Primate lentiviruses use at least three alternative strategies to suppress NF-κB-mediated immune activation

Activation of the DNA Damage Response Is a Conserved Function of HIV-1 and HIV-2 Vpr That Is Independent of SLX4 Recruitment

(2016) Oliver I. Fregoso et al.   mBio

HIV-1 Vpr N-terminal tagging affects alternative splicing of the viral genome

(2016) Ann Baeyens et al.   Scientific Reports

Cyclin L2 Is a Critical HIV Dependency Factor in Macrophages that Controls SAMHD1 Abundance

(2015) George Boateng Kyei et al.   Cell Host & Microbe

Vpr Enhances Tumor Necrosis Factor Production by HIV-1-Infected T Cells

(2015) Ferdinand Roesch et al.   JOURNAL OF VIROLOGY

HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation

(2015) Annachiara Rosa et al.   NATURE

Multiple Protein Kinases via Activation of Transcription Factors NF-κB, AP-1 and C/EBP-δ Regulate the IL-6/IL-8 Production by HIV-1 Vpr in Astrocytes

(2015) Mohitkumar R. Gangwani et al.   PLoS One

IFI44 suppresses HIV-1 LTR promoter activity and facilitates its latency

(2015) Derek Power et al.   VIROLOGY

Innate immune sensing of HIV-1 infection

(2015) Martin R. Jakobsen et al.   Current Opinion in HIV and AIDS

Differential Regulation of NF-κB-Mediated Proviral and Antiviral Host Gene Expression by Primate Lentiviral Nef and Vpu Proteins

(2015) Daniel Sauter et al.   Cell Reports

HIV-1 Vpr protein activates the NF-κB pathway to promote G2/M cell cycle arrest

(2015) Zhibin Liang et al.   VIROLOGICA SINICA

Modest Attenuation of HIV-1 Vpu Alleles Derived from Elite Controller Plasma

(2015) Jingyan Chen et al.   PLoS One

Premature Activation of the SLX4 Complex by Vpr Promotes G2/M Arrest and Escape from Innate Immune Sensing

(2014) Nadine Laguette et al.   CELL

G2/M Cell Cycle Arrest Correlates with Primate Lentiviral Vpr Interaction with the SLX4 Complex

(2014) Gregory Berger et al.   JOURNAL OF VIROLOGY

HIV-1 Vpr stimulates NF-κB and AP-1 signaling by activating TAK1

(2014) Ruikang Liu et al.   Retrovirology

Roles of HIV-1 capsid in viral replication and immune evasion

(2014) Valerie Le Sage et al.   VIRUS RESEARCH

HIV-1 Vpu Does Not Degrade Interferon Regulatory Factor 3

(2013) D. Hotter et al.   JOURNAL OF VIROLOGY

Phenotypic properties of transmitted founder HIV-1

(2013) N. F. Parrish et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery and full genome characterization of two highly divergent simian immunodeficiency viruses infecting black-and-white colobus monkeys (Colobus guereza) in Kibale National Park, Uganda

(2013) Michael Lauck et al.   Retrovirology

HIV-1 Vpr activates both canonical and noncanonical NF-κB pathway by enhancing the phosphorylation of IKKα/β

(2013) Ruikang Liu et al.   VIROLOGY

Evolutionary Toggling of Vpx/Vpr Specificity Results in Divergent Recognition of the Restriction Factor SAMHD1

(2013) Oliver I. Fregoso et al.   PLoS Pathogens

Evolution of vertebrate interferon inducible transmembrane proteins

(2012) Danielle Hickford et al.   BMC GENOMICS

Evolutionary and Functional Analyses of the Interaction between the Myeloid Restriction Factor SAMHD1 and the Lentiviral Vpx Protein

(2012) Nadine Laguette et al.   Cell Host & Microbe

The Cytoplasmic Domain of the HIV-1 Glycoprotein gp41 Induces NF-κB Activation through TGF-β-Activated Kinase 1

(2012) Thomas S. Postler et al.   Cell Host & Microbe

Dynamic roles for NF-κB in HTLV-I and HIV-1 retroviral pathogenesis

(2012) Jonathan K. Chan et al.   IMMUNOLOGICAL REVIEWS

Inhibition of NF-κB activity by HIV-1 Vpr is dependent on Vpr binding protein

(2012) Michael Kogan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Regulation of NF-κB induction by TCR/CD28

(2011) Jing Cheng et al.   IMMUNOLOGIC RESEARCH

Extensive characterization of NF-κB binding uncovers non-canonical motifs and advances the interpretation of genetic functional traits

(2011) Daniel Wong et al.   GENOME BIOLOGY

The Presence of a vpu Gene and the Lack of Nef-Mediated Downmodulation of T Cell Receptor-CD3 Are Not Always Linked in Primate Lentiviruses

(2010) J. Schmokel et al.   JOURNAL OF VIROLOGY

Island Biogeography Reveals the Deep History of SIV

(2010) M. Worobey et al.   SCIENCE

Tetherin-Driven Adaptation of Vpu and Nef Function and the Evolution of Pandemic and Nonpandemic HIV-1 Strains

(2009) Daniel Sauter et al.   Cell Host & Microbe

Cross-reactive monoclonal antibodies to multiple HIV-1 subtype and SIVcpz envelope glycoproteins

(2009) Feng Gao et al.   VIROLOGY