C7‐Functionalization of Indoles via Organocatalytic Enantioselective Friedel‐Crafts Alkylation of 4‐Amino‐ indoles with 2‐Butene‐1,4‐diones and 3‐Aroylacrylates

Enantioselective Synthesis of 2-Amino-1,1-diarylalkanes Bearing a Carbocyclic Ring Substituted Indole through Asymmetric Catalytic Reaction of Hydroxyindoles with Nitroalkenes

(2018) Carlos Vila et al.   JOURNAL OF ORGANIC CHEMISTRY

Organocatalytic, Enantioselective Friedel–Crafts Reaction of Indoles in the Carbocyclic Ring and Electron-Rich Phenols

(2018) Jin-Yu Liu et al.   ORGANIC LETTERS

Regio and Enantioselective Organocatalytic Friedel–Crafts Alkylation of 4-Aminoindoles at the C7-Position

(2018) Wen Xun et al.   ORGANIC LETTERS

α-Functionalization of 2-Vinylpyridines via a Chiral Phosphine Catalyzed Enantioselective Cross Rauhut–Currier Reaction

(2018) Cong Qin et al.   ORGANIC LETTERS

Enantioselective Friedel–Crafts C2-alkylation of 3-substituted indoles with trifluoropyruvates and cyclic N-sulfonyl α-ketiminoesters

(2018) Bing-Bing Huang et al.   Organic Chemistry Frontiers

Organocatalytic Enantioselective aza-Friedel-Crafts Reactions of Pyrazolinone Ketimines with Hydroxyindoles and Electron-Rich Phenols

(2018) Zhong-Tao Yang et al.   ADVANCED SYNTHESIS & CATALYSIS

Alkyne Hydroheteroarylation: Enantioselective Coupling of Indoles and Alkynes via Rh-Hydride Catalysis

(2017) Faben A. Cruz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalyst-controlled oligomerization for the collective synthesis of polypyrroloindoline natural products

(2017) Christopher R. Jamison et al.   Nature Chemistry

Fiaud’s Acid: A Brønsted Acid Catalyst for Enantioselective Friedel–Crafts Alkylation of Indoles with 2-Alkene-1,4-diones

(2017) Sourav Chatterjee et al.   ORGANIC LETTERS

Hydroxy-Directed Enantioselective Hydroxyalkylation in the Carbocyclic Ring of Indoles

(2017) Marc Montesinos-Magraner et al.   ORGANIC LETTERS

Chiral phosphoric acid catalyzed aza-Friedel-Crafts alkylation of indoles with cyclic aryl α-ketimino esters

(2017) Yunlong Zhao et al.   TETRAHEDRON LETTERS

Catalytic asymmetric C2-nucleophilic substitutions of C3-substituted indoles with ortho-hydroxybenzyl alcohols

(2017) Jia-Le Wu et al.   Organic Chemistry Frontiers

Ruthenium-Catalyzed C−H Arylation of Benzoic Acids and Indole Carboxylic Acids with Aryl Halides

(2016) Marco Simonetti et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Friedel–Crafts Alkylation Reactions of 3-Substituted Indoles with Electron-Deficient Alkenes

(2016) Jian-Quan Weng et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed C–H Arylation of Indoles at the C7 Position

(2016) Youqing Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iridium(iii)-catalyzed regioselective C7-sulfonamidation of indoles

(2016) Zengqiang Song et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective 2-Alkylation of 3-Substituted Indoles with Dual Chiral Lewis Acid/Hydrogen-Bond-Mediated Catalyst

(2016) Zijun Zhou et al.   ORGANIC LETTERS

Organocatalytic Enantioselective Friedel–Crafts Aminoalkylation of Indoles in the Carbocyclic Ring

(2016) Marc Montesinos-Magraner et al.   ACS Catalysis

Rhodium-Catalyzed Regioselective C7-Functionalization of N -Pivaloylindoles

(2015) Lanting Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Asymmetric 1,6-Addition/1,4-Addition Sequence to 2,4-Dienals for the Synthesis of Chiral Chromans

(2015) Pernille H. Poulsen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Sulfinamide Bisphosphine Catalysts: Design, Synthesis, and Application in Highly Enantioselective Intermolecular Cross-Rauhut-Currier Reactions

(2015) Wei Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Brønsted acid-catalyzed Friedel–Crafts alkylation of electron-rich arenes with in situ-generated ortho-quinone methides: highly enantioselective synthesis of diarylindolylmethanes and triarylmethanes

(2015) Satyajit Saha et al.   CHEMICAL COMMUNICATIONS

Strategies for the asymmetric functionalization of indoles: an update

(2015) Renato Dalpozzo   CHEMICAL SOCIETY REVIEWS

Structure and biosynthesis of a macrocyclic peptide containing an unprecedented lysine-to-tryptophan crosslink

(2015) Kelsey R. Schramma et al.   Nature Chemistry

Chiral Phosphoric Acid Catalyzed Highly Enantioselective Friedel–Crafts Alkylation Reaction of C3-Substituted Indoles to β,γ-Unsaturated α-Ketimino Esters

(2015) Bo Bi et al.   ORGANIC LETTERS

Highly Enantioselective Intermolecular Cross Rauhut-Currier Reaction Catalyzed by a Multifunctional Lewis Base Catalyst

(2014) Xuelin Dong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

C7-Derivatization of C3-Alkylindoles Including Tryptophans and Tryptamines

(2014) Richard P. Loach et al.   JOURNAL OF ORGANIC CHEMISTRY

Total syntheses of indolactam alkaloids (−)-indolactam V, (−)-pendolmycin, (−)-lyngbyatoxin A, and (−)-teleocidin A-2

(2014) Noah F. Fine Nathel et al.   Chemical Science

Highly Enantioselective Friedel-Crafts Alkylation/N-Hemiacetalization Cascade Reaction with Indoles

(2013) Hong-Gang Cheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Friedel–Crafts alkylation for synthesis of 2-substituted indole derivatives

(2013) Yulong Zhang et al.   CHEMICAL COMMUNICATIONS

Catalytic Asymmetric Synthesis of Pyrroloindolines via a Rhodium(II)-Catalyzed Annulation of Indoles

(2013) Jillian E. Spangler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective inhibition of reverse transcriptase (RT) of HIV-1 by non-racemic indole-based trifluoropropanoates developed by asymmetric catalysis using recyclable organocatalysts

(2013) Xin Han et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective Synthesis of Spiro Cyclopentane-1,3′-indoles and 2,3,4,9-Tetrahydro-1H-carbazoles by Iridium-Catalyzed Allylic Dearomatization and Stereospecific Migration

(2012) Qing-Feng Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Dearomatization Reactions

(2012) Chun-Xiang Zhuo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Alkaloids from the Root of Isatis indigotica

(2012) Minghua Chen et al.   JOURNAL OF NATURAL PRODUCTS

Asymmetric Friedel-Crafts Reaction of Indoles with Ethyl Trifluoropyruvate Using a Copper(I)-Bisoxazolidine Catalyst

(2011) Christian Wolf et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Enantioselective Total Synthesis of Hodgkinsine B

(2011) Robert H. Snell et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Phosphoric Acids as Versatile Catalysts for Enantioselective Carbon–Carbon Bond Forming Reactions

(2010) Masahiro Terada   BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN

Organocatalytic strategies for the asymmetric functionalization of indoles

(2010) Giuseppe Bartoli et al.   CHEMICAL SOCIETY REVIEWS

Iridium-Catalyzed, Silyl-Directed Borylation of Nitrogen-Containing Heterocycles

(2010) Daniel W. Robbins et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Functionalized Indoles with an α-Stereogenic Ketone Moiety Through an Enantioselective Friedel-Crafts Alkylation with (E)-1,4-Diaryl-2-butene-1,4-diones

(2009) Gonzalo Blay et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Functionalization of Indoles in a New Dimension

(2009) Marco Bandini et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Brønsted acid catalyzed Friedel–Crafts alkylation reactions

(2009) Shu-Li You et al.   CHEMICAL SOCIETY REVIEWS

Catalytic Asymmetric Friedel−Crafts Alkylation ReactionsCopper Showed the Way

(2008) Thomas B. Poulsen et al.   CHEMICAL REVIEWS