ATM regulates cell fate choice upon p53 activation by modulating mitochondrial turnover and ROS levels

Recent discoveries in the cycling, growing and aging of the p53 field

(2016) James A. McCubrey et al.   Aging-US

Selective turnover of p62/A170/SQSTM1 by autophagy

(2014) Yoshinobu Ichimura et al.   Autophagy

ROS-dependent activation of JNK converts p53 into an efficient inhibitor of oncogenes leading to robust apoptosis

(2014) Y Shi et al.   CELL DEATH AND DIFFERENTIATION

The ATM protein kinase: regulating the cellular response to genotoxic stress and more

(2013) Yosef Shiloh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulation of autophagy by stress-responsive transcription factors

(2013) Federico Pietrocola et al.   SEMINARS IN CANCER BIOLOGY

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

A DR4:tBID axis drives the p53 apoptotic response by promoting oligomerization of poised BAX

(2012) Ryan E Henry et al.   EMBO JOURNAL

Microtubule-associated Protein 1 Light Chain 3 (LC3) Interacts with Bnip3 Protein to Selectively Remove Endoplasmic Reticulum and Mitochondria via Autophagy

(2012) Rita A. Hanna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATM and MET kinases are synthetic lethal with nongenotoxic activation of p53

(2012) Kelly D Sullivan et al.   Nature Chemical Biology

Autophagy and reactive oxygen species modulate cytotoxicity induced by suppression of ATM kinase activity in head and neck cancer cells

(2012) Chang-Shen Lin et al.   ORAL ONCOLOGY

Absence of Tumor Suppressor Tumor Protein 53-Induced Nuclear Protein 1 (TP53INP1) Sensitizes Mouse Thymocytes and Embryonic Fibroblasts to Redox-Driven Apoptosis

(2011) Prudence N'guessan et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial dysfunction in ataxia-telangiectasia

(2011) Y. A. Valentin-Vega et al.   BLOOD

Bnip3 impairs mitochondrial bioenergetics and stimulates mitochondrial turnover

(2011) S Rikka et al.   CELL DEATH AND DIFFERENTIATION

Weak p53 permits senescence during cell cycle arrest

(2010) Olga V. Leontieva et al.   CELL CYCLE

ATM- and NEMO-Dependent ELKS Ubiquitination Coordinates TAK1-Mediated IKK Activation in Response to Genotoxic Stress

(2010) Zhao-Hui Wu et al.   MOLECULAR CELL

Paradoxical suppression of cellular senescence by p53

(2010) Z. N. Demidenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS

(2010) A. Alexander et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATM Activation by Oxidative Stress

(2010) Z. Guo et al.   SCIENCE

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Hypoxia signals autophagy in tumor cells via AMPK activity, independent of HIF-1, BNIP3 and BNIP3L

(2008) I Papandreou et al.   CELL DEATH AND DIFFERENTIATION

Regulation of autophagy by cytoplasmic p53

(2008) Ezgi Tasdemir et al.   NATURE CELL BIOLOGY