Vaccinia virus K1 ankyrin repeat protein inhibits NF-κB activation by preventing RelA acetylation

cFLIPLInterrupts IRF3–CBP–DNA Interactions To Inhibit IRF3-Driven Transcription

(2016) Lauren T. Gates et al.   JOURNAL OF IMMUNOLOGY

Poxviral Ankyrin Proteins

(2015) Michael Herbert et al.   Viruses-Basel

The Evolution of Poxvirus Vaccines

(2015) Lucas Sánchez-Sampedro et al.   Viruses-Basel

Identification of Restriction Factors by Human Genome-Wide RNA Interference Screening of Viral Host Range Mutants Exemplified by Discovery of SAMD9 and WDR6 as Inhibitors of the Vaccinia Virus K1L − C7L − Mutant

(2015) Gilad Sivan et al.   mBio

Protein Kinase R and the Inflammasome

(2014) Howard C.H. Yim et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Regulation of NF-κB by TNF family cytokines

(2014) Matthew S. Hayden et al.   SEMINARS IN IMMUNOLOGY

Ectromelia virus encodes a family of Ankyrin/F-box proteins that regulate NFκB

(2014) Kristin Burles et al.   VIROLOGY

Regulation of the NF-κB-Mediated Transcription of Inflammatory Genes

(2014) Dev Bhatt et al.   Frontiers in Immunology

The IκB kinase complex in NF-κB regulation and beyond

(2013) Michael Hinz et al.   EMBO REPORTS

Vaccinia virus immune evasion: mechanisms, virulence and immunogenicity

(2013) G. L. Smith et al.   JOURNAL OF GENERAL VIROLOGY

Vaccinia Virus Inhibits NF- B-Dependent Gene Expression Downstream of p65 Translocation

(2013) R. P. Sumner et al.   JOURNAL OF VIROLOGY

Genetic Screen of a Library of Chimeric Poxviruses Identifies an Ankyrin Repeat Protein Involved in Resistance to the Avian Type I Interferon Response

(2013) K. Buttigieg et al.   JOURNAL OF VIROLOGY

DARPin-targeting of Measles Virus: Unique Bispecificity, Effective Oncolysis, and Enhanced Safety

(2013) Katrin Friedrich et al.   MOLECULAR THERAPY

Inhibition of interferon gene activation by death-effector domain-containing proteins from the molluscum contagiosum virus

(2013) C. M. H. Randall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clinical development of Modified Vaccinia virus Ankara vaccines

(2013) Sarah C. Gilbert   VACCINE

Analysis of the RelA:CBP/p300 Interaction Reveals Its Involvement in NF-κB-Driven Transcription

(2013) Sulakshana P. Mukherjee et al.   PLOS BIOLOGY

Poxvirus Targeting of E3 Ligase β-TrCP by Molecular Mimicry: A Mechanism to Inhibit NF-κB Activation and Promote Immune Evasion and Virulence

(2013) Daniel S. Mansur et al.   PLoS Pathogens

E2A proteins enhance the histone acetyltransferase activity of the transcriptional co-activators CBP and p300

(2012) Brandy D. Hyndman et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

It takes two to tango: IκBs, the multifunctional partners of NF-κB

(2012) Michael Hinz et al.   IMMUNOLOGICAL REVIEWS

Vaccinia virus protein C4 inhibits NF- B activation and promotes virus virulence

(2012) S. W. J. Ember et al.   JOURNAL OF GENERAL VIROLOGY

The MC159 Protein from the Molluscum Contagiosum Poxvirus Inhibits NF- B Activation by Interacting with the I B Kinase Complex

(2012) C. M. H. Randall et al.   JOURNAL OF IMMUNOLOGY

C7L Family of Poxvirus Host Range Genes Inhibits Antiviral Activities Induced by Type I Interferons and Interferon Regulatory Factor 1

(2012) Xiangzhi Meng et al.   JOURNAL OF VIROLOGY

Polydnavirus Ank Proteins Bind NF-κB Homodimers and Inhibit Processing of Relish

(2012) Kavita Bitra et al.   PLoS Pathogens

Analysis of an ankyrin-like region in Epstein Barr Virus encoded (EBV) BZLF-1 (ZEBRA) protein: implications for interactions with NF-κB and p53

(2011) David H Dreyfus et al.   Virology Journal

Posttranslational modifications of NF-κB: Another layer of regulation for NF-κB signaling pathway

(2010) Bo Huang et al.   CELLULAR SIGNALLING

Viral Double-stranded RNAs from Vaccinia Virus Early or Intermediate Gene Transcripts Possess PKR Activating Function, Resulting in NF-κB Activation, When the K1 Protein Is Absent or Mutated

(2010) Kristen L. Willis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Nuclear Inhibitor of NF- B Encoded by a Poxvirus

(2010) D. G. Diel et al.   JOURNAL OF VIROLOGY

Structure Function Studies of Vaccinia Virus Host Range Protein K1 Reveal a Novel Functional Surface for Ankyrin Repeat Proteins

(2010) Y. Li et al.   JOURNAL OF VIROLOGY

The Myxoma Virus M-T5 Ankyrin Repeat Host Range Protein Is a Novel Adaptor That Coordinately Links the Cellular Signaling Pathways Mediated by Akt and Skp1 in Virus-Infected Cells

(2009) S. J. Werden et al.   JOURNAL OF VIROLOGY

Poxvirus Host Range Protein CP77 Contains an F-Box-Like Domain That Is Necessary To Suppress NF- B Activation by Tumor Necrosis Factor Alpha but Is Independent of Its Host Range Function

(2009) S.-J. Chang et al.   JOURNAL OF VIROLOGY

Vaccinia Virus E3 Suppresses Expression of Diverse Cytokines through Inhibition of the PKR, NF- B, and IRF3 Pathways

(2009) C. Myskiw et al.   JOURNAL OF VIROLOGY

Proteomic screening of variola virus reveals a unique NF- B inhibitor that is highly conserved among pathogenic orthopoxviruses

(2009) M. R. Mohamed et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for Targeting of Human RNA Helicase DDX3 by Poxvirus Protein K7

(2009) Shun-ichiro Oda et al.   STRUCTURE

Definition of epitopes and antigens recognized by vaccinia specific immune responses: Their conservation in variola virus sequences, and use as a model system to study complex pathogens

(2009) Alessandro Sette et al.   VACCINE

The effect of the vaccinia K1 protein on the PKR-eIF2α pathway in RK13 and HeLa cells

(2009) Kristen L. Willis et al.   VIROLOGY

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKɛ-mediated IRF activation

(2008) Martina Schröder et al.   EMBO JOURNAL

Ectromelia Virus Encodes a Novel Family of F-Box Proteins That Interact with the SCF Complex

(2008) N. van Buuren et al.   JOURNAL OF VIROLOGY

Inhibition of IκB Kinase by Vaccinia Virus Virulence Factor B14

(2008) Ron A.-J. Chen et al.   PLoS Pathogens

Poxvirus ankyrin repeat proteins are a unique class of F-box proteins that associate with cellular SCF1 ubiquitin ligase complexes

(2008) S. Sonnberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The highly conserved orthopoxvirus 68k ankyrin-like protein is part of a cellular SCF ubiquitin ligase complex

(2008) Karin M. Sperling et al.   VIROLOGY

CD4-Specific Designed Ankyrin Repeat Proteins Are Novel Potent HIV Entry Inhibitors with Unique Characteristics

(2008) Andreas Schweizer et al.   PLoS Pathogens

PKR Regulates TLR2/TLR4-Dependent Signaling in Murine Alveolar Macrophages

(2007) Maciej Cabanski et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY