Oxidative stress pathways in pancreatic beta cells and insulin sensitive cells and tissues - importance to cell metabolism, function and dysfunction

The beneficial effects of Zn on Akt-mediated insulin and cell survival signaling pathways in diabetes

(2018) Weixia Sun et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Metabolic fate of glucose and candidate signaling and excess-fuel detoxification pathways in pancreatic β-cells

(2017) Yves Mugabo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fish oil supplementation and insulin sensitivity: a systematic review and meta-analysis

(2017) Huanqing Gao et al.   Lipids in Health and Disease

Molecular mechanisms of ROS production and oxidative stress in diabetes

(2016) P. Newsholme et al.   BIOCHEMICAL JOURNAL

Selenium and Metabolic Disorders: An Emphasis on Type 2 Diabetes Risk

(2016) Ashley N. Ogawa-Wong et al.   Nutrients

Control of Insulin Secretion by Production of Reactive Oxygen Species: Study Performed in Pancreatic Islets from Fed and 48-Hour Fasted Wistar Rats

(2016) Ana Cláudia Munhoz et al.   PLoS One

Natural Nrf2 activators in diabetes

(2015) Angélica Saraí Jiménez-Osorio et al.   CLINICA CHIMICA ACTA

Protective effect of chemically modified SOD on lipid peroxidation and antioxidant status in diabetic rats

(2015) Banu Mansuroğlu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increasedAkkermansiaspp. population in the gut microbiota of mice

(2014) Fernando F Anhê et al.   GUT

Lycopene attenuates insulin signaling deficits, oxidative stress, neuroinflammation, and cognitive impairment in fructose-drinking insulin resistant rats

(2014) Qingqing Yin et al.   NEUROPHARMACOLOGY

RNA Sequencing Identifies Dysregulation of the Human Pancreatic Islet Transcriptome by the Saturated Fatty Acid Palmitate

(2013) Miriam Cnop et al.   DIABETES

Nrf2 Protects Pancreatic  -Cells From Oxidative and Nitrosative Stress in Diabetic Model Mice

(2013) Y. Yagishita et al.   DIABETES

NADPH oxidase inhibition prevents beta cell dysfunction induced by prolonged elevation of oleate in rodents

(2013) K. Koulajian et al.   DIABETOLOGIA

Skeletal Muscle MnSOD, Mitochondrial Complex II, and SIRT3 Enzyme Activities Are Decreased in Maternal Obesity During Human Pregnancy and Gestational Diabetes Mellitus

(2013) Kristen E. Boyle et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

NADPH Oxidase Limits Lipopolysaccharide-Induced Lung Inflammation and Injury in Mice through Reduction-Oxidation Regulation of NF- B Activity

(2013) W. Han et al.   JOURNAL OF IMMUNOLOGY

Type 1 Diabetes Mellitus and Components in Drinking Water and Diet: A Population-Based, Case-Control Study in Prince Edward Island, Canada

(2013) Victoria S. Benson et al.   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2

(2012) K. D. Copps et al.   DIABETOLOGIA

Insulin Resistance and Adiposity in Relation to Serum β-Carotene Levels

(2012) Jose A. Canas et al.   JOURNAL OF PEDIATRICS

Selenium and human health

(2012) Margaret P Rayman   LANCET

Is there a role for neuronal nitric oxide synthase (nNOS) in cytokine toxicity to pancreatic beta cells?

(2012) Ewa Gurgul-Convey et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Nrf2 deficiency improves glucose tolerance in mice fed a high-fat diet

(2012) Yu-Kun Jennifer Zhang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Diabetic Downregulation of Nrf2 Activity via ERK Contributes to Oxidative Stress-Induced Insulin Resistance in Cardiac Cells In Vitro and In Vivo

(2011) Y. Tan et al.   DIABETES

Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production

(2011) E. Jing et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted Expression of Catalase to Mitochondria Prevents Age-Associated Reductions in Mitochondrial Function and Insulin Resistance

(2010) Hui-Young Lee et al.   Cell Metabolism

Peroxisome-Generated Hydrogen Peroxide as Important Mediator of Lipotoxicity in Insulin-Producing Cells

(2010) M. Elsner et al.   DIABETES

The Protective Role of Nrf2 in Streptozotocin-Induced Diabetic Nephropathy

(2010) T. Jiang et al.   DIABETES

Role of metabolically generated reactive oxygen species for lipotoxicity in pancreatic β-cells

(2010) W. Gehrmann et al.   DIABETES OBESITY & METABOLISM

Role of Reactive Oxygen Species in the Progression of Type 2 Diabetes and Atherosclerosis

(2010) Hideaki Kaneto et al.   MEDIATORS OF INFLAMMATION

Radical Mechanisms in Nitrosamine- and Nitrosamide-Induced Whole-Genome Gene Expression Modulations in Caco-2 Cells

(2010) Dennie G. A. J. Hebels et al.   TOXICOLOGICAL SCIENCES

Reactive Oxygen Species Enhance Insulin Sensitivity

(2009) Kim Loh et al.   Cell Metabolism

Association of NAD(P)H Oxidase with Glucose-Induced Insulin Secretion by Pancreatic β-Cells

(2009) D. Morgan et al.   ENDOCRINOLOGY

Reduction of mitochondrial H2O2by overexpressing peroxiredoxin 3 improves glucose tolerance in mice

(2008) Liuji Chen et al.   AGING CELL

Mitochondrial Reactive Oxygen Species Are Obligatory Signals for Glucose-Induced Insulin Secretion

(2008) C. Leloup et al.   DIABETES

Too much of a good thing: why it is bad to stimulate the beta cell to secrete insulin

(2008) K. Aston-Mourney et al.   DIABETOLOGIA

Impaired Insulin Secretion by Diphenyleneiodium Associated with Perturbation of Cytosolic Ca2+Dynamics in Pancreatic β-Cells

(2008) Hirofumi Imoto et al.   ENDOCRINOLOGY

Increased oxidative stress precedes the onset of high-fat diet–induced insulin resistance and obesity

(2008) Naoto Matsuzawa-Nagata et al.   METABOLISM-CLINICAL AND EXPERIMENTAL