Twenty-Five Years of Structural Parvovirology

Examination and reconstruction of three ancient endogenous parvovirus capsid protein gene remnants found in rodent genomes

(2019) Heather M. Callaway et al.   JOURNAL OF VIROLOGY

Novel chimeric gene therapy vectors based on Adeno-associated virus (AAV) and four different mammalian bocaviruses (BoV)

(2019) Julia Fakhiri et al.   Molecular Therapy-Methods & Clinical Development

Adeno-associated virus 2 bound to its cellular receptor AAVR

(2019) Ran Zhang et al.   Nature Microbiology

Protease-Activatable Adeno-Associated Virus Vector for Gene Delivery to Damaged Heart Tissue

(2019) Caitlin M. Guenther et al.   MOLECULAR THERAPY

Structure of parvovirus B19 decorated by Fabs from a human antibody

(2019) Yingyuan Sun et al.   JOURNAL OF VIROLOGY

ICTV Virus Taxonomy Profile: Parvoviridae

(2019) Susan F. Cotmore et al.   JOURNAL OF GENERAL VIROLOGY

Atomic structure of a rationally engineered gene delivery vector, AAV2.5

(2018) Matthew Burg et al.   JOURNAL OF STRUCTURAL BIOLOGY

AAV6 K531 serves a dual function in selective receptor and antibody ADK6 recognition

(2018) Antonette D. Bennett et al.   VIROLOGY

Atomic Resolution Structures of Human Bufaviruses Determined by Cryo-Electron Microscopy

(2018) Maria Ilyas et al.   Viruses-Basel

Intracellular Localization of Blattella germanica Densovirus (BgDV1) Capsid Proteins

(2018) Evgeny Kozlov et al.   Viruses-Basel

An Atypical Parvovirus Drives Chronic Tubulointerstitial Nephropathy and Kidney Fibrosis

(2018) Ben Roediger et al.   CELL

Mapping an Adeno-associated Virus 9-Specific Neutralizing Epitope To Develop Next-Generation Gene Delivery Vectors

(2018) April R. Giles et al.   JOURNAL OF VIROLOGY

Sub-2 Å Ewald curvature corrected structure of an AAV2 capsid variant

(2018) Yong Zi Tan et al.   Nature Communications

High-Resolution Structural Characterization of a New Adeno-associated Virus Serotype 5 Antibody Epitope toward Engineering Antibody-Resistant Recombinant Gene Delivery Vectors

(2018) Ariana Jose et al.   JOURNAL OF VIROLOGY

Understanding capsid assembly and genome packaging for adeno-associated viruses

(2017) Antonette Bennett et al.   Future Virology

Structural Insights into Human Bocaparvoviruses

(2017) Mario Mietzsch et al.   JOURNAL OF VIROLOGY

Structure-guided evolution of antigenically distinct adeno-associated virus variants for immune evasion

(2017) Longping Victor Tse et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atomic Resolution Structure of the Oncolytic Parvovirus LuIII by Electron Microscopy and 3D Image Reconstruction

(2017) Nikéa Pittman et al.   Viruses-Basel

The 2.8 Å Electron Microscopy Structure of Adeno-Associated Virus-DJ Bound by a Heparinoid Pentasaccharide

(2017) Qing Xie et al.   Molecular Therapy-Methods & Clinical Development

Effective Depletion of Pre-existing Anti-AAV Antibodies Requires Broad Immune Targeting

(2017) Victoria M. Velazquez et al.   Molecular Therapy-Methods & Clinical Development

Structural basis for biologically relevant mechanical stiffening of a virus capsid by cavity-creating or spacefilling mutations

(2017) Pablo Guerra et al.   Scientific Reports

Human Parvoviruses

(2016) Jianming Qiu et al.   CLINICAL MICROBIOLOGY REVIEWS

Diversity of small, single-stranded DNA viruses of invertebrates and their chaotic evolutionary past

(2016) Peter Tijssen et al.   JOURNAL OF INVERTEBRATE PATHOLOGY

Mutants at the 2-Fold Interface of Adeno-associated Virus Type 2 (AAV2) Structural Proteins Suggest a Role in Viral Transcription for AAV Capsids

(2016) Fikret Aydemir et al.   JOURNAL OF VIROLOGY

Mapping Antigenic Epitopes on the Human Bocavirus Capsid

(2016) Shweta Kailasan et al.   JOURNAL OF VIROLOGY

Characterization of the Adeno-Associated Virus 1 and 6 Sialic Acid Binding Site

(2016) Lin-Ya Huang et al.   JOURNAL OF VIROLOGY

Cryo-electron Microscopy Reconstruction and Stability Studies of the Wild Type and the R432A Variant of Adeno-associated Virus Type 2 Reveal that Capsid Structural Stability Is a Major Factor in Genome Packaging

(2016) Lauren M. Drouin et al.   JOURNAL OF VIROLOGY

Near-Atomic Resolution Structure of a Highly Neutralizing Fab Bound to Canine Parvovirus

(2016) Lindsey J. Organtini et al.   JOURNAL OF VIROLOGY

An essential receptor for adeno-associated virus infection

(2016) S. Pillay et al.   NATURE

Discovery of a novel Parvovirinae virus, porcine parvovirus 7, by metagenomic sequencing of porcine rectal swabs

(2016) Rachel M. Palinski et al.   VIRUS GENES

Structure of neurotropic adeno-associated virus AAVrh.8

(2015) Sujata Halder et al.   JOURNAL OF STRUCTURAL BIOLOGY

The structure of AAVrh32.33, a novel gene delivery vector

(2014) Kyle Mikals et al.   JOURNAL OF STRUCTURAL BIOLOGY

Defining the Stoichiometry and Cargo Load of Viral and Bacterial Nanoparticles by Orbitrap Mass Spectrometry

(2014) Joost Snijder et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Antibody-Mediated Enhancement of Parvovirus B19 Uptake into Endothelial Cells Mediated by a Receptor for Complement Factor C1q

(2014) Kristina von Kietzell et al.   JOURNAL OF VIROLOGY

Structure of an Enteric Pathogen, Bovine Parvovirus

(2014) Shweta Kailasan et al.   JOURNAL OF VIROLOGY

Gene Expression of Five Different Iteradensoviruses: Bombyx mori Densovirus, Casphalia extranea Densovirus, Papilio polyxenes Densovirus, Sibine fusca Densovirus, and Danaus plexippus Densovirus

(2014) Q. Yu et al.   JOURNAL OF VIROLOGY

Identification and Mutagenesis of the Adeno-Associated Virus 5 Sialic Acid Binding Region

(2014) Sandra Afione et al.   JOURNAL OF VIROLOGY

Global Displacement of Canine Parvovirus by a Host-Adapted Variant: Structural Comparison between Pandemic Viruses with Distinct Host Ranges

(2014) Lindsey J. Organtini et al.   JOURNAL OF VIROLOGY

Adeno-Associated Virus Serotype 1 (AAV1)- and AAV5-Antibody Complex Structures Reveal Evolutionary Commonalities in Parvovirus Antigenic Reactivity

(2014) Yu-Shan Tseng et al.   JOURNAL OF VIROLOGY

Parvovirus glycan interactions

(2014) Lin-Ya Huang et al.   Current Opinion in Virology

Mapping the AAV Capsid Host Antibody Response toward the Development of Second Generation Gene Delivery Vectors

(2014) Yu-Shan Tseng et al.   Frontiers in Immunology

Immune responses to AAV vectors: overcoming barriers to successful gene therapy

(2013) F. Mingozzi et al.   BLOOD

Expression Strategy of Aedes albopictus Densovirus

(2013) H. T. Pham et al.   JOURNAL OF VIROLOGY

The Structure and Host Entry of an Invertebrate Parvovirus

(2013) Geng Meng et al.   JOURNAL OF VIROLOGY

Densovirus Crosses the Insect Midgut by Transcytosis and Disturbs the Epithelial Barrier Function

(2013) Y. Wang et al.   JOURNAL OF VIROLOGY

Structural Characterization of H-1 Parvovirus: Comparison of Infectious Virions to Empty Capsids

(2013) S. Halder et al.   JOURNAL OF VIROLOGY

Structural Insights into Adeno-Associated Virus Serotype 5

(2013) L. Govindasamy et al.   JOURNAL OF VIROLOGY

Structure and Dynamics of Adeno-Associated Virus Serotype 1 VP1-Unique N-Terminal Domain and Its Role in Capsid Trafficking

(2013) B. Venkatakrishnan et al.   JOURNAL OF VIROLOGY

Capsid Antibodies to Different Adeno-Associated Virus Serotypes Bind Common Regions

(2013) B. L. Gurda et al.   JOURNAL OF VIROLOGY

Differential Adeno-Associated Virus Serotype-Specific Interaction Patterns with Synthetic Heparins and Other Glycans

(2013) M. Mietzsch et al.   JOURNAL OF VIROLOGY

Bioinformatical analysis of nuclear localisation sequences in penaeid densoviruses

(2013) Leigh Owens   Marine Genomics

Optimization of the Capsid of Recombinant Adeno-Associated Virus 2 (AAV2) Vectors: The Final Threshold?

(2013) George V. Aslanidi et al.   PLoS One

In Vivo-Directed Evolution of a New Adeno-Associated Virus for Therapeutic Outer Retinal Gene Delivery from the Vitreous

(2013) D. Dalkara et al.   Science Translational Medicine

Overcoming Preexisting Humoral Immunity to AAV Using Capsid Decoys

(2013) F. Mingozzi et al.   Science Translational Medicine

Bioengineering of AAV2 Capsid at Specific Serine, Threonine, or Lysine Residues Improves Its Transduction Efficiency in Vitro and in Vivo

(2013) Nishanth Gabriel et al.   Human Gene Therapy Methods

Nuclear translocation of adeno-associated virus type 2 capsid proteins for virion assembly

(2012) R. Popa-Wagner et al.   JOURNAL OF GENERAL VIROLOGY

Impact of VP1-Specific Protein Sequence Motifs on Adeno-Associated Virus Type 2 Intracellular Trafficking and Nuclear Entry

(2012) R. Popa-Wagner et al.   JOURNAL OF VIROLOGY

Four Amino Acids of an Insect Densovirus Capsid Determine Midgut Tropism and Virulence

(2012) C. Multeau et al.   JOURNAL OF VIROLOGY

Structural Insight into the Unique Properties of Adeno-Associated Virus Serotype 9

(2012) M. A. DiMattia et al.   JOURNAL OF VIROLOGY

Mapping a Neutralizing Epitope onto the Capsid of Adeno-Associated Virus Serotype 8

(2012) B. L. Gurda et al.   JOURNAL OF VIROLOGY

Successful Regional Delivery and Long-term Expression of a Dystrophin Gene in Canine Muscular Dystrophy: A Preclinical Model for Human Therapies

(2012) Zejing Wang et al.   MOLECULAR THERAPY

Differential Seroprevalence of Human Bocavirus Species 1-4 in Beijing, China

(2012) Li Guo et al.   PLoS One

Structure of AAV-DJ, a Retargeted Gene Therapy Vector: Cryo-Electron Microscopy at 4.5 Å Resolution

(2012) Thomas F. Lerch et al.   STRUCTURE

Structure of adeno-associated virus-2 in complex with neutralizing monoclonal antibody A20

(2012) Dustin M. McCraw et al.   VIROLOGY

Random Insertion of mCherry Into VP3 Domain of Adeno-associated Virus Yields Fluorescent Capsids With no Loss of Infectivity

(2012) Justin Judd et al.   Molecular Therapy-Nucleic Acids

Structure of a Packaging-Defective Mutant of Minute Virus of Mice Indicates that the Genome Is Packaged via a Pore at a 5-Fold Axis

(2011) P. Plevka et al.   JOURNAL OF VIROLOGY

Structural Studies of Adeno-Associated Virus Serotype 8 Capsid Transitions Associated with Endosomal Trafficking

(2011) H.-J. Nam et al.   JOURNAL OF VIROLOGY

The Acheta domesticus Densovirus, Isolated from the European House Cricket, Has Evolved an Expression Strategy Unique among Parvoviruses

(2011) K. Liu et al.   JOURNAL OF VIROLOGY

Structure of Bombyx mori Densovirus 1, a Silkworm Pathogen

(2011) B. Kaufmann et al.   JOURNAL OF VIROLOGY

Directed Evolution of Adeno-associated Virus for Enhanced Gene Delivery and Gene Targeting in Human Pluripotent Stem Cells

(2011) Prashanth Asuri et al.   MOLECULAR THERAPY

Phase 1 Gene Therapy for Duchenne Muscular Dystrophy Using a Translational Optimized AAV Vector

(2011) Dawn E Bowles et al.   MOLECULAR THERAPY

Structure–function analysis of receptor-binding in adeno-associated virus serotype 6 (AAV-6)

(2011) Qing Xie et al.   VIROLOGY

Identification of the heparin binding site on adeno-associated virus serotype 3B (AAV-3B)

(2011) Thomas F. Lerch et al.   VIROLOGY

PONDR-FIT: A meta-predictor of intrinsically disordered amino acids

(2010) Bin Xue et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Prevalence of Serum IgG and Neutralizing Factors Against Adeno-Associated Virus (AAV) Types 1, 2, 5, 6, 8, and 9 in the Healthy Population: Implications for Gene Therapy Using AAV Vectors

(2010) Sylvie Boutin et al.   HUMAN GENE THERAPY

Structure of Penaeus stylirostris Densovirus, a Shrimp Pathogen

(2010) B. Kaufmann et al.   JOURNAL OF VIROLOGY

Structural Characterization of the Dual Glycan Binding Adeno-Associated Virus Serotype 6

(2010) R. Ng et al.   JOURNAL OF VIROLOGY

Preexisting Immunity and Low Expression in Primates Highlight Translational Challenges for Liver-directed AAV8-mediated Gene Therapy

(2010) Gregory D Hurlbut et al.   MOLECULAR THERAPY

Epidermal growth factor receptor is a co-receptor for adeno-associated virus serotype 6

(2010) Melodie L Weller et al.   NATURE MEDICINE

Dali server: conservation mapping in 3D

(2010) Liisa Holm et al.   NUCLEIC ACIDS RESEARCH

BAAV Transcytosis Requires an Interaction with β-1-4 Linked- Glucosamine and gp96

(2010) Giovanni Di Pasquale et al.   PLoS One

A viral assembly factor promotes AAV2 capsid formation in the nucleolus

(2010) F. Sonntag et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The structure of adeno-associated virus serotype 3B (AAV-3B): Insights into receptor binding and immune evasion

(2010) Thomas F. Lerch et al.   VIROLOGY

BLAST+: architecture and applications

(2009) Christiam Camacho et al.   BMC BIOINFORMATICS

A muscle-targeting peptide displayed on AAV2 improves muscle tropism on systemic delivery

(2009) C-Y Yu et al.   GENE THERAPY

Structure and Expression Strategy of the Genome of Culex pipiens Densovirus, a Mosquito Densovirus with an Ambisense Organization

(2009) E. Baquerizo-Audiot et al.   JOURNAL OF VIROLOGY

Structural Comparison of Different Antibodies Interacting with Parvovirus Capsids

(2009) S. Hafenstein et al.   JOURNAL OF VIROLOGY

Strategies to Modulate Immune Responses: A New Frontier for Gene Therapy

(2009) Valder R Arruda et al.   MOLECULAR THERAPY

Adeno-associated virus-2 and its primary cellular receptor—Cryo-EM structure of a heparin complex

(2009) Jason O'Donnell et al.   VIROLOGY

Gene Therapy Using Adeno-Associated Virus Vectors

(2008) S. Daya et al.   CLINICAL MICROBIOLOGY REVIEWS

Seroprevalence of parvovirus B19 in the German population

(2008) C. RÖHRER et al.   EPIDEMIOLOGY AND INFECTION

Heparin binding induces conformational changes in Adeno-associated virus serotype 2

(2008) Hazel C. Levy et al.   JOURNAL OF STRUCTURAL BIOLOGY

Visualization of the Externalized VP2 N Termini of Infectious Human Parvovirus B19

(2008) B. Kaufmann et al.   JOURNAL OF VIROLOGY

Next generation of adeno-associated virus 2 vectors: Point mutations in tyrosines lead to high-efficiency transduction at lower doses

(2008) L. Zhong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tyrosine-phosphorylation of AAV2 vectors and its consequences on viral intracellular trafficking and transgene expression

(2008) Li Zhong et al.   VIROLOGY

Characterization of the promoter elements and transcription profile of Periplaneta fuliginosa densovirus nonstructural genes

(2008) Bo Yang et al.   VIRUS RESEARCH

Phospholipase A2-like activity of human bocavirus VP1 unique region

(2007) Xiao-Wang Qu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Processing of adeno-associated virus RNA

(2007) Jianming Qiu   Frontiers in Bioscience-Landmark