AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition
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Title
AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition
Authors
Keywords
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Journal
ACTA PHARMACOLOGICA SINICA
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-06-06
DOI
10.1038/s41401-019-0248-2
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Note: Only part of the references are listed.- MicroRNA-34 family: a potential tumor suppressor and therapeutic candidate in cancer
- (2019) Lu Zhang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
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- (2017) Wei Qi et al. Nature Chemical Biology
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- (2017) Yupeng He et al. Nature Chemical Biology
- Identification of targets of tumor suppressor microRNA-34a using a reporter library system
- (2017) Yoshiaki Ito et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MicroRNA-126 increases chemosensitivity in drug-resistant gastric cancer cells by targeting EZH2
- (2016) Ping Wang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The degradation of EZH2 mediated by lncRNA ANCR attenuated the invasion and metastasis of breast cancer
- (2016) Zhongwei Li et al. CELL DEATH AND DIFFERENTIATION
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- (2016) Chi-Han Li et al. INTERNATIONAL JOURNAL OF CANCER
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- (2016) Ziqiang Zhu et al. PLoS One
- NanoBRET—A Novel BRET Platform for the Analysis of Protein–Protein Interactions
- (2015) Thomas Machleidt et al. ACS Chemical Biology
- The tumor-suppressive and potential therapeutic functions of miR-34a in epithelial carcinomas
- (2015) Brian D. Adams et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- SWI/SNF-mutant cancers depend on catalytic and non-catalytic activity of EZH2
- (2015) Kimberly H Kim et al. NATURE MEDICINE
- The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors
- (2015) Daniel Zingg et al. Nature Communications
- Astemizole Arrests the Proliferation of Cancer Cells by Disrupting the EZH2-EED Interaction of Polycomb Repressive Complex 2
- (2014) Xiangqian Kong et al. JOURNAL OF MEDICINAL CHEMISTRY
- PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies
- (2014) Thomas De Raedt et al. NATURE
- The cellular thermal shift assay for evaluating drug target interactions in cells
- (2014) Rozbeh Jafari et al. Nature Protocols
- The microRNA miR-34a Inhibits Non-Small Cell Lung Cancer (NSCLC) Growth and the CD44hi Stem-Like NSCLC Cells
- (2014) Yang Shi et al. PLoS One
- MiR-32 Functions as a Tumor Suppressor and Directly Targets EZH2 in Human Oral Squamous Cell Carcinoma
- (2014) Jin Xiao MEDICAL SCIENCE MONITOR
- Mir-34: A New Weapon Against Cancer?
- (2014) Gabriella Misso et al. Molecular Therapy-Nucleic Acids
- Targeted disruption of the EZH2–EED complex inhibits EZH2-dependent cancer
- (2013) Woojin Kim et al. Nature Chemical Biology
- Transcriptional regulation by Polycomb group proteins
- (2013) Luciano Di Croce et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia
- (2012) Panagiotis Ntziachristos et al. NATURE MEDICINE
- Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)
- (2012) M. T. McCabe et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- EZH2 Oncogenic Activity in Castration-Resistant Prostate Cancer Cells Is Polycomb-Independent
- (2012) K. Xu et al. SCIENCE
- EZH2 Y641 mutations in follicular lymphoma
- (2011) C Bödör et al. LEUKEMIA
- Context-Specific Regulation of NF-κB Target Gene Expression by EZH2 in Breast Cancers
- (2011) Shuet Theng Lee et al. MOLECULAR CELL
- Regulation of mRNA Translation and Stability by microRNAs
- (2010) Marc Robert Fabian et al. Annual Review of Biochemistry
- Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes
- (2010) Gorica Nikoloski et al. NATURE GENETICS
- Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin
- (2010) Ryan D Morin et al. NATURE GENETICS
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