Grouping of Poorly Soluble Low (Cyto)Toxic Particles: Example with 15 Selected Nanoparticles and A549 Human Lung Cells

In Vitro Cytotoxicity Evaluation of the Magnéli Phase Titanium Suboxides (TixO2x−1) on A549 Human Lung Cells

(2019) Veno Kononenko et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The hazards and risks of inhaled poorly soluble particles – where do we stand after 30 years of research?

(2019) Paul J. A. Borm et al.   Particle and Fibre Toxicology

Criteria for grouping of manufactured nanomaterials to facilitate hazard and risk assessment, a systematic review of expert opinions

(2018) Nina Elisabeth Landvik et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Differential Contribution of Constituent Metal Ions to the Cytotoxic Effects of Fast-Dissolving Metal-Oxide Nanoparticles

(2018) Jiyoung Jeong et al.   Frontiers in Pharmacology

Biologic effects of nanoparticle-allergen conjugates: time-resolved uptake using an in vitro lung epithelial co-culture model of A549 and THP-1 cells

(2018) Bettina Grotz et al.   Environmental Science-Nano

Toxicity testing of poorly soluble particles, lung overload and lung cancer

(2018) Ruth J. Bevan et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

What is the impact of surface modifications and particle size on commercial titanium dioxide particle samples? – A review of in vivo pulmonary and oral toxicity studies – Revised 11-6-2018

(2018) David B. Warheit et al.   TOXICOLOGY LETTERS

The 3Rs as a framework to support a 21st century approach for nanosafety assessment

(2017) Natalie Burden et al.   Nano Today

Overview on biological implications of metal oxide nanoparticle exposure to human alveolar A549 cell line

(2017) Ansie Martin et al.   Nanotoxicology

Harmful at non-cytotoxic concentrations: SiO2-SPIONs affect surfactant metabolism and lamellar body biogenesis in A549 human alveolar epithelial cells

(2017) Veno Kononenko et al.   Nanotoxicology

The application of bismuth film electrode for measuring Zn(II) under less acidic conditions in the presence of cell culture medium and ZnO nanoparticles

(2017) Tea Romih et al.   SENSORS AND ACTUATORS B-CHEMICAL

Comparative in vitro genotoxicity study of ZnO nanoparticles, ZnO macroparticles and ZnCl 2 to MDCK kidney cells: Size matters

(2017) Veno Kononenko et al.   TOXICOLOGY IN VITRO

Emerging Roles for the Lysosome in Lipid Metabolism

(2017) Ashley M. Thelen et al.   TRENDS IN CELL BIOLOGY

Currentin vitroapproaches to assess nanoparticle interactions with lung cells

(2016) Kleanthis Fytianos et al.   Nanomedicine

Physical Principles of Nanoparticle Cellular Endocytosis

(2015) Sulin Zhang et al.   ACS Nano

Particle engineering to enhance or lessen particle uptake by alveolar macrophages and to influence the therapeutic outcome

(2015) Brijeshkumar Patel et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Respiratory epithelial cells orchestrate pulmonary innate immunity

(2015) Jeffrey A Whitsett et al.   NATURE IMMUNOLOGY

Lung particle overload: old school –new insights?

(2015) Paul Borm et al.   Particle and Fibre Toxicology

A decision-making framework for the grouping and testing of nanomaterials (DF4nanoGrouping)

(2015) Josje H.E. Arts et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Toxicity of copper oxide nanoparticles in lung epithelial cells exposed at the air–liquid interface compared with in vivo assessment

(2015) Xuefang Jing et al.   TOXICOLOGY IN VITRO

Grouping and Read-Across Approaches for Risk Assessment of Nanomaterials

(2015) Agnes Oomen et al.   International Journal of Environmental Research and Public Health

PEGylation of ORMOSIL nanoparticles differently modulates the in vitro toxicity toward human lung cells

(2014) Francesca Moret et al.   ARCHIVES OF TOXICOLOGY

Effects of fullerene C60 nanoparticles on A549 cells

(2014) Fude Wang et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Mechanism-based genotoxicity screening of metal oxide nanoparticles using the ToxTracker panel of reporter cell lines

(2014) Hanna L Karlsson et al.   Particle and Fibre Toxicology

A critical appraisal of existing concepts for the grouping of nanomaterials

(2014) Josje H.E. Arts et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Impact of lung surfactant on wettability and cytotoxicity of nanoparticles

(2014) Monica Ratoi et al.   RSC Advances

Lipid-coated gold nanoparticles promote lamellar body formation in A549 cells

(2013) Meijing Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Concern-driven integrated approaches to nanomaterial testing and assessment – report of the NanoSafety Cluster Working Group 10

(2013) Agnes G. Oomen et al.   Nanotoxicology

Surfactant phospholipid metabolism

(2012) Marianna Agassandian et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Association of the physical and chemical properties and the cytotoxicity of metal oxide nanoparticles: metal ion release, adsorption ability and specific surface area

(2012) Masanori Horie et al.   Metallomics

Amorphous silica coatings on magnetic nanoparticles enhance stability and reduce toxicity toin vitroBEAS-2B cells

(2011) Ori Baber et al.   INHALATION TOXICOLOGY

Progressive severe lung injury by zinc oxide nanoparticles; the role of Zn2+ dissolution inside lysosomes

(2011) Wan-Seob Cho et al.   Particle and Fibre Toxicology

Nanotoxicology and in vitro studies: The need of the hour

(2011) Sumit Arora et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Nanotoxicology: a perspective and discussion of whether or not in vitro testing is a valid alternative

(2010) Martin J. D. Clift et al.   ARCHIVES OF TOXICOLOGY

Nanomedicine in pulmonary delivery

(2010) Heidi Mansour et al.   International Journal of Nanomedicine

Time and space resolved uptake study of silicananoparticles by human cells

(2010) Kayle Shapero et al.   Molecular BioSystems

Pulmonary Surfactant Pathophysiology: Current Models and Open Questions

(2010) Jesús Perez-Gil et al.   PHYSIOLOGY

Comparison of the Mechanism of Toxicity of Zinc Oxide and Cerium Oxide Nanoparticles Based on Dissolution and Oxidative Stress Properties

(2008) Tian Xia et al.   ACS Nano

In vitro investigation of oxide nanoparticle and carbon nanotube toxicity and intracellular accumulation in A549 human pneumocytes

(2008) A. Simon-Deckers et al.   TOXICOLOGY