Trial watch: dietary interventions for cancer therapy

An evolutionary perspective on immunometabolism

(2019) Andrew Wang et al.   SCIENCE

The effects of short-term fasting on quality of life and tolerance to chemotherapy in patients with breast and ovarian cancer: a randomized cross-over pilot study

(2018) Stephan P. Bauersfeld et al.   BMC CANCER

Low-Protein Diet Induces IRE1α-Dependent Anticancer Immunosurveillance

(2018) Camila Rubio-Patiño et al.   Cell Metabolism

The influence of diet on anti-cancer immune responsiveness

(2018) Laura Soldati et al.   Journal of Translational Medicine

The gut microbiota influences anticancer immunosurveillance and general health

(2018) Bertrand Routy et al.   Nature Reviews Clinical Oncology

Starvation, Stress Resistance, and Cancer

(2018) Roberta Buono et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The intestinal microbiota determines the clinical efficacy of immune checkpoint blockers targeting PD-1/PD-L1

(2018) Lisa Derosa et al.   OncoImmunology

Impact of chemotactic factors and receptors on the cancer immune infiltrate: a bioinformatics study revealing homogeneity and heterogeneity among patient cohorts

(2018) Gautier Stoll et al.   OncoImmunology

Metformin blocks myeloid-derived suppressor cell accumulation through AMPK-DACH1-CXCL1 axis

(2018) Guohui Qin et al.   OncoImmunology

Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1

(2018) Jong-Ho Cha et al.   MOLECULAR CELL

Suppression of insulin feedback enhances the efficacy of PI3K inhibitors

(2018) Benjamin D. Hopkins et al.   NATURE

Targeting mitochondria for cardiovascular disorders: therapeutic potential and obstacles

(2018) Massimo Bonora et al.   Nature Reviews Cardiology

The hallmarks of successful anticancer immunotherapy

(2018) Lorenzo Galluzzi et al.   Science Translational Medicine

Favorable Effects of a Ketogenic Diet on Physical Function, Perceived Energy, and Food Cravings in Women with Ovarian or Endometrial Cancer: A Randomized, Controlled Trial

(2018) Caroline Cohen et al.   Nutrients

Nutritional quality of food as represented by the FSAm-NPS nutrient profiling system underlying the Nutri-Score label and cancer risk in Europe: Results from the EPIC prospective cohort study

(2018) Mélanie Deschasaux et al.   PLOS MEDICINE

Serum cytokine levels in breast cancer patients during neoadjuvant treatment with bevacizumab

(2018) Shakila Jabeen et al.   OncoImmunology

Carbotoxicity—Noxious Effects of Carbohydrates

(2018) Guido Kroemer et al.   CELL

Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade

(2018) Ziming Wang et al.   NATURE MEDICINE

Trial watch: The clinical trial landscape for PD1/PDL1 immune checkpoint inhibitors

(2018) Jun Tang et al.   NATURE REVIEWS DRUG DISCOVERY

Neoadjuvant sipuleucel-T induces both Th1 activation and immune regulation in localized prostate cancer

(2018) Katsunobu Hagihara et al.   OncoImmunology

Associations of fats and carbohydrate intake with cardiovascular disease and mortality in 18 countries from five continents (PURE): a prospective cohort study

(2017) Mahshid Dehghan et al.   LANCET

Modulating the therapeutic response of tumours to dietary serine and glycine starvation

(2017) Oliver D. K. Maddocks et al.   NATURE

Metabolic Hallmarks of Tumor and Immune Cells in the Tumor Microenvironment

(2017) Kathrin Renner et al.   Frontiers in Immunology

IL-32α-induced inflammation constitutes a link between obesity and colon cancer

(2017) Victoria Catalán et al.   OncoImmunology

An epigenetic modifier triggers therapeutic immune responses against breast cancer

(2017) Lorenzo Galluzzi et al.   OncoImmunology

Mevalonate metabolism governs cancer immune surveillance

(2017) Georg Gruenbacher et al.   OncoImmunology

Trial watch: Immunogenic cell death induction by anticancer chemotherapeutics

(2017) Abhishek D. Garg et al.   OncoImmunology

Trial watch: Immune checkpoint blockers for cancer therapy

(2017) Claire Vanpouille-Box et al.   OncoImmunology

Exogenous lipid uptake induces metabolic and functional reprogramming of tumor-associated myeloid-derived suppressor cells

(2017) Amir A. Al-Khami et al.   OncoImmunology

Safety and feasibility of fasting in combination with platinum-based chemotherapy

(2016) Tanya B. Dorff et al.   BMC CANCER

Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance

(2016) Federico Pietrocola et al.   CANCER CELL

Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity

(2016) Stefano Di Biase et al.   CANCER CELL

The Emerging Hallmarks of Cancer Metabolism

(2016) Natalya N. Pavlova et al.   Cell Metabolism

Obesity and Cancer: The Oil that Feeds the Flame

(2016) Joan Font-Burgada et al.   Cell Metabolism

Choice of laboratory animal diet influences intestinal health

(2016) Michael Pellizzon   LAB ANIMAL

Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants

(2016)   LANCET

Body Fatness and Cancer — Viewpoint of the IARC Working Group

(2016) Béatrice Lauby-Secretan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Modified Atkins diet in advanced malignancies - final results of a safety and feasibility trial within the Veterans Affairs Pittsburgh Healthcare System

(2016) Jocelyn L. Tan-Shalaby et al.   Nutrition & Metabolism

Lipid metabolic reprogramming in cancer cells

(2016) S Beloribi-Djefaflia et al.   Oncogenesis

Fasting and cancer treatment in humans: A case series report

(2016) Fernando M. Safdie et al.   Aging-US

Anti-Tumor Effects of Ketogenic Diets in Mice: A Meta-Analysis

(2016) Rainer J. Klement et al.   PLoS One

The effects of short-term fasting on tolerance to (neo) adjuvant chemotherapy in HER2-negative breast cancer patients: a randomized pilot study

(2015) Stefanie de Groot et al.   BMC CANCER

Immunological Effects of Conventional Chemotherapy and Targeted Anticancer Agents

(2015) Lorenzo Galluzzi et al.   CANCER CELL

Autophagy in malignant transformation and cancer progression

(2015) L. Galluzzi et al.   EMBO JOURNAL

Calories, carbohydrates, and cancer therapy with radiation: exploiting the five R’s through dietary manipulation

(2014) Rainer J. Klement et al.   CANCER AND METASTASIS REVIEWS

ERGO: A pilot study of ketogenic diet in recurrent glioblastoma

(2014) JOHANNES RIEGER et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Fast food fever: reviewing the impacts of the Western diet on immunity

(2014) Ian A Myles   Nutrition Journal

Trial Watch

(2014) Fernando Aranda et al.   OncoImmunology

Design of Clinical Trials Evaluating Dietary Interventions in Patients With Functional Gastrointestinal Disorders

(2013) Chu K Yao et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Beyond weight loss: a review of the therapeutic uses of very-low-carbohydrate (ketogenic) diets

(2013) A Paoli et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells

(2013) Cosimo Commisso et al.   NATURE

Metabolic targets for cancer therapy

(2013) Lorenzo Galluzzi et al.   NATURE REVIEWS DRUG DISCOVERY

Trial watch

(2013) Erika Vacchelli et al.   OncoImmunology

Fasting Enhances the Response of Glioma to Chemo- and Radiotherapy

(2012) Fernando Safdie et al.   PLoS One

Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy

(2012) C. Lee et al.   Science Translational Medicine

Prognostic Impact of Vitamin B6 Metabolism in Lung Cancer

(2012) Lorenzo Galluzzi et al.   Cell Reports

The socioeconomic determinants of cancer

(2011) Franco Merletti et al.   Environmental Health

Targeting cancer metabolism: a therapeutic window opens

(2011) Matthew G. Vander Heiden   NATURE REVIEWS DRUG DISCOVERY

Changes in Diet and Lifestyle and Long-Term Weight Gain in Women and Men

(2011) Dariush Mozaffarian et al.   NEW ENGLAND JOURNAL OF MEDICINE

Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice

(2011) M. Michaud et al.   SCIENCE

Reduced Levels of IGF-I Mediate Differential Protection of Normal and Cancer Cells in Response to Fasting and Improve Chemotherapeutic Index

(2010) C. Lee et al.   CANCER RESEARCH

Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer

(2010) Philip W. Kantoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tumor Cell Metabolism: Cancer's Achilles' Heel

(2008) Guido Kroemer et al.   CANCER CELL

Cancer Cell Metabolism: Warburg and Beyond

(2008) Peggy P. Hsu et al.   CELL

Comparisons of Diets Used in Animal Models of High-Fat Feeding

(2008) Craig H. Warden et al.   Cell Metabolism

Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy

(2008) L. Raffaghello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA