Chemoenzymatic Platform for Synthesis of Chiral Organofluorines Based on Type II Aldolases

Nucleophile Promiscuity of Engineered Class II Pyruvate Aldolase YfaU from E. Coli

(2018) Karel Hernández et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic enantioselective aldol reactions

(2018) Yasuhiro Yamashita et al.   CHEMICAL SOCIETY REVIEWS

Expanding the reaction space of aldolases using hydroxypyruvate as a nucleophilic substrate

(2017) Véronique de Berardinis et al.   GREEN CHEMISTRY

Combining Aldolases and Transaminases for the Synthesis of 2-Amino-4-hydroxybutanoic Acid

(2017) Karel Hernandez et al.   ACS Catalysis

An Enantio- and Diastereoselective Chemoenzymatic Synthesis of α-Fluoro β-Hydroxy Carboxylic Esters

(2016) James K. Howard et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective aldol reactions with masked fluoroacetates

(2016) Jakub Saadi et al.   Nature Chemistry

Evaluation of fluoropyruvate as nucleophile in reactions catalysed by N-acetyl neuraminic acid lyase variants: scope, limitations and stereoselectivity

(2016) Jennifer Stockwell et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Mechanism-based inhibition of an aldolase at high concentrations of its natural substrate acetaldehyde: structural insights and protective strategies

(2016) Markus Dick et al.   Chemical Science

The chemoenzymatic synthesis of clofarabine and related 2′-deoxyfluoroarabinosyl nucleosides: the electronic and stereochemical factors determining substrate recognition byE. colinucleoside phosphorylases

(2014) Ilja V Fateev et al.   Beilstein Journal of Organic Chemistry

Advances in Catalytic Enantioselective Fluorination, Mono-, Di-, and Trifluoromethylation, and Trifluoromethylthiolation Reactions

(2014) Xiaoyu Yang et al.   CHEMICAL REVIEWS

Introduction of Fluorine and Fluorine-Containing Functional Groups

(2013) Theresa Liang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biocatalytic Methods for CC Bond Formation

(2013) Kateryna Fesko et al.   ChemCatChem

Expanding the Fluorine Chemistry of Living Systems Using Engineered Polyketide Synthase Pathways

(2013) M. C. Walker et al.   SCIENCE

Crystal Structure of Reaction Intermediates in Pyruvate Class II Aldolase

(2012) Mathieu Coincon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Asymmetric synthesis of (R)-3-fluoroalanine from 3-fluoropyruvate using omega-transaminase

(2011) Han-Seop Bea et al.   BIOTECHNOLOGY AND BIOPROCESS ENGINEERING

C−C Bond-Forming Lyases in Organic Synthesis

(2011) Margarita Brovetto et al.   CHEMICAL REVIEWS

Organic fluorine compounds: a great opportunity for enhanced materials properties

(2011) Ricarda Berger et al.   CHEMICAL SOCIETY REVIEWS

Comparison of Two Metal-Dependent Pyruvate Aldolases Related by Convergent Evolution: Substrate Specificity, Kinetic Mechanism, and Substrate Channeling

(2010) Weijun Wang et al.   BIOCHEMISTRY

The direct catalytic asymmetric aldol reaction

(2010) Barry M. Trost et al.   CHEMICAL SOCIETY REVIEWS

Purification and Gene Cloning of  -Methylserine Aldolase from Ralstonia sp. Strain AJ110405 and Application of the Enzyme in the Synthesis of  -Methyl-L-Serine

(2008) H. Nozaki et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Crystal Structure and Functional Assignment of YfaU, a Metal Ion Dependent Class II Aldolase fromEscherichia coliK12†‡

(2008) Dean Rea et al.   BIOCHEMISTRY

Eukaryotic and Bacterial Gene Clusters Related to an Alternative Pathway of Nonphosphorylated L-Rhamnose Metabolism

(2008) Seiya Watanabe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS