53BP1–RIF1–shieldin counteracts DSB resection through CST- and Polα-dependent fill-in

The shieldin complex mediates 53BP1-dependent DNA repair

(2018) Sylvie M. Noordermeer et al.   NATURE

PHF11 promotes DSB resection, ATR signaling, and HR

(2017) Yi Gong et al.   GENES & DEVELOPMENT

CTC1-mediated C-strand fill-in is an essential step in telomere length maintenance

(2017) Xuyang Feng et al.   NUCLEIC ACIDS RESEARCH

A POT1 mutation implicates defective telomere end fill-in and telomere truncations in Coats plus

(2016) Hiroyuki Takai et al.   GENES & DEVELOPMENT

TPP1 Blocks an ATR-Mediated Resection Mechanism at Telomeres

(2016) Tatsuya Kibe et al.   MOLECULAR CELL

Stop pulling my strings — what telomeres taught us about the DNA damage response

(2016) Eros Lazzerini-Denchi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

53BP1 fosters fidelity of homology-directed DNA repair

(2016) Fena Ochs et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

53BP1 fosters fidelity of homology-directed DNA repair

(2016) Fena Ochs et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

53BP1 and the LINC Complex Promote Microtubule-Dependent DSB Mobility and DNA Repair

(2015) Francisca Lottersberger et al.   CELL

MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5′ end resection

(2015) Vera Boersma et al.   NATURE

REV7 counteracts DNA double-strand break resection and affects PARP inhibition

(2015) Guotai Xu et al.   NATURE

Super-Resolution Fluorescence Imaging of Telomeres Reveals TRF2-Dependent T-loop Formation

(2013) Ylli Doksani et al.   CELL

RIF1 Is Essential for 53BP1-Dependent Nonhomologous End Joining and Suppression of DNA Double-Strand Break Resection

(2013) J. Ross Chapman et al.   MOLECULAR CELL

Double-strand break repair: 53BP1 comes into focus

(2013) Stephanie Panier et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination

(2013) Jiangbo Tang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Role of 53BP1 oligomerization in regulating double-strand break repair

(2013) F. Lottersberger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

53BP1 Regulates DSB Repair Using Rif1 to Control 5' End Resection

(2013) M. Zimmermann et al.   SCIENCE

53BP1: pro choice in DNA repair

(2013) Michal Zimmermann et al.   TRENDS IN CELL BIOLOGY

Telomeric 3′ Overhangs Derive from Resection by Exo1 and Apollo and Fill-In by POT1b-Associated CST

(2012) Peng Wu et al.   CELL

CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion

(2012) Peili Gu et al.   EMBO JOURNAL

Removal of Shelterin Reveals the Telomere End-Protection Problem

(2012) A. Sfeir et al.   SCIENCE

53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks

(2010) Samuel F. Bunting et al.   CELL

Evolution of CST function in telomere maintenance

(2010) Carolyn Price et al.   CELL CYCLE

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

(2010) Peter Bouwman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A DNA Polymerase-α·Primase Cofactor with Homology to Replication Protein A-32 Regulates DNA Replication in Mammalian Cells

(2009) Darren E. Casteel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Telomere Protection by TPP1 Is Mediated by POT1a and POT1b

(2009) T. Kibe et al.   MOLECULAR AND CELLULAR BIOLOGY

How Shelterin Protects Mammalian Telomeres

(2008) Wilhelm Palm et al.   Annual Review of Genetics