LncRNA NORAD is repressed by the YAP pathway and suppresses lung and breast cancer metastasis by sequestering S100P

Long noncoding RNA NORAD regulates transforming growth factor-β signaling and epithelial-to-mesenchymal transition-like phenotype

(2018) Natsumi Kawasaki et al.   CANCER SCIENCE

SAM68 is required for regulation of Pumilio by the NORAD long noncoding RNA

(2018) Ailone Tichon et al.   GENES & DEVELOPMENT

The NORAD lncRNA assembles a topoisomerase complex critical for genome stability

(2018) Mathias Munschauer et al.   NATURE

TRPS1 shapes YAP/TEAD-dependent transcription in breast cancer cells

(2018) Dana Elster et al.   Nature Communications

OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ

(2018) Zhengkui Zhang et al.   MOLECULAR CELL

Long non-coding RNA 657 suppresses hepatocellular carcinoma cell growth by acting as a molecular sponge of miR-106a-5p to regulate PTEN expression

(2017) Bingren Hu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Long noncoding RNA NORAD, a novel competing endogenous RNA, enhances the hypoxia-induced epithelial-mesenchymal transition to promote metastasis in pancreatic cancer

(2017) Hongzhe Li et al.   Molecular Cancer

NORAD Expression Is Associated with Adverse Prognosis in Esophageal Squamous Cell Carcinoma

(2017) Xiaoliang Wu et al.   Oncology Research and Treatment

Long noncoding RNAs: Re-writing dogmas of RNA processing and stability

(2016) Jeremy E. Wilusz   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

YAP/TAZ at the Roots of Cancer

(2016) Francesca Zanconato et al.   CANCER CELL

Long Noncoding RNAs in Cancer Pathways

(2016) Adam M. Schmitt et al.   CANCER CELL

The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity

(2016) Toshiro Moroishi et al.   CELL

Noncoding RNA NORAD Regulates Genomic Stability by Sequestering PUMILIO Proteins

(2016) Sungyul Lee et al.   CELL

LncRNAs, lost in translation or licence to regulate?

(2016) Alvaro de Andres-Pablo et al.   CURRENT GENETICS

YAP Nuclear Localization in the Absence of Cell-Cell Contact Is Mediated by a Filamentous Actin-dependent, Myosin II- and Phospho-YAP-independent Pathway during Extracellular Matrix Mechanosensing

(2016) Arupratan Das et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A conserved abundant cytoplasmic long noncoding RNA modulates repression by Pumilio proteins in human cells

(2016) Ailone Tichon et al.   Nature Communications

Cancer-associated S100P protein binds and inactivates p53, permits therapy-induced senescence and supports chemoresistance

(2016) Adriana Gibadulinova et al.   Oncotarget

Comprehensive Genomic Characterization of Long Non-coding RNAs across Human Cancers

(2015) Xiaohui Yan et al.   CANCER CELL

A MYC-Driven Change in Mitochondrial Dynamics Limits YAP/TAZ Function in Mammary Epithelial Cells and Breast Cancer

(2015) Björn von Eyss et al.   CANCER CELL

From Discovery to Function: The Expanding Roles of Long NonCoding RNAs in Physiology and Disease

(2015) Miao Sun et al.   ENDOCRINE REVIEWS

Hippo Component TAZ Functions as a Co-repressor and Negatively Regulates ΔNp63Transcription through TEA Domain (TEAD) Transcription Factor

(2015) Ivette Valencia-Sama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The landscape of long noncoding RNAs in the human transcriptome

(2015) Matthew K Iyer et al.   NATURE GENETICS

A basal-like breast cancer-specific role for SRF–IL6 in YAP-induced cancer stemness

(2015) Tackhoon Kim et al.   Nature Communications

Transcriptional Co-repressor Function of the Hippo Pathway Transducers YAP and TAZ

(2015) Minchul Kim et al.   Cell Reports

A Peptide Mimicking VGLL4 Function Acts as a YAP Antagonist Therapy against Gastric Cancer

(2014) Shi Jiao et al.   CANCER CELL

Chromatin Repressive Complexes in Stem Cells, Development, and Cancer

(2014) Anne Laugesen et al.   Cell Stem Cell

K33-Linked Polyubiquitination of Coronin 7 by Cul3-KLHL20 Ubiquitin E3 Ligase Regulates Protein Trafficking

(2014) Wei-Chien Yuan et al.   MOLECULAR CELL

The Biology of YAP/TAZ: Hippo Signaling and Beyond

(2014) Stefano Piccolo et al.   PHYSIOLOGICAL REVIEWS

USP11 regulates PML stability to control Notch-induced malignancy in brain tumours

(2014) Hsin-Chieh Wu et al.   Nature Communications

RNA in unexpected places: long non-coding RNA functions in diverse cellular contexts

(2013) Sarah Geisler et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structure and function of long noncoding RNAs in epigenetic regulation

(2013) Tim R Mercer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Transcriptional profiling of long non-coding RNAs and novel transcribed regions across a diverse panel of archived human cancers

(2013) Alayne L Brunner et al.   GENOME BIOLOGY

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

(2012) Y. Liu-Chittenden et al.   GENES & DEVELOPMENT

S100P Dissociates Myosin IIA Filaments and Focal Adhesion Sites to Reduce Cell Adhesion and Enhance Cell Migration

(2012) Min Du et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The hallmarks of cancer

(2012) Tony Gutschner et al.   RNA Biology

Epigenetic Regulation by Long Noncoding RNAs

(2012) J. T. Lee   SCIENCE

Non-coding RNAs: key regulators of mammalian transcription

(2012) Jennifer F. Kugel et al.   TRENDS IN BIOCHEMICAL SCIENCES

A Cullin3-KLHL20 Ubiquitin Ligase-Dependent Pathway Targets PML to Potentiate HIF-1 Signaling and Prostate Cancer Progression

(2011) Wei-Chien Yuan et al.   CANCER CELL

S100P: a novel therapeutic target for cancer

(2010) Thiruvengadam Arumugam et al.   AMINO ACIDS

The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version

(2010) B. Zhao et al.   GENES & DEVELOPMENT

S100P Is a Novel Interaction Partner and Regulator of IQGAP1

(2010) Annika Heil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of the Ca2+-regulated Ezrin-S100P Interaction and Its Role in Tumor Cell Migration

(2008) Judith Austermann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY