Hippo Component TAZ Functions as a Co-repressor and Negatively Regulates ΔNp63Transcription through TEA Domain (TEAD) Transcription Factor

VGLL4 functions as a new tumor suppressor in lung cancer by negatively regulating the YAP-TEAD transcriptional complex

(2014) Wenjing Zhang et al.   CELL RESEARCH

The Hippo pathway effectors TAZ and YAP in development, homeostasis and disease

(2014) X. Varelas   DEVELOPMENT

The Hippo signaling pathway in stem cell biology and cancer

(2014) J.-S. Mo et al.   EMBO REPORTS

The Hippo pathway in chemotherapeutic drug resistance

(2014) Yulei Zhao et al.   INTERNATIONAL JOURNAL OF CANCER

Tead2 expression levels control the subcellular distribution of Yap and Taz, zyxin expression and epithelial-mesenchymal transition

(2014) M. Diepenbruck et al.   JOURNAL OF CELL SCIENCE

TAZ is required for metastatic activity and chemoresistance of breast cancer stem cells

(2014) M Bartucci et al.   ONCOGENE

ΔNp63α activates CD82 metastasis suppressor to inhibit cancer cell invasion

(2014) J Wu et al.   Cell Death & Disease

YAP inhibits squamous transdifferentiation of Lkb1-deficient lung adenocarcinoma through ZEB2-dependent DNp63 repression

(2014) Yijun Gao et al.   Nature Communications

The Hippo Transducer TAZ Interacts with the SWI/SNF Complex to Regulate Breast Epithelial Lineage Commitment

(2014) Adam Skibinski et al.   Cell Reports

The Hippo effector Yorkie activates transcription by interacting with a histone methyltransferase complex through Ncoa6

(2014) Yun Qing et al.   eLife

BMP4 is a novel transcriptional target and mediator of mammary cell migration downstream of the Hippo pathway component TAZ

(2013) Dulcie Lai et al.   CELLULAR SIGNALLING

The Hippo Effector Yorkie Controls Normal Tissue Growth by Antagonizing Scalloped-Mediated Default Repression

(2013) Laura M. Koontz et al.   DEVELOPMENTAL CELL

Dual role of C/EBPα as an activator and repressor of Gαi2gene transcription

(2013) Jinxian Xu et al.   GENES TO CELLS

The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment

(2013) Randy Johnson et al.   NATURE REVIEWS DRUG DISCOVERY

TAZ Expression as a Prognostic Indicator in Colorectal Cancer

(2013) Hiu-Fung Yuen et al.   PLoS One

Histone Acetylation-Mediated Regulation of the Hippo Pathway

(2013) Dipanjan Basu et al.   PLoS One

Genome-wide Association of Yorkie with Chromatin and Chromatin-Remodeling Complexes

(2013) Hyangyee Oh et al.   Cell Reports

Tumour suppressor genes in chemotherapeutic drug response

(2012) Dulcie Lai et al.   BIOSCIENCE REPORTS

Prognostic Significance of TAZ Expression in Resected Non-Small Cell Lung Cancer

(2012) Mian Xie et al.   Journal of Thoracic Oncology

TAZ Suppresses NFAT5 Activity through Tyrosine Phosphorylation

(2012) E. J. Jang et al.   MOLECULAR AND CELLULAR BIOLOGY

ΔNp63α regulates Erk signaling via MKP3 to inhibit cancer metastasis

(2012) J Bergholz et al.   ONCOGENE

Protein kinases of the Hippo pathway: Regulation and substrates

(2012) Joseph Avruch et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The YAP and TAZ transcription co-activators: Key downstream effectors of the mammalian Hippo pathway

(2012) Wanjin Hong et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The Hippo pathway regulates stem cell proliferation, self-renewal, and differentiation

(2012) Huan Liu et al.   Protein & Cell

Taxol Resistance in Breast Cancer Cells Is Mediated by the Hippo Pathway Component TAZ and Its Downstream Transcriptional Targets Cyr61 and CTGF

(2011) D. Lai et al.   CANCER RESEARCH

SnapShot: The Hippo Signaling Pathway

(2011) Caroline Badouel et al.   CELL

The Hippo Transducer TAZ Confers Cancer Stem Cell-Related Traits on Breast Cancer Cells

(2011) Michelangelo Cordenonsi et al.   CELL

Molecular mechanism of size control in development and human diseases

(2011) Xiaolong Yang et al.   CELL RESEARCH

Lentiviral vector-mediated siRNA knockdown of the YAP gene inhibits growth and induces apoptosis in the SGC7901 gastric cancer cell line

(2011) Jin-Shui Zhu   Molecular Medicine Reports

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal

(2011) Bin Zhao et al.   NATURE CELL BIOLOGY

TAZ is a novel oncogene in non-small cell lung cancer

(2011) Z Zhou et al.   ONCOGENE

Hippo signaling: growth control and beyond

(2010) G. Halder et al.   DEVELOPMENT

The Hippo Signaling Pathway in Development and Cancer

(2010) Duojia Pan   DEVELOPMENTAL CELL

TAZ/WWTR1 is overexpressed in papillary thyroid carcinoma

(2010) Tiziana de Cristofaro et al.   EUROPEAN JOURNAL OF CANCER

Role of ΔNp63γ in Epithelial to Mesenchymal Transition

(2010) Jaime Lindsay et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Both TEAD-Binding and WW Domains Are Required for the Growth Stimulation and Oncogenic Transformation Activity of Yes-Associated Protein

(2009) B. Zhao et al.   CANCER RESEARCH

Mechanisms of transcriptional repression by histone lysine methylation

(2009) Philip Hublitz et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

TEADs Mediate Nuclear Retention of TAZ to Promote Oncogenic Transformation

(2009) Siew Wee Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TEAD Transcription Factors Mediate the Function of TAZ in Cell Growth and Epithelial-Mesenchymal Transition

(2009) Heng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Role for TAZ in Migration, Invasion, and Tumorigenesis of Breast Cancer Cells

(2008) S. W. Chan et al.   CANCER RESEARCH

TAZ is a coactivator for Pax8 and TTF-1, two transcription factors involved in thyroid differentiation

(2008) Tina Di Palma et al.   EXPERIMENTAL CELL RESEARCH

TEAD mediates YAP-dependent gene induction and growth control

(2008) B. Zhao et al.   GENES & DEVELOPMENT

TAZ Promotes Cell Proliferation and Epithelial-Mesenchymal Transition and Is Inhibited by the Hippo Pathway

(2008) Q.-Y. Lei et al.   MOLECULAR AND CELLULAR BIOLOGY