SWI/SNF-mutant cancers depend on catalytic and non-catalytic activity of EZH2
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Title
SWI/SNF-mutant cancers depend on catalytic and non-catalytic activity of EZH2
Authors
Keywords
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Journal
NATURE MEDICINE
Volume 21, Issue 12, Pages 1491-1496
Publisher
Springer Nature
Online
2015-11-10
DOI
10.1038/nm.3968
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- ATARiS: Computational quantification of gene suppression phenotypes from multisample RNAi screens
- (2012) D. D. Shao et al. GENOME RESEARCH
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- (2012) Giles Robinson et al. NATURE
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- Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer
- (2012) A. H. Shain et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation
- (2012) W. Qi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- EZH2 Oncogenic Activity in Castration-Resistant Prostate Cancer Cells Is Polycomb-Independent
- (2012) K. Xu et al. SCIENCE
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- (2011) Ignacio Varela et al. NATURE
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- (2011) Yaoting Gui et al. NATURE GENETICS
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- ARID1AMutations in Endometriosis-Associated Ovarian Carcinomas
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- Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma
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- (2010) D. W. Parsons et al. SCIENCE
- Hijacking the Chromatin Remodeling Machinery: Impact of SWI/SNF Perturbations in Cancer
- (2009) B. Weissman et al. CANCER RESEARCH
- Understanding the Words of Chromatin Regulation
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- Profiling Critical Cancer Gene Mutations in Clinical Tumor Samples
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- (2008) Pedro P. Medina et al. HUMAN MUTATION
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