Synthetic polymers and their potential as genetic materials

Different superstructures formed by Janus-type nucleosides

(2012) Hang Zhao et al.   CHEMICAL COMMUNICATIONS

Designing Chemically Modified Oligonucleotides for Targeted Gene Silencing

(2012) Glen F. Deleavey et al.   CHEMISTRY & BIOLOGY

The XNA world: progress towards replication and evolution of synthetic genetic polymers

(2012) Vitor B Pinheiro et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Going beyond five bases in DNA sequencing

(2012) Jonas Korlach et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Ligand-Dependent Exponential Amplification of a Self-Replicating l-RNA Enzyme

(2012) Charles Olea et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multicomponent Assembly of Proposed DNA Precursors in Water

(2012) Matthew W. Powner et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Site-Specific Incorporation of Functional Components into RNA by an Unnatural Base Pair Transcription System

(2012) Nobuyuki Morohashi et al.   MOLECULES

KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry

(2012) Karin Betz et al.   Nature Chemical Biology

Darwinian evolution of an alternative genetic system provides support for TNA as an RNA progenitor

(2012) Hanyang Yu et al.   Nature Chemistry

Y-family DNA polymerases and their role in tolerance of cellular DNA damage

(2012) Julian E. Sale et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Prebiotically plausible mechanisms increase compositional diversity of nucleic acid sequences

(2012) Julien Derr et al.   NUCLEIC ACIDS RESEARCH

The solution structure of double helical arabino nucleic acids (ANA and 2′F-ANA): effect of arabinoses in duplex-hairpin interconversion

(2012) Nerea Martín-Pintado et al.   NUCLEIC ACIDS RESEARCH

A short adaptive path from DNA to RNA polymerases

(2012) C. Cozens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Next-Generation Digital Information Storage in DNA

(2012) G. M. Church et al.   SCIENCE

Synthetic Genetic Polymers Capable of Heredity and Evolution

(2012) V. B. Pinheiro et al.   SCIENCE

Bit by Bit: The Darwinian Basis of Life

(2012) Gerald F. Joyce   PLOS BIOLOGY

Recognition of Double-Stranded RNA by Guanidine-Modified Peptide Nucleic Acids

(2011) Pankaj Gupta et al.   BIOCHEMISTRY

New imidazopyridopyrimidine:naphthyridine base-pairing motif, ImNN:NaOO, consisting of a DAAD:ADDA hydrogen bonding pattern, markedly stabilize DNA duplexes

(2011) Kazuyuki Kuramoto et al.   CHEMICAL COMMUNICATIONS

Triple helical recognition of pyrimidine inversions in polypurine tracts of RNA by nucleobase-modified PNA

(2011) Pankaj Gupta et al.   CHEMICAL COMMUNICATIONS

Solution Structure and Conformational Dynamics of Deoxyxylonucleic Acids (dXNA): An Orthogonal Nucleic Acid Candidate

(2011) Mohitosh Maiti et al.   CHEMISTRY-A EUROPEAN JOURNAL

Amplification, Mutation, and Sequencing of a Six-Letter Synthetic Genetic System

(2011) Zunyi Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Site-Specific Labeling of DNA and RNA Using an Efficiently Replicated and Transcribed Class of Unnatural Base Pairs

(2011) Young Jun Seo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Reversible bond formation enables the replication and amplification of a crosslinking salen complex as an orthogonal base pair

(2011) Corinna Kaul et al.   Nature Chemistry

Recognition of an expanded genetic alphabet by type-II restriction endonucleases and their application to analyze polymerase fidelity

(2011) Fei Chen et al.   NUCLEIC ACIDS RESEARCH

The prebiotic evolutionary advantage of transferring genetic information from RNA to DNA

(2011) Kevin Leu et al.   NUCLEIC ACIDS RESEARCH

Nucleotide Discrimination with DNA Immobilized in the MspA Nanopore

(2011) Elizabeth A. Manrao et al.   PLoS One

Carbonaceous meteorites contain a wide range of extraterrestrial nucleobases

(2011) M. P. Callahan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Incorporation of Thymine Nucleotides by DNA Polymerases through T-HgII-T Base Pairing

(2010) Hidehito Urata et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Artificial Genetic Systems: Self-Avoiding DNA in PCR and Multiplexed PCR

(2010) Shuichi Hoshika et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Xenobiology: A new form of life as the ultimate biosafety tool

(2010) Markus Schmidt   BIOESSAYS

Exotic DNAs Made of Nonnatural Bases and Natural Phosphodiester Bonds

(2010) Junya Chiba et al.   CHEMISTRY & BIODIVERSITY

Nucleic Acids with a Six-Membered ‘Carbohydrate’ Mimic in the Backbone

(2010) Piet Herdewijn   CHEMISTRY & BIODIVERSITY

Metal–base pairing in DNA

(2010) Guido H. Clever et al.   COORDINATION CHEMISTRY REVIEWS

Effect of Stalling after Mismatches on the Error Catastrophe in Nonenzymatic Nucleic Acid Replication

(2010) Sudha Rajamani et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A New Unnatural Base Pair System between Fluorophore and Quencher Base Analogues for Nucleic Acid-Based Imaging Technology

(2010) Michiko Kimoto et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Unique Fluorescent Base Analogue for the Expansion of the Genetic Alphabet

(2010) Michiko Kimoto et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An in vitro translation, selection and amplification system for peptide nucleic acids

(2010) Yevgeny Brudno et al.   Nature Chemical Biology

Direct detection of DNA methylation during single-molecule, real-time sequencing

(2010) Benjamin A Flusberg et al.   NATURE METHODS

Differential stability of 2′F-ANA•RNA and ANA•RNA hybrid duplexes: roles of structure, pseudohydrogen bonding, hydration, ion uptake and flexibility

(2010) Jonathan K. Watts et al.   NUCLEIC ACIDS RESEARCH

Expanded Genetic Alphabets in the Polymerase Chain Reaction

(2009) Zunyi Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Polymerase engineering: towards the encoded synthesis of unnatural biopolymers

(2009) David Loakes et al.   CHEMICAL COMMUNICATIONS

Toward Safe Genetically Modified Organisms through the Chemical Diversification of Nucleic Acids

(2009) Piet Herdewijn et al.   CHEMISTRY & BIODIVERSITY

PCR with an Expanded Genetic Alphabet

(2009) Denis A. Malyshev et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Evolving a Polymerase for Hydrophobic Base Analogues

(2009) David Loakes et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Selective Recognition of Unnatural Imidazopyridopyrimidine:Naphthyridine Base Pairs Consisting of Four Hydrogen Bonds by the Klenow Fragment

(2009) Noriaki Minakawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Transcription of an Expanded Genetic Alphabet

(2009) Young Jun Seo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient and Rapid Template-Directed Nucleic Acid Copying Using 2′-Amino-2′,3′-dideoxyribonucleoside−5′-Phosphorimidazolide Monomers

(2009) Jason P. Schrum et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions

(2009) Matthew W. Powner et al.   NATURE

Unnatural imidazopyridopyrimidine:naphthyridine base pairs: selective incorporation and extension reaction by Deep Vent (exo− ) DNA polymerase

(2009) Shintaro Ogata et al.   NUCLEIC ACIDS RESEARCH

The effects of unnatural base pairs and mispairs on DNA duplex stability and solvation

(2009) Gil Tae Hwang et al.   NUCLEIC ACIDS RESEARCH

Phosphoserine aminoacylation of tRNA bearing an unnatural base anticodon

(2008) Ryuya Fukunaga et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

G^C Quartet  A DNA-Inspired Janus-GC Heterocycle: Synthesis, Structural Analysis, and Self-Organization

(2008) Ali Asadi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Potent inhibition of microRNA in vivo without degradation

(2008) Scott Davis et al.   NUCLEIC ACIDS RESEARCH

An unnatural base pair system for efficient PCR amplification and functionalization of DNA molecules

(2008) Michiko Kimoto et al.   NUCLEIC ACIDS RESEARCH