A metabolic perspective on CSF-mediated neurodegeneration in multiple sclerosis

Body Mass Index in Multiple Sclerosis modulates ceramide-induced DNA methylation and disease course

(2019) Kamilah Castro et al.   EBioMedicine

Emerging drugs for primary progressive multiple sclerosis

(2018) Ram Narendra Narayan et al.   EXPERT OPINION ON EMERGING DRUGS

Mitochondrial dysfunction and axon degeneration in progressive multiple sclerosis

(2018) Graham Campbell et al.   FEBS LETTERS

Assessment of suitable reference genes for RT–qPCR studies in chronic rhinosinusitis

(2018) Tsuguhisa Nakayama et al.   Scientific Reports

Multiple sclerosis: Serum-derived exosomes express myelin proteins

(2017) Grazyna Galazka et al.   Multiple Sclerosis Journal

Mitostasis in Neurons: Maintaining Mitochondria in an Extended Cellular Architecture

(2017) Thomas Misgeld et al.   NEURON

Mitochondrial elongation-mediated glucose metabolism reprogramming is essential for tumour cell survival during energy stress

(2017) J Li et al.   ONCOGENE

Bioenergetic Failure in Rat Oligodendrocyte Progenitor Cells Treated with Cerebrospinal Fluid Derived from Multiple Sclerosis Patients

(2017) Deepali Mathur et al.   Frontiers in Cellular Neuroscience

Multiple sclerosis: Serum-derived exosomes express myelin proteins

(2017) Grazyna Galazka et al.   Multiple Sclerosis Journal

The topograpy of demyelination and neurodegeneration in the multiple sclerosis brain

(2016) Lukas Haider et al.   BRAIN

Primary progressive multiple sclerosis: current therapeutic strategies and future perspectives

(2016) Alberto Gajofatto et al.   Expert Review of Neurotherapeutics

Metabolic regulation of mitochondrial dynamics

(2016) Prashant Mishra et al.   JOURNAL OF CELL BIOLOGY

Therapeutic Advances and Future Prospects in Progressive Forms of Multiple Sclerosis

(2016) Afsaneh Shirani et al.   Neurotherapeutics

Mitochondrial Dynamics and Metabolic Regulation

(2016) Timothy Wai et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Primary progressive multiple sclerosis: current therapeutic strategies and future perspectives

(2016) Alberto Gajofatto et al.   Expert Review of Neurotherapeutics

Mitochondrial dysfunction is an important cause of neurological deficits in an inflammatory model of multiple sclerosis

(2016) Mona Sadeghian et al.   Scientific Reports

Calcineurin Links Mitochondrial Elongation with Energy Metabolism

(2015) Paul T. Pfluger et al.   Cell Metabolism

Stage-specific reference genes significant for quantitative PCR during mouse retinal development

(2015) Hiroko Adachi et al.   GENES TO CELLS

An integrated metabolomics approach for the research of new cerebrospinal fluid biomarkers of multiple sclerosis

(2015) Damiana Pieragostino et al.   Molecular BioSystems

Cerebrospinal fluid ceramides from patients with multiple sclerosis impair neuronal bioenergetics

(2014) Oscar G. Vidaurre et al.   BRAIN

Sphingolipids: Important Players in Multiple Sclerosis

(2014) Ramona Halmer et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The validation of housekeeping genes as a reference in quantitative Real Time PCR analysis

(2014) Justyna Jarczak et al.   GENE

Cellular distribution of glucose and monocarboxylate transporters in human brain white matter and multiple sclerosis lesions

(2014) Philip G. Nijland et al.   GLIA

Hexosylceramides as intrathecal markers of worsening disability in multiple sclerosis

(2014) Antonio Checa et al.   Multiple Sclerosis Journal

Defining the clinical course of multiple sclerosis: The 2013 revisions

(2014) F. D. Lublin et al.   NEUROLOGY

Pervasive Axonal Transport Deficits in Multiple Sclerosis Models

(2014) Catherine Diamante Sorbara et al.   NEURON

Mitochondrial Complex Enzyme Activities and Cytochrome c Expression Changes in Multiple Sclerosis

(2013) Pedro Iñarrea et al.   MOLECULAR NEUROBIOLOGY

Reduced expression of PGC-1α partly underlies mitochondrial changes and correlates with neuronal loss in multiple sclerosis cortex

(2012) Maarten E. Witte et al.   ACTA NEUROPATHOLOGICA

Bioenergetic role of mitochondrial fusion and fission

(2012) Benedikt Westermann   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury

(2012) Marie T. Fischer et al.   BRAIN

Biomarkers of mitochondrial content in skeletal muscle of healthy young human subjects

(2012) Steen Larsen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Will the real multiple sclerosis please stand up?

(2012) Peter K. Stys et al.   NATURE REVIEWS NEUROSCIENCE

Selection of Suitable Housekeeping Genes for Real-Time Quantitative PCR in CD4+ Lymphocytes from Asthmatics with or without Depression

(2012) Ting Wang et al.   PLoS One

Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria

(2011) Chris H. Polman et al.   ANNALS OF NEUROLOGY

Analysis of the mitochondrial proteome in multiple sclerosis cortex

(2011) Laurie Broadwater et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Oxidative damage in multiple sclerosis lesions

(2011) L. Haider et al.   BRAIN

Essential amino acids and glutamine regulate induction of mitochondrial elongation during autophagy

(2011) Ligia C. Gomes et al.   CELL CYCLE

Selection of reference genes for gene expression studies in rats

(2011) Roberto Martínez-Beamonte et al.   JOURNAL OF BIOTECHNOLOGY

During autophagy mitochondria elongate, are spared from degradation and sustain cell viability

(2011) Ligia C. Gomes et al.   NATURE CELL BIOLOGY

A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis

(2011) Ivana Nikić et al.   NATURE MEDICINE

Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation

(2011) A. S. Rambold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial DNA deletions and neurodegeneration in multiple sclerosis

(2010) Graham R. Campbell et al.   ANNALS OF NEUROLOGY

Brain tissue sodium concentration in multiple sclerosis: a sodium imaging study at 3 tesla

(2010) M. Inglese et al.   BRAIN

Cerebrospinal fluid ATP metabolites in multiple sclerosis

(2010) G. Lazzarino et al.   Multiple Sclerosis Journal

Sphingolipids in Multiple Sclerosis

(2010) Arundhati Jana et al.   NEUROMOLECULAR MEDICINE

Mitochondrial changes within axons in multiple sclerosis

(2009) D. J. Mahad et al.   BRAIN

Impaired regulation of electron transport chain subunit genes by nuclear respiratory factor 2 in multiple sclerosis

(2009) Ashish Pandit et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Virtual hypoxia and chronic necrosis of demyelinated axons in multiple sclerosis

(2009) Bruce D Trapp et al.   LANCET NEUROLOGY

HDAC1 nuclear export induced by pathological conditions is essential for the onset of axonal damage

(2009) Jin Young Kim et al.   NATURE NEUROSCIENCE

A defect of sphingolipid metabolism modifies the properties of normal appearing white matter in multiple sclerosis

(2008) David Wheeler et al.   BRAIN

Mitochondrial defects in acute multiple sclerosis lesions

(2008) Don Mahad et al.   BRAIN

Natural history of multiple sclerosis in a population-based cohort

(2008) M. Debouverie et al.   EUROPEAN JOURNAL OF NEUROLOGY

Increase in mitochondrial density within axons and supporting cells in response to demyelination in thePlp1mouse model

(2008) Vanessa Hogan et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Cerebrospinal fluid evidence of increased extra-mitochondrial glucose metabolism implicates mitochondrial dysfunction in multiple sclerosis disease progression

(2008) William T. Regenold et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES