- Home
- Publications
- Publication Search
- Publication Details
Title
LC8/DYNLL1 is a 53BP1 effector and regulates checkpoint activation
Authors
Keywords
-
Journal
NUCLEIC ACIDS RESEARCH
Volume -, Issue -, Pages -
Publisher
Oxford University Press (OUP)
Online
2019-04-02
DOI
10.1093/nar/gkz263
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity
- (2018) Rajat Gupta et al. CELL
- 53BP1 Mediates ATR-Chk1 Signaling and Protects Replication Forks under Conditions of Replication Stress
- (2018) Joonyoung Her et al. MOLECULAR AND CELLULAR BIOLOGY
- Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells
- (2018) Harveer Dev et al. NATURE CELL BIOLOGY
- High speed of fork progression induces DNA replication stress and genomic instability
- (2018) Apolinar Maya-Mendoza et al. NATURE
- 53BP1 cooperation with the REV7–shieldin complex underpins DNA structure-specific NHEJ
- (2018) Hind Ghezraoui et al. NATURE
- The shieldin complex mediates 53BP1-dependent DNA repair
- (2018) Sylvie M. Noordermeer et al. NATURE
- 53BP1–RIF1–shieldin counteracts DSB resection through CST- and Polα-dependent fill-in
- (2018) Zachary Mirman et al. NATURE
- RNF169 limits 53BP1 deposition at DSBs to stimulate single-strand annealing repair
- (2018) Liwei An et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells
- (2018) Yizhou Joseph He et al. NATURE
- The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity
- (2018) Jordan R. Becker et al. Nature Communications
- ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair
- (2017) Justin W.C. Leung et al. GENES & DEVELOPMENT
- 53BP1 and BRCA1 control pathway choice for stalled replication restart
- (2017) Yixi Xu et al. eLife
- 53BP1 ablation rescues genomic instability in mice expressing ‘RING‐less’ BRCA1
- (2016) Minxing Li et al. EMBO REPORTS
- The structural basis of modified nucleosome recognition by 53BP1
- (2016) Marcus D. Wilson et al. NATURE
- MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5′ end resection
- (2015) Vera Boersma et al. NATURE
- REV7 counteracts DNA double-strand break resection and affects PARP inhibition
- (2015) Guotai Xu et al. NATURE
- SET8 methyltransferase activity during the DNA double-strand break response is required for recruitment of 53BP1
- (2014) S. Dulev et al. EMBO REPORTS
- PTIP associates with Artemis to dictate DNA repair pathway choice
- (2014) Jiadong Wang et al. GENES & DEVELOPMENT
- 53BP1, BRCA1, and the Choice between Recombination and End Joining at DNA Double-Strand Breaks
- (2014) J. M. Daley et al. MOLECULAR AND CELLULAR BIOLOGY
- Concerted Activities of Distinct H4K20 Methyltransferases at DNA Double-Strand Breaks Regulate 53BP1 Nucleation and NHEJ-Directed Repair
- (2014) Creighton T. Tuzon et al. Cell Reports
- RIF1 Counteracts BRCA1-mediated End Resection during DNA Repair
- (2013) Lin Feng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- RIF1 Is Essential for 53BP1-Dependent Nonhomologous End Joining and Suppression of DNA Double-Strand Break Resection
- (2013) J. Ross Chapman et al. MOLECULAR CELL
- A Cell Cycle-Dependent Regulatory Circuit Composed of 53BP1-RIF1 and BRCA1-CtIP Controls DNA Repair Pathway Choice
- (2013) Cristina Escribano-Díaz et al. MOLECULAR CELL
- Double strand break repair functions of histone H2AX
- (2013) Ralph Scully et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- 53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark
- (2013) Amélie Fradet-Turcotte et al. NATURE
- Genome engineering using the CRISPR-Cas9 system
- (2013) F Ann Ran et al. Nature Protocols
- Functions and mechanics of dynein motor proteins
- (2013) Anthony J. Roberts et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Double-strand break repair: 53BP1 comes into focus
- (2013) Stephanie Panier et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Histone H4 Lysine 20 methylation: key player in epigenetic regulation of genomic integrity
- (2013) S. Jorgensen et al. NUCLEIC ACIDS RESEARCH
- RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks
- (2013) M. Bohgaki et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of 53BP1 oligomerization in regulating double-strand break repair
- (2013) F. Lottersberger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- 53BP1 Regulates DSB Repair Using Rif1 to Control 5' End Resection
- (2013) M. Zimmermann et al. SCIENCE
- Rif1 Prevents Resection of DNA Breaks and Promotes Immunoglobulin Class Switching
- (2013) M. Di Virgilio et al. SCIENCE
- 53BP1: pro choice in DNA repair
- (2013) Michal Zimmermann et al. TRENDS IN CELL BIOLOGY
- Two Distinct Modes of ATR Activation Orchestrated by Rad17 and Nbs1
- (2013) Bunsyo Shiotani et al. Cell Reports
- Put a RING on it: regulation and inhibition of RNF8 and RNF168 RING finger E3 ligases at DNA damage sites
- (2013) Cristina Bartocci et al. Frontiers in Genetics
- RNF168 Ubiquitinates K13-15 on H2A/H2AX to Drive DNA Damage Signaling
- (2012) Francesca Mattiroli et al. CELL
- A novel ubiquitin mark at the N-terminal tail of histone H2As targeted by RNF168 ubiquitin ligase
- (2012) Marco Gatti et al. CELL CYCLE
- The DNA damage response and cancer therapy
- (2012) Christopher J. Lord et al. NATURE
- DYNLL/LC8: a light chain subunit of the dynein motor complex and beyond
- (2011) Péter Rapali et al. FEBS Journal
- Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications
- (2011) S. E. Polo et al. GENES & DEVELOPMENT
- Directed Evolution Reveals the Binding Motif Preference of the LC8/DYNLL Hub Protein and Predicts Large Numbers of Novel Binders in the Human Proteome
- (2011) Péter Rapali et al. PLoS One
- 53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks
- (2010) Samuel F. Bunting et al. CELL
- Degrees make all the difference: The multifunctionality of histone H4 lysine 20 methylation
- (2010) Yu Wang et al. Epigenetics
- Regulation of Chromatin Architecture by the PWWP Domain-Containing DNA Damage-Responsive Factor EXPAND1/MUM1
- (2010) Michael S.Y. Huen et al. MOLECULAR CELL
- 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers
- (2010) Peter Bouwman et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins
- (2009) Carsten Doil et al. CELL
- The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage
- (2009) Grant S. Stewart et al. CELL
- Human RPA phosphorylation by ATR stimulates DNA synthesis and prevents ssDNA accumulation during DNA-replication stress
- (2009) V. M. Vassin et al. JOURNAL OF CELL SCIENCE
- Monomethylation of Histone H4-Lysine 20 Is Involved in Chromosome Structure and Stability and Is Essential for Mouse Development
- (2009) H. Oda et al. MOLECULAR AND CELLULAR BIOLOGY
- A Selective Requirement for 53BP1 in the Biological Response to Genomic Instability Induced by Brca1 Deficiency
- (2009) Liu Cao et al. MOLECULAR CELL
- The DNA-damage response in human biology and disease
- (2009) Stephen P. Jackson et al. NATURE
- Catalytic Function of the PR-Set7 Histone H4 Lysine 20 Monomethyltransferase Is Essential for Mitotic Entry and Genomic Stability
- (2008) Sabrina I. Houston et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- An Oligomerized 53BP1 Tudor Domain Suffices for Recognition of DNA Double-Strand Breaks
- (2008) O. Zgheib et al. MOLECULAR AND CELLULAR BIOLOGY
- Dynein Light Chain LC8 Is a Dimerization Hub Essential in Diverse Protein Networks†
- (2007) Elisar Barbar BIOCHEMISTRY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation