Primary progressive multiple sclerosis: current therapeutic strategies and future perspectives

Pharmacokinetics and pharmacodynamics of MD1003 (high-dose biotin) in the treatment of progressive multiple sclerosis

(2016) Laure Peyro Saint Paul et al.   Expert Opinion on Drug Metabolism & Toxicology

Oral fingolimod in primary progressive multiple sclerosis (INFORMS): a phase 3, randomised, double-blind, placebo-controlled trial

(2016) Fred Lublin et al.   LANCET

Therapeutic Advances and Future Prospects in Progressive Forms of Multiple Sclerosis

(2016) Afsaneh Shirani et al.   Neurotherapeutics

Effect of Multiple Sclerosis Disease-Modifying Therapies on B Cells and Humoral Immunity

(2016) Erin E. Longbrake et al.   JAMA Neurology

Progressive multiple sclerosis

(2015) Daniel Ontaneda et al.   CURRENT OPINION IN NEUROLOGY

Clinical trials in progressive multiple sclerosis: lessons learned and future perspectives

(2015) Daniel Ontaneda et al.   LANCET NEUROLOGY

Exploring the origins of grey matter damage in multiple sclerosis

(2015) Massimiliano Calabrese et al.   NATURE REVIEWS NEUROSCIENCE

Concise Review: Modeling Multiple Sclerosis With Stem Cell Biological Platforms: Toward Functional Validation of Cellular and Molecular Phenotypes in Inflammation-Induced Neurodegeneration

(2015) Joshua C. Orack et al.   Stem Cells Translational Medicine

High doses of biotin in chronic progressive multiple sclerosis: A pilot study

(2015) Frédéric Sedel et al.   Multiple Sclerosis and Related Disorders

Remyelination Therapy in Multiple Sclerosis

(2015) Danielle E. Harlow et al.   Frontiers in Neurology

A randomized placebo-controlled phase III trial of oral laquinimod for multiple sclerosis

(2014) T. L. Vollmer et al.   JOURNAL OF NEUROLOGY

Defining the clinical course of multiple sclerosis: The 2013 revisions

(2014) F. D. Lublin et al.   NEUROLOGY

Clinical, MRI, and CSF Markers of Disability Progression in Multiple Sclerosis

(2013) Alberto Gajofatto et al.   DISEASE MARKERS

Placebo-controlled trial of oral laquinimod in multiple sclerosis: MRI evidence of an effect on brain tissue damage

(2013) M. Filippi et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Effect of dronabinol on progression in progressive multiple sclerosis (CUPID): a randomised, placebo-controlled trial

(2013) John Zajicek et al.   LANCET NEUROLOGY

Masitinib treatment in patients with progressive multiple sclerosis: a randomized pilot study

(2012) Patrick Vermersch et al.   BMC Neurology

Meningeal inflammation plays a role in the pathology of primary progressive multiple sclerosis

(2012) Sung R. Choi et al.   BRAIN

Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study

(2012) Peter Connick et al.   LANCET NEUROLOGY

T Cell Vaccination Benefits Relapsing Progressive Multiple Sclerosis Patients: A Randomized, Double-Blind Clinical Trial

(2012) Dimitrios Karussis et al.   PLoS One

A phase III study evaluating the efficacy and safety of MBP8298 in secondary progressive MS

(2011) M. S. Freedman et al.   NEUROLOGY

Review: The architecture of inflammatory demyelinating lesions: implications for studies on pathogenesis

(2011) H. Lassmann   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Mechanism of Action of Oral Fingolimod (FTY720) in Multiple Sclerosis

(2010) Jerold Chun et al.   CLINICAL NEUROPHARMACOLOGY

PAW25 A single-centre, pilot, randomised controlled trial of recombinant human erythropoietin in primary progressive multiple sclerosis

(2010) I. Karpha et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

New perspectives in the natural history of multiple sclerosis

(2010) H. Tremlett et al.   NEUROLOGY

Rituximab in patients with primary progressive multiple sclerosis: Results of a randomized double-blind placebo-controlled multicenter trial

(2009) Kathleen Hawker et al.   ANNALS OF NEUROLOGY

A single-center, randomized, double-blind, placebo-controlled study of interferon beta-1b on primary progressive and transitional multiple sclerosis

(2009) X. Montalban et al.   Multiple Sclerosis Journal

Azathioprine in Multiple Sclerosis

(2008) Paolo Invernizz et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Responsiveness and predictive value of EDSS and MSFC in primary progressive MS

(2008) J. J. Kragt et al.   NEUROLOGY