthetic Lethal Screening Identifies Compounds Activating Iron-Dependent, Nonapoptotic Cell Death in Oncogenic-RAS-Harboring Cancer Cells
- (2008) Wan Seok Yang et al. CHEMISTRY & BIOLOGY
- Overexpression of metal-responsive transcription factor (MTF-1) in Drosophila melanogaster ameliorates life-span reductions associated with oxidative stress and metal toxicity
- (2008) Sepehr Bahadorani et al. NEUROBIOLOGY OF AGING
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now