NADPH oxidase inhibition prevents beta cell dysfunction induced by prolonged elevation of oleate in rodents

Elevated circulating free fatty acids levels causing pancreatic islet cell dysfunction through oxidative stress

(2014) X. Zhang et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Effects of renin-angiotensin system blockade on islet function in diabetic rats

(2014) L. Yuan et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Deletion of p47 phox attenuates the progression of diabetic nephropathy and reduces the severity of diabetes in the Akita mouse

(2012) G. C. Liu et al.   DIABETOLOGIA

Oleic Acid Modulates Metabolic Substrate Channeling during Glucose-Stimulated Insulin Secretion via NAD(P)H Oxidase

(2011) Laila R. B. Santos et al.   ENDOCRINOLOGY

Apocynin Improves Insulin Resistance through Suppressing Inflammation in High-Fat Diet-Induced Obese Mice

(2011) Ran Meng et al.   MEDIATORS OF INFLAMMATION

Alterations of NADPH Oxidase Activity in Rat Pancreatic Islets Induced by a High-Fat Diet

(2011) Maíra Mello Rezende Valle et al.   PANCREAS

Different effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: role of oxidative stress

(2010) Larysa Yuzefovych et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Lipid-induced pancreatic β-cell dysfunction: focus on in vivo studies

(2010) Adria Giacca et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Phagocyte-like NADPH oxidase promotes cytokine-induced mitochondrial dysfunction in pancreatic β-cells: evidence for regulation by Rac1

(2010) Wasanthi Subasinghe et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Tiam1/Rac1 signaling pathway mediates palmitate-induced, ceramide-sensitive generation of superoxides and lipid peroxides and the loss of mitochondrial membrane potential in pancreatic β-cells

(2010) Ismail Syed et al.   BIOCHEMICAL PHARMACOLOGY

Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells

(2010) Lisa S. Pike et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Effects of pharmacological inhibition of NADPH oxidase or iNOS on pro-inflammatory cytokine, palmitic acid or H2O2-induced mouse islet or clonal pancreatic β-cell dysfunction

(2010) Marta Michalska et al.   BIOSCIENCE REPORTS

Beneficial effects of oligopeptides from marine salmon skin in a rat model of type 2 diabetes

(2010) Cui-Feng Zhu et al.   NUTRITION

Insights into the critical role of NADPH oxidase(s) in the normal and dysregulated pancreatic beta cell

(2009) P. Newsholme et al.   DIABETOLOGIA

Association of NAD(P)H Oxidase with Glucose-Induced Insulin Secretion by Pancreatic β-Cells

(2009) D. Morgan et al.   ENDOCRINOLOGY

Fatty acids as modulators of the cellular production of reactive oxygen species

(2008) Peter Schönfeld et al.   FREE RADICAL BIOLOGY AND MEDICINE

UCP2 is highly expressed in pancreatic  -cells and influences secretion and survival

(2008) J. Diao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Apocynin Is Not an Inhibitor of Vascular NADPH Oxidases but an Antioxidant

(2007) Sabine Heumüller et al.   HYPERTENSION