Mapping a Neutralizing Epitope onto the Capsid of Adeno-Associated Virus Serotype 8

AAVs Anatomy: Roadmap for Optimizing Vectors for Translational Success

(2012) Angela M. Mitchell et al.   CURRENT GENE THERAPY

Intracellular transport of recombinant adeno-associated virus vectors

(2012) M Nonnenmacher et al.   GENE THERAPY

Evaluation of Adeno-Associated Viral Vectors for Liver-Directed Gene Transfer in Dogs

(2011) Peter Bell et al.   HUMAN GENE THERAPY

Impact of Pre-Existing Immunity on Gene Transfer to Nonhuman Primate Liver with Adeno-Associated Virus 8 Vectors

(2011) Lili Wang et al.   HUMAN GENE THERAPY

Long-term functional adeno-associated virus-microdystrophin expression in the dystrophic CXMDj dog

(2011) Taeyoung Koo et al.   JOURNAL OF GENE MEDICINE

Examining the cross-reactivity and neutralization mechanisms of a panel of mAbs against adeno-associated virus serotypes 1 and 5

(2011) C. E. Harbison et al.   JOURNAL OF GENERAL VIROLOGY

The Assembly-Activating Protein Promotes Capsid Assembly of Different Adeno-Associated Virus Serotypes

(2011) F. Sonntag et al.   JOURNAL OF VIROLOGY

AAV8-mediated Hepatic Gene Transfer in Infant Rhesus Monkeys (Macaca mulatta)

(2011) Lili Wang et al.   MOLECULAR THERAPY

Antibody-based protection against HIV infection by vectored immunoprophylaxis

(2011) Alejandro B. Balazs et al.   NATURE

Therapeutic in vivo gene transfer for genetic disease using AAV: progress and challenges

(2011) Federico Mingozzi et al.   NATURE REVIEWS GENETICS

Adenovirus-Associated Virus Vector–Mediated Gene Transfer in Hemophilia B

(2011) Amit C. Nathwani et al.   NEW ENGLAND JOURNAL OF MEDICINE

Heart-targeted adeno-associated viral vectors selected by in vivo biopanning of a random viral display peptide library

(2010) Y Ying et al.   GENE THERAPY

Prevalence of Serum IgG and Neutralizing Factors Against Adeno-Associated Virus (AAV) Types 1, 2, 5, 6, 8, and 9 in the Healthy Population: Implications for Gene Therapy Using AAV Vectors

(2010) Sylvie Boutin et al.   HUMAN GENE THERAPY

Quantitative analysis of cryo-EM density map segmentation by watershed and scale-space filtering, and fitting of structures by alignment to regions

(2010) Grigore D. Pintilie et al.   JOURNAL OF STRUCTURAL BIOLOGY

Structural Characterization of the Dual Glycan Binding Adeno-Associated Virus Serotype 6

(2010) R. Ng et al.   JOURNAL OF VIROLOGY

Preexisting Immunity and Low Expression in Primates Highlight Translational Challenges for Liver-directed AAV8-mediated Gene Therapy

(2010) Gregory D Hurlbut et al.   MOLECULAR THERAPY

The structure of adeno-associated virus serotype 3B (AAV-3B): Insights into receptor binding and immune evasion

(2010) Thomas F. Lerch et al.   VIROLOGY

Intrinsic phospholipase A2 activity of adeno-associated virus is involved in endosomal escape of incoming particles

(2010) Stefanie Stahnke et al.   VIROLOGY

A muscle-targeting peptide displayed on AAV2 improves muscle tropism on systemic delivery

(2009) C-Y Yu et al.   GENE THERAPY

Naturally occurring singleton residues in AAV capsid impact vector performance and illustrate structural constraints

(2009) L H Vandenberghe et al.   GENE THERAPY

Adeno-Associated Virus Capsid Structure Drives CD4-Dependent CD8 + T Cell Response to Vector Encoded Proteins

(2009) Lauren E. Mays et al.   JOURNAL OF IMMUNOLOGY

Worldwide Epidemiology of Neutralizing Antibodies to Adeno‐Associated Viruses

(2009) Roberto Calcedo et al.   JOURNAL OF INFECTIOUS DISEASES

The Pleiotropic Effects of Natural AAV Infections on Liver-directed Gene Transfer in Macaques

(2009) Lili Wang et al.   MOLECULAR THERAPY

Systematic Evaluation of AAV Vectors for Liver directed Gene Transfer in Murine Models

(2009) Lili Wang et al.   MOLECULAR THERAPY

Reengineering a receptor footprint of adeno-associated virus enables selective and systemic gene transfer to muscle

(2009) Aravind Asokan et al.   NATURE BIOTECHNOLOGY

Molecular Engineering of Viral Gene Delivery Vehicles

(2008) David V. Schaffer et al.   Annual Review of Biomedical Engineering

Successful treatment of canine hemophilia by continuous expression of canine FVIIa

(2008) P. Margaritis et al.   BLOOD

In Vitro and In Vivo Gene Therapy Vector Evolution via Multispecies Interbreeding and Retargeting of Adeno-Associated Viruses

(2008) D. Grimm et al.   JOURNAL OF VIROLOGY

Analysis of AAV Serotypes 1–9 Mediated Gene Expression and Tropism in Mice After Systemic Injection

(2008) Carmela Zincarelli et al.   MOLECULAR THERAPY