A synthetic genetic polymer with an uncharged backbone chemistry based on alkyl phosphonate nucleic acids

Oligonucleotide analogues with cationic backbone linkages

(2018) Melissa Meng et al.   Beilstein Journal of Organic Chemistry

Phosphonomethyl Oligonucleotides as Backbone-Modified Artificial Genetic Polymers

(2018) Chao Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Strategically Located Arg/Lys Residue Promotes Correct Base Paring During Nucleic Acid Biosynthesis in Polymerases

(2018) Vito Genna et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

OUP accepted manuscript

(2018)   NUCLEIC ACIDS RESEARCH

Second-Shell Basic Residues Expand the Two-Metal-Ion Architecture of DNA and RNA Processing Enzymes

(2018) Vito Genna et al.   STRUCTURE

The Catalytic Mechanism of DNA and RNA Polymerases

(2018) Vito Genna et al.   ACS Catalysis

Reverse Transcription of Threose Nucleic Acid by a Naturally Occurring DNA Polymerase

(2016) Matthew R. Dunn et al.   CHEMBIOCHEM

A Self-Activated Mechanism for Nucleic Acid Polymerization Catalyzed by DNA/RNA Polymerases

(2016) Vito Genna et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cooperative motion of a key positively charged residue and metal ions for DNA replication catalyzed by human DNA Polymerase-η

(2016) Vito Genna et al.   NUCLEIC ACIDS RESEARCH

The Expanded Genetic Alphabet

(2015) Denis A. Malyshev et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A semi-synthetic organism with an expanded genetic alphabet

(2014) Denis A. Malyshev et al.   NATURE

Catalysts from synthetic genetic polymers

(2014) Alexander I. Taylor et al.   NATURE

Mispairs with Watson-Crick base-pair geometry observed in ternary complexes of an RB69 DNA polymerase variant

(2014) Shuangluo Xia et al.   PROTEIN SCIENCE

Structures of KOD and 9°N DNA Polymerases Complexed with Primer Template Duplex

(2013) Konrad Bergen et al.   CHEMBIOCHEM

Structures of an Apo and a Binary Complex of an Evolved Archeal B Family DNA Polymerase Capable of Synthesising Highly Cy-Dye Labelled DNA

(2013) Samantha A. Wynne et al.   PLoS One

Fast and accurate nonenzymatic copying of an RNA-like synthetic genetic polymer

(2013) S. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peptide nucleic acids are an additional class of aptamers

(2013) Eun Jeong Lee et al.   RSC Advances

Synthetic polymers and their potential as genetic materials

(2012) Vitor B. Pinheiro et al.   BIOESSAYS

The XNA world: progress towards replication and evolution of synthetic genetic polymers

(2012) Vitor B Pinheiro et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Alkynyl Phosphonate DNA: A Versatile “Click”able Backbone for DNA-Based Biological Applications

(2012) Heera Krishna et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Watching DNA polymerase η make a phosphodiester bond

(2012) Teruya Nakamura et al.   NATURE

Darwinian evolution of an alternative genetic system provides support for TNA as an RNA progenitor

(2012) Hanyang Yu et al.   Nature Chemistry

A short adaptive path from DNA to RNA polymerases

(2012) C. Cozens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthetic Genetic Polymers Capable of Heredity and Evolution

(2012) V. B. Pinheiro et al.   SCIENCE

Conservative secondary structure motif of streptavidin-binding aptamers generated by different laboratories

(2010) Tao Bing et al.   BIOORGANIC & MEDICINAL CHEMISTRY

An in vitro translation, selection and amplification system for peptide nucleic acids

(2010) Yevgeny Brudno et al.   Nature Chemical Biology