Properties of the HtrA Protease From Bacterium Helicobacter pylori Whose Activity Is Indispensable for Growth Under Stress Conditions

Extracellular HtrA serine proteases: An emerging new strategy in bacterial pathogenesis

(2018) Steffen Backert et al.   CELLULAR MICROBIOLOGY

Biochemical properties of the HtrA homolog from bacterium Stenotrophomonas maltophilia

(2018) Urszula Zarzecka et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Amino-Terminal Processing of Helicobacter pylori Serine Protease HtrA: Role in Oligomerization and Activity Regulation

(2018) Nicole Albrecht et al.   Frontiers in Microbiology

Overexpression of serine protease HtrA enhances disruption of adherens junctions, paracellular transmigration and type IV secretion of CagA by Helicobacter pylori

(2017) Aileen Harrer et al.   Gut Pathogens

Intra- and intersubunit changes accompanying thermal activation of the HtrA2(Omi) protease homotrimer

(2016) Miroslaw Jarzab et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

The LD loop as an important structural element required for transmission of the allosteric signal in the HtrA (DegP) protease fromEscherichia coli

(2016) Donata Figaj et al.   FEBS Journal

Identification of E-cadherin signature motifs functioning as cleavage sites for Helicobacter pylori HtrA

(2016) Thomas P. Schmidt et al.   Scientific Reports

Helicobacter pylori infection: An overview of bacterial virulence factors and pathogenesis

(2016) Cheng-Yen Kao et al.   Biomedical Journal

Characterisation of worldwide Helicobacter pylori strains reveals genetic conservation and essentiality of serine protease HtrA

(2015) Nicole Tegtmeyer et al.   MOLECULAR MICROBIOLOGY

A Conserved Activation Cluster Is Required for Allosteric Communication in HtrA-Family Proteases

(2015) Anna K. de Regt et al.   STRUCTURE

Structural and Functional Analysis of Human HtrA3 Protease and Its Subdomains

(2015) Przemyslaw Glaza et al.   PLoS One

The LA Loop as an Important Regulatory Element of the HtrA (DegP) Protease fromEscherichia coli

(2014) Donata Figaj et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibiting Helicobacter pylori HtrA protease by addressing a computationally predicted allosteric ligand binding site

(2014) Anna Maria Perna et al.   Chemical Science

Temperature-induced changes of HtrA2(Omi) protease activity and structure

(2012) Dorota Zurawa-Janicka et al.   CELL STRESS & CHAPERONES

Architecture and regulation of HtrA-family proteins involved in protein quality control and stress response

(2012) Guido Hansen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

HtrA Protease Family as Therapeutic Targets

(2012) Joanna Skorko-Glonek et al.   CURRENT PHARMACEUTICAL DESIGN

The stability and activity of recombinantHelicobacter pyloriHtrA under stress conditions

(2012) Benjamin Hoy et al.   JOURNAL OF BASIC MICROBIOLOGY

Distinct Roles of Secreted HtrA Proteases from Gram-negative Pathogens in Cleaving the Junctional Protein and Tumor Suppressor E-cadherin

(2012) Benjamin Hoy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How Helicobacter pylori infection controls gastric acid secretion

(2012) Adam J. Smolka et al.   JOURNAL OF GASTROENTEROLOGY

Cage assembly of DegP protease is not required for substrate-dependent regulation of proteolytic activity or high-temperature cell survival

(2012) S. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid paracellular transmigration of Campylobacter jejuni across polarized epithelial cells without affecting TER: role of proteolytic-active HtrA cleaving E-cadherin but not fibronectin

(2012) Manja Boehm et al.   Gut Pathogens

Recombinant Deg/HtrA proteases fromSynechocystissp. PCC 6803 differ in substrate specificity, biochemical characteristics and mechanism

(2011) Pitter F. Huesgen et al.   BIOCHEMICAL JOURNAL

Covalent Linkage of Distinct Substrate Degrons Controls Assembly and Disassembly of DegP Proteolytic Cages

(2011) Seokhee Kim et al.   CELL

Proteomic analysis of upregulated proteins in Helicobacter pylori under oxidative stress induced by hydrogen peroxide

(2011) Chun-Hao Huang et al.   KAOHSIUNG JOURNAL OF MEDICAL SCIENCES

HTRA proteases: regulated proteolysis in protein quality control

(2011) Tim Clausen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Unique Residues Involved in Activation of the Multitasking Protease/Chaperone HtrA from Chlamydia trachomatis

(2011) Wilhelmina M. Huston et al.   PLoS One

Different Contributions of HtrA Protease and Chaperone Activities toCampylobacter jejuniStress Tolerance and Physiology

(2010) Kristoffer T. Bæk et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Helicobacter pylori adhesion to gastric epithelial cells is mediated by glycan receptors

(2010) A. Magalhães et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Helicobacter pylori HtrA is a new secreted virulence factor that cleaves E-cadherin to disrupt intercellular adhesion

(2010) Benjamin Hoy et al.   EMBO REPORTS

Analysis of Edwardsiella tarda DegP, a serine protease and a protective immunogen

(2010) Xu-dong Jiao et al.   FISH & SHELLFISH IMMUNOLOGY

HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues

(2010) Tobias Krojer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Selective Accumulation of Aggregation-Prone Proteasome Substrates in Response to Proteotoxic Stress

(2009) F. A. Salomons et al.   MOLECULAR AND CELLULAR BIOLOGY

Characterization of the Autocleavage Process of the Escherichia coli HtrA Protein: Implications for its Physiological Role

(2008) A. Jomaa et al.   JOURNAL OF BACTERIOLOGY

The proteolytic activity of the HtrA (DegP) protein from Escherichia coli at low temperatures

(2008) J. Skorko-Glonek et al.   MICROBIOLOGY-SGM

Structural basis for the regulated protease and chaperone function of DegP

(2008) Tobias Krojer et al.   NATURE

Prediction of Extracellular Proteases of the Human Pathogen Helicobacter pylori Reveals Proteolytic Activity of the Hp1018/19 Protein HtrA

(2008) Martin Löwer et al.   PLoS One

Activation of DegP chaperone-protease via formation of large cage-like oligomers upon binding to substrate proteins

(2008) J. Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interplay of PDZ and protease domain of DegP ensures efficient elimination of misfolded proteins

(2008) T. Krojer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA