On the central role of mitochondria dysfunction and oxidative stress in Alzheimer’s disease

Mitochondrial Etiology of Neuropsychiatric Disorders

(2018) Liming Pei et al.   BIOLOGICAL PSYCHIATRY

Hippocampal microvasculature changes in association with oxidative stress in Alzheimer's disease

(2018) Abhik Sen et al.   FREE RADICAL BIOLOGY AND MEDICINE

An energetic view of stress: Focus on mitochondria

(2018) Martin Picard et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Mitochondria and Mitochondrial Cascades in Alzheimer’s Disease

(2018) Russell H. Swerdlow   JOURNAL OF ALZHEIMERS DISEASE

Genes Linking Mitochondrial Function, Cognitive Impairment and Depression are Associated with Endophenotypes Serving Precision Medicine

(2018) Peter Petschner et al.   NEUROSCIENCE

Psychological Stress and Mitochondria

(2018) Martin Picard et al.   PSYCHOSOMATIC MEDICINE

Effect of Chronic Oxidative Stress on Neuroinflammatory Response Mediated by CD4+T Cells in Neurodegenerative Diseases

(2018) Helena Solleiro-Villavicencio et al.   Frontiers in Cellular Neuroscience

A bidirectional relationship between sleep and oxidative stress in Drosophila

(2018) Vanessa M. Hill et al.   PLOS BIOLOGY

Sleep Disorders Associated With Alzheimer's Disease: A Perspective

(2018) Anna Brzecka et al.   Frontiers in Neuroscience

Nitrative Stress and Tau Accumulation in Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex (ALS/PDC) in the Kii Peninsula, Japan

(2018) Yukiko Hata et al.   Frontiers in Neuroscience

The Association of Tau With Mitochondrial Dysfunction in Alzheimer's Disease

(2018) Ying Cheng et al.   Frontiers in Neuroscience

A Novel Perspective for Alzheimer's Disease: Vitamin D Receptor Suppression by Amyloid-β and Preventing the Amyloid-β Induced Alterations by Vitamin D in Cortical Neurons

(2018) Erdinç Dursun et al.   JOURNAL OF ALZHEIMERS DISEASE

Low Serum Vitamin D Concentrations in Alzheimer's Disease: A Systematic Review and Meta-Analysis

(2018) Cedric Annweiler et al.   JOURNAL OF ALZHEIMERS DISEASE

Effects of vitamin D on inflammatory and oxidative stress responses of human bronchial epithelial cells exposed to particulate matter

(2018) Paul E. Pfeffer et al.   PLoS One

Aggressive Behaviors in Alzheimer Disease and Mild Cognitive Impairment: Systematic Review and Meta-Analysis

(2018) Rongqin Yu et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

A shower before bedtime may improve the sleep onset latency of youth soccer players

(2017) Craig Whitworth-Turner et al.   European Journal of Sport Science

Micronutrient Therapy for Violent and Aggressive Male Youth: An Open-Label Trial

(2017) Jessica L. Hambly et al.   JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY

Calcipotriol inhibits α-synuclein aggregation in SH-SY5Y neuroblastoma cells by a Calbindin-D28k-dependent mechanism

(2017) Alexandre N. Rcom-H'cheo-Gauthier et al.   JOURNAL OF NEUROCHEMISTRY

Oxidative stress and pro-inflammatory cytokines may act as one of the signals for regulating microRNAs expression in Alzheimer’s disease

(2017) Kedar N. Prasad   MECHANISMS OF AGEING AND DEVELOPMENT

Mitochondrial genes are altered in blood early in Alzheimer's disease

(2017) Katie Lunnon et al.   NEUROBIOLOGY OF AGING

Melatonin ameliorates amygdala-dependent emotional memory deficits in Tg2576 mice by up-regulating the CREB/c-Fos pathway

(2017) Caixia Peng et al.   NEUROSCIENCE LETTERS

Obesity as a risk factor for Alzheimer's disease: weighing the evidence

(2017) S. Alford et al.   Obesity Reviews

Candidate mechanisms underlying the association between sleep-wake disruptions and Alzheimer's disease

(2017) Jonathan Cedernaes et al.   SLEEP MEDICINE REVIEWS

Genetics of Aggression in Alzheimer’s Disease (AD)

(2017) Walter J. Lukiw et al.   Frontiers in Aging Neuroscience

A Mitochondrial Etiology of Neuropsychiatric Disorders

(2017) Douglas C. Wallace   JAMA Psychiatry

Thyroid Function and Alzheimer's Disease

(2017) Zaldy S. Tan et al.   JOURNAL OF ALZHEIMERS DISEASE

HPA Axis Dysregulation Associated to Apolipoprotein E4 Genotype in Alzheimer's Disease

(2017) Francisco J. Gil-Bea et al.   JOURNAL OF ALZHEIMERS DISEASE

The anti-inflammatory and antioxidant effects of melatonin on LPS-stimulated bovine mammary epithelial cells

(2017) Guang-Min Yu et al.   PLoS One

Vitamin D receptor is present on the neuronal plasma membrane and is co-localized with amyloid precursor protein, ADAM10 or Nicastrin

(2017) Erdinç Dursun et al.   PLoS One

Cholinergic Stimulation Improves Oxidative Stress and Inflammation in Experimental Myocardial Infarction

(2017) Otávio C. Bezerra et al.   Scientific Reports

Elevated Plasma Oxidative Stress Markers in Individuals With Intermittent Explosive Disorder and Correlation With Aggression in Humans

(2016) Emil F. Coccaro et al.   BIOLOGICAL PSYCHIATRY

Leptin Dysfunction and Alzheimer’s Disease: Evidence from Cellular, Animal, and Human Studies

(2016) Matthew J. McGuire et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Association of Oxidative Stress with Psychiatric Disorders

(2016) Waseem Hassan et al.   CURRENT PHARMACEUTICAL DESIGN

Estrogens, Neuroinflammation, and Neurodegeneration

(2016) Alessandro Villa et al.   ENDOCRINE REVIEWS

Vitamin D3 Reduces Tissue Damage and Oxidative Stress Caused by Exhaustive Exercise

(2016) Chun-Yen Ke et al.   International Journal of Medical Sciences

Smoking and Cerebral Oxidative Stress and Air Pollution: A Dreadful Equation with Particulate Matter Involved and One More Powerful Reason Not to Smoke Anything!

(2016) Lilian Calderón-Garcidueñas   JOURNAL OF ALZHEIMERS DISEASE

Androgen Deprivation Therapy and Future Alzheimer’s Disease Risk

(2016) Kevin T. Nead et al.   JOURNAL OF CLINICAL ONCOLOGY

Carbonated soft drinks induce oxidative stress and alter the expression of certain genes in the brains of Wistar rats

(2016) ADEL EL-TERRAS et al.   Molecular Medicine Reports

Effects of the potential lithium-mimetic, ebselen, on impulsivity and emotional processing

(2016) Charles Masaki et al.   PSYCHOPHARMACOLOGY

Increased plasma levels of circulating cell-free mitochondrial DNA in suicide attempters: associations with HPA-axis hyperactivity

(2016) D Lindqvist et al.   Translational Psychiatry

The dual roles of cytokines in Alzheimer’s disease: update on interleukins, TNF-α, TGF-β and IFN-γ

(2016) Cong Zheng et al.   Translational Neurodegeneration

Estrogen receptor-α is localized to neurofibrillary tangles in Alzheimer’s disease

(2016) Chunyu Wang et al.   Scientific Reports

Mitochondrial functional impairment in response to environmental toxins in the cardiorenal metabolic syndrome

(2015) Guanghong Jia et al.   ARCHIVES OF TOXICOLOGY

Oxidative stress, mitochondrial dysfunction and neurodegenerative diseases; a mechanistic insight

(2015) Aashiq Hussain Bhat et al.   BIOMEDICINE & PHARMACOTHERAPY

Sex hormone-related neurosteroids differentially rescue bioenergetic deficits induced by amyloid-β or hyperphosphorylated tau protein

(2015) Amandine Grimm et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The impact of luteinizing hormone and testosterone on beta amyloid (Aβ) accumulation: Animal and human clinical studies

(2015) Giuseppe Verdile et al.   HORMONES AND BEHAVIOR

Clinically Significant Symptom Reduction in Children with Attention-Deficit/Hyperactivity Disorder Treated with Micronutrients: An Open-Label Reversal Design Study

(2015) Heather A Gordon et al.   JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY

Physiological Levels of Melatonin Relate to Cognitive Function and Depressive Symptoms: The HEIJO-KYO Cohort

(2015) Kenji Obayashi et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Melatonin ameliorates amyloid beta-induced memory deficits, tau hyperphosphorylation and neurodegeneration via PI3/Akt/GSk3β pathway in the mouse hippocampus

(2015) Tahir Ali et al.   JOURNAL OF PINEAL RESEARCH

Low Testosterone Level and Risk of Alzheimer’s Disease in the Elderly Men: a Systematic Review and Meta-Analysis

(2015) Wenshan Lv et al.   MOLECULAR NEUROBIOLOGY

Prophylactic melatonin significantly reduces Alzheimer’s neuropathology and associated cognitive deficits independent of antioxidant pathways in AβPPswe/PS1 mice

(2015) G. O’Neal-Moffitt et al.   Molecular Neurodegeneration

Oxidative stress as an etiological factor and a potential treatment target of psychiatric disorders. Part 2. Depression, anxiety, schizophrenia and autism

(2015) Irena Smaga et al.   Pharmacological Reports

Oxidative stress as an etiological factor and a potential treatment target of psychiatric disorders. Part 1. Chemical aspects and biological sources of oxidative stress in the brain

(2015) Andrzej Moniczewski et al.   Pharmacological Reports

Mitochondrial functions modulate neuroendocrine, metabolic, inflammatory, and transcriptional responses to acute psychological stress

(2015) Martin Picard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Smoking and increased Alzheimer's disease risk: A review of potential mechanisms

(2014) Timothy C. Durazzo et al.   Alzheimers & Dementia

Serum coenzyme Q10 levels as a predictor of dementia in a Japanese general population

(2014) Yukihiko Momiyama   ATHEROSCLEROSIS

Alzheimer disease: Epidemiology, diagnostic criteria, risk factors and biomarkers

(2014) Christiane Reitz et al.   BIOCHEMICAL PHARMACOLOGY

Melatonin facilitates extinction, but not acquisition or expression, of conditional cued fear in rats

(2014) Fulian Huang et al.   BMC NEUROSCIENCE

Oxidative Stress and Psychological Disorders

(2014) Samina Salim   Current Neuropharmacology

MFN2 Couples Glutamate Excitotoxicity and Mitochondrial Dysfunction in Motor Neurons

(2014) Wenzhang Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A genetic reduction in antioxidant function causes elevated aggression in mice

(2014) M. Garratt et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Alpha-synuclein and tau: teammates in neurodegeneration?

(2014) Simon Moussaud et al.   Molecular Neurodegeneration

Vitamin D and the risk of dementia and Alzheimer disease

(2014) T. J. Littlejohns et al.   NEUROLOGY

Chronic stress as a risk factor for Alzheimer’s disease

(2014) Alberto Machado et al.   REVIEWS IN THE NEUROSCIENCES

Oxidative stress in Alzheimer’s disease

(2014) Zhichun Chen et al.   Neuroscience Bulletin

Mitochondrial DNA (mtDNA) in brain samples from patients with major psychiatric disorders: Gene expression profiles, MtDNA content and presence of the MtDNA common deletion

(2013) Helena Torrell et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

A cross-sectional study on thyroid status in North Indian elderly outpatients with dementia

(2013) Rachna Agarwal et al.   Annals of Indian Academy of Neurology

Oxidative stress and mitochondrial dysfunction in Alzheimer's disease

(2013) Xinglong Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Endogenous progesterone levels and frontotemporal dementia: modulation of TDP-43 and Tau levels in vitro and treatment of the A315T TARDBP mouse model

(2013) T. N. T. Dang et al.   Disease Models & Mechanisms

Mitochondrial dynamics modulate the expression of pro-inflammatory mediators in microglial cells

(2013) Junghyung Park et al.   JOURNAL OF NEUROCHEMISTRY

The Psychiatric Presentation of Mitochondrial Disorders in Adults

(2013) Rebecca E. Anglin et al.   JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES

A two-decade comparison of prevalence of dementia in individuals aged 65 years and older from three geographical areas of England: results of the Cognitive Function and Ageing Study I and II

(2013) Fiona E Matthews et al.   LANCET

Aggressive and impulsive behavior in Alzheimer’s disease and progression of dementia

(2013) Leszek Bidzan et al.   MEDICAL SCIENCE MONITOR

Diphenyl Diselenide Prevents Cortico-cerebral Mitochondrial Dysfunction and Oxidative Stress Induced by Hypercholesterolemia in LDL Receptor Knockout Mice

(2013) Jade de Oliveira et al.   NEUROCHEMICAL RESEARCH

Increased oxidative stress in obesity: Implications for metabolic syndrome, diabetes, hypertension, dyslipidemia, atherosclerosis, and cancer

(2013) Morihiro Matsuda et al.   Obesity Research & Clinical Practice

Mitochondria as a Target of Environmental Toxicants

(2013) Joel N. Meyer et al.   TOXICOLOGICAL SCIENCES

Cognitive dysfunction in mitochondrial disorders

(2012) J. Finsterer   ACTA NEUROLOGICA SCANDINAVICA

Evaluation of the effects of testosterone and luteinizing hormone on regulation of β-amyloid in male 3xTg-AD mice

(2012) Emily R. Rosario et al.   BRAIN RESEARCH

The Mediterranean diet improves the systemic lipid and DNA oxidative damage in metabolic syndrome individuals. A randomized, controlled, trial

(2012) Maria Teresa Mitjavila et al.   CLINICAL NUTRITION

17β-Estradiol and Progesterone Regulate Expression of β-Amyloid Clearance Factors in Primary Neuron Cultures and Female Rat Brain

(2012) Anusha Jayaraman et al.   ENDOCRINOLOGY

Novel S-acyl glutathione derivatives prevent amyloid oxidative stress and cholinergic dysfunction in Alzheimer disease models

(2012) Mariagioia Zampagni et al.   FREE RADICAL BIOLOGY AND MEDICINE

Links between metabolism and cancer

(2012) C. V. Dang   GENES & DEVELOPMENT

The Mechanisms of Positive Effects of Melatonin in Dyslipidemia: A Systematic Review of Animal and Human Studies

(2012) Mohammad Abdollahi et al.   International Journal of Pharmacology

The Psychiatric Manifestations of Mitochondrial Disorders

(2012) Rebecca E. Anglin et al.   JOURNAL OF CLINICAL PSYCHIATRY

A review of the molecular aspects of melatonin’s anti-inflammatory actions: recent insights and new perspectives

(2012) José L. Mauriz et al.   JOURNAL OF PINEAL RESEARCH

Impaired mitochondrial function in psychiatric disorders

(2012) Husseini Manji et al.   NATURE REVIEWS NEUROSCIENCE

Thyroid hormone regulation of APP (β-amyloid precursor protein) gene expression in brain and brain cultured cells

(2012) Constanza Contreras-Jurado et al.   NEUROCHEMISTRY INTERNATIONAL

Raised calcium and oxidative stress cooperatively promote alpha-synuclein aggregate formation

(2012) J. Goodwin et al.   NEUROCHEMISTRY INTERNATIONAL

Ascorbic acid, alpha-tocopherol, and beta-carotene reduce oxidative stress and proinflammatory cytokines in mononuclear cells of Alzheimer's disease patients

(2012) Barbara Fonseca de Oliveira et al.   NUTRITIONAL NEUROSCIENCE

Evidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain

(2012) S Rose et al.   Translational Psychiatry

Neuropsychiatric symptoms in Alzheimer’s disease

(2011) Constantine G. Lyketsos et al.   Alzheimers & Dementia

Melatonin attenuates kainic acid-induced neurotoxicity in mouse hippocampus via inhibition of autophagy and α-synuclein aggregation

(2011) Chia-Fu Chang et al.   JOURNAL OF PINEAL RESEARCH

Thyroid hormone suppression of β-amyloid precursor protein gene expression in the brain involves multiple epigenetic regulatory events

(2011) Madesh Belakavadi et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Effect of melatonin on α-synuclein self-assembly and cytotoxicity

(2011) Kenjiro Ono et al.   NEUROBIOLOGY OF AGING

Mechanism of neuroprotection of melatonin against beta-amyloid neurotoxicity

(2011) M. Ionov et al.   NEUROSCIENCE

Positive correlation between elevated plasma cholesterol levels and cognitive impairments in LDL receptor knockout mice: relevance of cortico-cerebral mitochondrial dysfunction and oxidative stress

(2011) J. de Oliveira et al.   NEUROSCIENCE

Mitochondrial dysfunction in obesity

(2011) Juan C Bournat et al.   Current Opinion in Endocrinology Diabetes and Obesity

A Meta-Analysis of Cytokines in Alzheimer's Disease

(2010) Walter Swardfager et al.   BIOLOGICAL PSYCHIATRY

Testosterone suppresses oxidative stress in human neutrophils

(2010) Douglas Popp Marin et al.   CELL BIOCHEMISTRY AND FUNCTION

Clinical Aspects of Melatonin Intervention in Alzheimers Disease Progression

(2010) Daniel P. Cardinali et al.   Current Neuropharmacology

Mitochondrial Dynamics in Alzheimerʼs Disease

(2010) David J. Bonda et al.   DRUGS & AGING

Production of Proinflammatory Cytokines and Chemokines During Neuroinflammation: Novel Roles for Estrogen Receptors α and β

(2010) Candice M. Brown et al.   ENDOCRINOLOGY

Effects of mitochondrial dysfunction on the immunological properties of microglia

(2010) Annette I Ferger et al.   Journal of Neuroinflammation

Oxidative Stress in the Progression of Alzheimer Disease in the Frontal Cortex

(2010) Mubeen A. Ansari et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Oxidative stress in Alzheimer's disease hippocampus: A topographical study

(2010) F.F. Cruz-Sánchez et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Direct antioxidant and protective effect of estradiol on isolated mitochondria

(2009) Consuelo Borrás et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology

(2009) Paula I. Moreira et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Anti-aggregation and fibril-destabilizing effects of sex hormones on α-synuclein fibrils in vitro

(2009) Mie Hirohata et al.   EXPERIMENTAL NEUROLOGY

Elevation by Oxidative Stress and Aging of Hypothalamic-Pituitary-Adrenal Activity in Rats and Its Prevention by Vitamin E

(2009) Naoko Kobayashi et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Brain levels of sex steroid hormones in men and women during normal aging and in Alzheimer's disease

(2009) Emily R. Rosario et al.   NEUROBIOLOGY OF AGING

Melatonin Modulates Cell Survival of New Neurons in the Hippocampus of Adult Mice

(2009) Gerardo Ramírez-Rodríguez et al.   NEUROPSYCHOPHARMACOLOGY

Role of Synucleins in Alzheimer’s Disease

(2009) Leslie Crews et al.   NEUROTOXICITY RESEARCH

Monoamine oxidase A gene (MAOA) predicts behavioral aggression following provocation

(2009) R. McDermott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coupling diverse routes of calcium entry to mitochondrial dysfunction and glutamate excitotoxicity

(2009) R. I. Stanika et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Melatonin maintains adult hippocampal neurogenesis and cognitive functions after irradiation

(2009) Kailash Manda et al.   PROGRESS IN NEUROBIOLOGY

Reading and solving arithmetic problems improves cognitive functions of normal aged people: a randomized controlled study

(2008) Shinya Uchida et al.   AGE

Effect of thyroid hormone on mitochondrial properties and oxidative stress in cells from patients with mtDNA defects

(2008) Keir J. Menzies et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Mitochondrial involvement in psychiatric disorders

(2008) Ling Shao et al.   ANNALS OF MEDICINE

Oxidative Stress Involvement in α-Synuclein Oligomerization in Parkinson's Disease Cybrids

(2008) A. Raquel Esteves et al.   ANTIOXIDANTS & REDOX SIGNALING

Perceptual metrics of individuals with autism provide evidence for disinhibition

(2008) Vinay Tannan et al.   Autism Research

Fatty acids and oxidative stress in psychiatric disorders

(2008) Sofia Tsaluchidu et al.   BMC Psychiatry

Oxidative stress in psychiatric disorders: evidence base and therapeutic implications

(2008) Felicity Ng et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Cognitive decline as a manifestation of mitochondrial disorders (mitochondrial dementia)

(2008) Josef Finsterer   JOURNAL OF THE NEUROLOGICAL SCIENCES

Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

(2008) P. Hemachandra Reddy et al.   TRENDS IN MOLECULAR MEDICINE