HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses

Human-Specific Adaptations in Vpu Conferring Anti-tetherin Activity Are Critical for Efficient Early HIV-1 Replication In Vivo

(2018) Eri Yamada et al.   Cell Host & Microbe

STING dependent sensing – Does HIV actually care?

(2018) Christian Krapp et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Multilayered and versatile inhibition of cellular antiviral factors by HIV and SIV accessory proteins

(2018) Daniel Sauter et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Species-specific host factors rather than virus-intrinsic virulence determine primate lentiviral pathogenicity

(2018) Simone Joas et al.   Nature Communications

From APOBEC to ZAP: Diverse mechanisms used by cellular restriction factors to inhibit virus infections

(2018) Mahesh Chemudupati et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Resistance to type 1 interferons is a major determinant of HIV-1 transmission fitness

(2017) Shilpa S. Iyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Primate lentiviruses use at least three alternative strategies to suppress NF-κB-mediated immune activation

(2017) Dominik Hotter et al.   PLoS Pathogens

Making Sense of Multifunctional Proteins: Human Immunodeficiency Virus Type 1 Accessory and Regulatory Proteins and Connections to Transcription

(2017) Tyler B. Faust et al.   Annual Review of Virology

HIV-1 Vpu Mediates HLA-C Downregulation

(2016) Richard Apps et al.   Cell Host & Microbe

Cell Surface Downregulation of NK Cell Ligands by Patient-Derived HIV-1 Vpu and Nef Alleles

(2016) Johanna Galaski et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Vaccinia virus K1 ankyrin repeat protein inhibits NF-κB activation by preventing RelA acetylation

(2016) Ariana G. Bravo Cruz et al.   JOURNAL OF GENERAL VIROLOGY

Near-optimal probabilistic RNA-seq quantification

(2016) Nicolas L Bray et al.   NATURE BIOTECHNOLOGY

Vpu-Mediated Counteraction of Tetherin Is a Major Determinant of HIV-1 Interferon Resistance

(2016) Dorota Kmiec et al.   mBio

Cytokine cascade and networks among MSM HIV seroconverters: implications for early immunotherapy

(2016) Xiaojie Huang et al.   Scientific Reports

SnapShot: Antiviral Restriction Factors

(2015) Silvia F. Kluge et al.   CELL

PQBP1 Is a Proximal Sensor of the cGAS-Dependent Innate Response to HIV-1

(2015) Sunnie M. Yoh et al.   CELL

Factors Associated With Plasma IL-6 Levels During HIV Infection

(2015) Álvaro H. Borges et al.   JOURNAL OF INFECTIOUS DISEASES

HIV Vpu Interferes with NF-κB Activity but Not with Interferon Regulatory Factor 3

(2015) Lara Manganaro et al.   JOURNAL OF VIROLOGY

Intrinsic host restrictions to HIV-1 and mechanisms of viral escape

(2015) Viviana Simon et al.   NATURE IMMUNOLOGY

Impacts of Humanized Mouse Models on the Investigation of HIV-1 Infection: Illuminating the Roles of Viral Accessory Proteins in Vivo

(2015) Eri Yamada et al.   Viruses-Basel

Differential Regulation of NF-κB-Mediated Proviral and Antiviral Host Gene Expression by Primate Lentiviral Nef and Vpu Proteins

(2015) Daniel Sauter et al.   Cell Reports

HIV-1 Vpu Accessory Protein Induces Caspase-mediated Cleavage of IRF3 Transcription Factor

(2014) Sang Yoon Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tumor Necrosis Factor α Is Associated With Viral Control and Early Disease Progression in Patients With HIV Type 1 Infection

(2014) Sagar A. Vaidya et al.   JOURNAL OF INFECTIOUS DISEASES

HIV-1 Infection Causes a Down-Regulation of Genes Involved in Ribosome Biogenesis

(2014) Claudia L. Kleinman et al.   PLoS One

Downmodulation of CCR7 by HIV-1 Vpu Results in Impaired Migration and Chemotactic Signaling within CD4+ T Cells

(2014) Peter W. Ramirez et al.   Cell Reports

Preservation of Tetherin and CD4 Counter-Activities in Circulating Vpu Alleles despite Extensive Sequence Variation within HIV-1 Infected Individuals

(2014) Suzanne Pickering et al.   PLoS Pathogens

Elevated IP10 levels are associated with immune activation and low CD4+ T-cell counts in HIV controller patients

(2013) Nicolas Noel et al.   AIDS

Interleukin-6 and D-dimer levels at seroconversion as predictors of HIV-1 disease progression

(2013) Elizabeth Hamlyn et al.   AIDS

HIV-1 Vpu Does Not Degrade Interferon Regulatory Factor 3

(2013) D. Hotter et al.   JOURNAL OF VIROLOGY

Phenotypic properties of transmitted founder HIV-1

(2013) N. F. Parrish et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PNAS Plus: From the Cover: IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication

(2013) M. R. Jakobsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A rare missense variant abrogates the signaling activity of tetherin/BST-2 without affecting its effect on virus release

(2013) Daniel Sauter et al.   Retrovirology

Immune Activation and Collateral Damage in AIDS Pathogenesis

(2013) Frank Miedema et al.   Frontiers in Immunology

Innate Sensing of HIV-1 Assembly by Tetherin Induces NFκB-Dependent Proinflammatory Responses

(2012) Rui Pedro Galão et al.   Cell Host & Microbe

Dynamic roles for NF-κB in HTLV-I and HIV-1 retroviral pathogenesis

(2012) Jonathan K. Chan et al.   IMMUNOLOGICAL REVIEWS

Vpu Mediates Depletion of Interferon Regulatory Factor 3 during HIV Infection by a Lysosome-Dependent Mechanism

(2012) Brian P. Doehle et al.   JOURNAL OF VIROLOGY

Stimulation of NF- B Activity by the HIV Restriction Factor BST2

(2012) A. Tokarev et al.   JOURNAL OF VIROLOGY

INTERFEROME v2.0: an updated database of annotated interferon-regulated genes

(2012) Irina Rusinova et al.   NUCLEIC ACIDS RESEARCH

Acute Plasma Biomarkers of T Cell Activation Set-Point Levels and of Disease Progression in HIV-1 Infection

(2012) Anne-Sophie Liovat et al.   PLoS One

Plasma IP-10 Is Associated with Rapid Disease Progression in Early HIV-1 Infection

(2012) Yanmei Jiao et al.   VIRAL IMMUNOLOGY

Cooperative contributions of Interferon regulatory factor 1 (IRF1) and IRF8 to interferon-γ-mediated cytotoxic effects on oligodendroglial progenitor cells

(2011) Makoto Horiuchi et al.   Journal of Neuroinflammation

Generation of Transmitted/Founder HIV-1 Infectious Molecular Clones and Characterization of Their Replication Capacity in CD4 T Lymphocytes and Monocyte-Derived Macrophages

(2011) C. Ochsenbauer et al.   JOURNAL OF VIROLOGY

Next-Generation Sequencing Reveals HIV-1-Mediated Suppression of T Cell Activation and RNA Processing and Regulation of Noncoding RNA Expression in a CD4+ T Cell Line

(2011) S. T. Chang et al.   mBio

HIV-1 Vpr induces TLR4/MyD88-mediated IL-6 production and reactivates viral production from latency

(2010) Shigeki Hoshino et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Determinants of Tetherin Antagonism in the Transmembrane Domain of the Human Immunodeficiency Virus Type 1 Vpu Protein

(2010) R. Vigan et al.   JOURNAL OF VIROLOGY

GAGE: generally applicable gene set enrichment for pathway analysis

(2009) Weijun Luo et al.   BMC BIOINFORMATICS

Induction of a Striking Systemic Cytokine Cascade prior to Peak Viremia in Acute Human Immunodeficiency Virus Type 1 Infection, in Contrast to More Modest and Delayed Responses in Acute Hepatitis B and C Virus Infections

(2009) A. R. Stacey et al.   JOURNAL OF VIROLOGY

HIV-1 accessory proteins VPR and Vif modulate antiviral response by targeting IRF-3 for degradation

(2007) Atsushi Okumura et al.   VIROLOGY