Expanding the reaction space of aldolases using hydroxypyruvate as a nucleophilic substrate

Characterization of a Novel d-Glycero-d-talo-oct-2-ulosonic acid-substituted Lipid A Moiety in the Lipopolysaccharide Produced by the Acetic Acid BacteriumAcetobacter pasteurianusNBRC 3283

(2016) Masahito Hashimoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Minimalist Protein Engineering of an Aldolase Provokes Unprecedented Substrate Promiscuity

(2016) Deniz Güclü et al.   ACS Catalysis

Chemistry of Pyruvate Enolates:anti-Selective Direct Aldol Reactions of Pyruvate Ester with Sugar Aldehydes Promoted by a Dinuclear Zinc Catalyst

(2015) Marta A. Molenda et al.   ADVANCED SYNTHESIS & CATALYSIS

Genome Mining for Innovative Biocatalysts: New Dihydroxyacetone Aldolases for the Chemist’s Toolbox

(2015) Christine Guérard-Hélaine et al.   ChemCatChem

AuPt Alloy on TiO2: A Selective and Durable Catalyst forl-Sorbose Oxidation to 2-Keto-Gulonic Acid

(2015) Carine E. Chan-Thaw et al.   ChemSusChem

Chemical constituents from Chorisia chodatii flowers and their biological activities

(2015) John Refaat et al.   MEDICINAL CHEMISTRY RESEARCH

Recent advances in biocatalyst discovery, development and applications

(2014) Guang Yang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis of α-d-glucosyl substituted methyl glycosides of 3-deoxy-α-d-manno- and d-glycero-α-d-talo-oct-2-ulosonic acid (Kdo/Ko) corresponding to inner core fragments of Acinetobacter lipopolysaccharide

(2014) Barbara Pokorny et al.   CARBOHYDRATE RESEARCH

Strategies for the discovery and engineering of enzymes for biocatalysis

(2013) Timo Davids et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Discovery of new enzymes and metabolic pathways by using structure and genome context

(2013) Suwen Zhao et al.   NATURE

Revealing the hidden functional diversity of an enzyme family

(2013) Karine Bastard et al.   Nature Chemical Biology

Biocatalytic retrosynthesis

(2013) Nicholas J Turner et al.   Nature Chemical Biology

Stereoselective strategy for the synthesis of (+)-polyoxamic acid and some polyhydroxylated pyrrolidines

(2013) Macha Lingamurthy et al.   TETRAHEDRON LETTERS

Recent Developments in Enzymatic Asymmetric CC Bond Formation

(2012) Michael Müller   ADVANCED SYNTHESIS & CATALYSIS

Direct Aldol Reaction of Pyruvic Derivatives: Catalytic Attempt To Synthesize Ulosonic Acids

(2012) Osama El-Sepelgy et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Oxidation of carbohydrates of biological importance by the aquachromium(IV) ion

(2012) Juan Carlos González et al.   POLYHEDRON

Enantioselective organocatalytic aldol reaction using small organic molecules

(2012) Vishnumaya Bisai et al.   TETRAHEDRON

Current Trends in Asymmetric Synthesis with Aldolases

(2011) Pere Clapés et al.   ADVANCED SYNTHESIS & CATALYSIS

C−C Bond-Forming Lyases in Organic Synthesis

(2011) Margarita Brovetto et al.   CHEMICAL REVIEWS

Organocatalytic synthesis of carbohydrates

(2011) Jacek Mlynarski et al.   CHEMICAL SOCIETY REVIEWS

Broadening Deoxysugar Glycodiversity: Natural and Engineered Transaldolases Unlock a Complementary Substrate Space

(2011) Madhura Rale et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rational Design of Stereoselectivity in the Class II Pyruvate Aldolase BphI

(2011) Perrin Baker et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Comparison of Two Metal-Dependent Pyruvate Aldolases Related by Convergent Evolution: Substrate Specificity, Kinetic Mechanism, and Substrate Channeling

(2010) Weijun Wang et al.   BIOCHEMISTRY

Recent progress in stereoselective synthesis with aldolases

(2010) Pere Clapés et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Structural and Kinetic Characterization of 4-Hydroxy-4-methyl-2-oxoglutarate/4-Carboxy-4-hydroxy-2-oxoadipate Aldolase, a Protocatechuate Degradation Enzyme Evolutionarily Convergent with the HpaI and DmpG Pyruvate Aldolases

(2010) Weijun Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Enantioselective Synthesis of (+)-Polyoxamic Acid via Phase-Transfer Catalytic Conjugate Addition and Asymmetric Dihydroxylation

(2010) Yeon-Ju Lee et al.   JOURNAL OF ORGANIC CHEMISTRY

Rational assignment of key motifs for function guides in silico enzyme identification

(2010) Matthias Höhne et al.   Nature Chemical Biology

Chemoenzymatic synthesis of differentially protected 3-deoxysugars

(2010) Dennis G. Gillingham et al.   Nature Chemistry

Dioxygenases in Burkholderia ambifaria and Yersinia pestis that hydroxylate the outer Kdo unit of lipopolysaccharide

(2010) H. S. Chung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Asymmetric Self- and Cross-Aldol Reactions of Glycolaldehyde Catalyzed by D-Fructose-6-phosphate Aldolase

(2009) Xavier Garrabou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Directed evolution of aldolases for exploitation in synthetic organic chemistry

(2008) Amanda Bolt et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Crystal Structure and Functional Assignment of YfaU, a Metal Ion Dependent Class II Aldolase fromEscherichia coliK12†‡

(2008) Dean Rea et al.   BIOCHEMISTRY

Evolution of Enzymatic Activities in the Enolase Superfamily:l-Rhamnonate Dehydratase†‡

(2008) John F. Rakus et al.   BIOCHEMISTRY

The role of a conserved histidine residue in a pyruvate-specific Class II aldolase

(2008) Weijun Wang et al.   FEBS LETTERS