Evidence of causal effect of major depression on alcohol dependence: findings from the psychiatric genomics consortium

Evaluating the potential role of pleiotropy in Mendelian randomization studies

(2018) Gibran Hemani et al.   HUMAN MOLECULAR GENETICS

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

(2018) Naomi R. Wray et al.   NATURE GENETICS

Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases

(2018) Marie Verbanck et al.   NATURE GENETICS

The MR-Base platform supports systematic causal inference across the human phenome

(2018) Gibran Hemani et al.   eLife

Phenomic Impact of Genetically-Determined Euthyroid Function and Molecular Differences between Thyroid Disorders

(2018) Silvia Ravera et al.   Journal of Clinical Medicine

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

(2018) Raymond K. Walters et al.   NATURE NEUROSCIENCE

Robust inference in summary data Mendelian randomization via the zero modal pleiotropy assumption

(2017) Fernando Pires Hartwig et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117)

(2017) T-K Clarke et al.   MOLECULAR PSYCHIATRY

A framework for the investigation of pleiotropy in two-sample summary data Mendelian randomization

(2017) Jack Bowden et al.   STATISTICS IN MEDICINE

A putative causal relationship between genetically determined female body shape and posttraumatic stress disorder

(2017) Renato Polimanti et al.   Genome Medicine

Orienting the causal relationship between imprecisely measured traits using GWAS summary data

(2017) Gibran Hemani et al.   PLoS Genetics

Genetically determined schizophrenia is not associated with impaired glucose homeostasis

(2017) Renato Polimanti et al.   SCHIZOPHRENIA RESEARCH

Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator

(2016) Jack Bowden et al.   GENETIC EPIDEMIOLOGY

Two-sample Mendelian randomization: avoiding the downsides of a powerful, widely applicable but potentially fallible technique

(2016) Fernando Pires Hartwig et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

A reference panel of 64,976 haplotypes for genotype imputation

(2016)   NATURE GENETICS

Using published data in Mendelian randomization: a blueprint for efficient identification of causal risk factors

(2015) Stephen Burgess et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

(2015) J. Bowden et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Sparse whole-genome sequencing identifies two loci for major depressive disorder

(2015) Na Cai et al.   NATURE

The UK10K project identifies rare variants in health and disease

(2015)   NATURE

An atlas of genetic correlations across human diseases and traits

(2015) Brendan Bulik-Sullivan et al.   NATURE GENETICS

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

Efficient Bayesian mixed-model analysis increases association power in large cohorts

(2015) Po-Ru Loh et al.   NATURE GENETICS

Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank

(2015) Louise V Wain et al.   Lancet Respiratory Medicine

Mendelian randomization: genetic anchors for causal inference in epidemiological studies

(2014) G. Davey Smith et al.   HUMAN MOLECULAR GENETICS

Increased alcohol consumption as a cause of alcoholism, without similar evidence for depression: a Mendelian randomization study

(2014) M. K. Wium-Andersen et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

The heritability of alcohol use disorders: a meta-analysis of twin and adoption studies

(2014) B. Verhulst et al.   PSYCHOLOGICAL MEDICINE

Three Mutually Informative Ways to Understand the Genetic Relationships Among Behavioral Disinhibition, Alcohol Use, Drug Use, Nicotine Use/Dependence, and Their Co-occurrence: Twin Biometry, GCTA, and Genome-Wide Scoring

(2013) Scott I. Vrieze et al.   BEHAVIOR GENETICS

The triangular association of ADH1B genetic polymorphism, alcohol consumption and the risk of depression in older men

(2013) O P Almeida et al.   MOLECULAR PSYCHIATRY

Burden of Depressive Disorders by Country, Sex, Age, and Year: Findings from the Global Burden of Disease Study 2010

(2013) Alize J. Ferrari et al.   PLOS MEDICINE

Alcohol and depression

(2011) Joseph M. Boden et al.   ADDICTION

Treatment-effect estimates adjusted for small-study effects via a limit meta-analysis

(2010) G. Rucker et al.   BIOSTATISTICS

Prospective Study of Alcohol Consumption in the United States: Quantity, Frequency, and Cause-Specific Mortality

(2008) Rosalind A. Breslow et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH