Simultaneously inhibiting undecaprenyl phosphate production and peptidoglycan synthases promotes rapid lysis in Escherichia coli

Regulation of the Peptidoglycan Polymerase Activity of PBP1b by Antagonist Actions of the Core Divisome Proteins FtsBLQ and FtsN

(2019) Adrien Boes et al.   mBio

FtsW is a peptidoglycan polymerase that is functional only in complex with its cognate penicillin-binding protein

(2019) Atsushi Taguchi et al.   Nature Microbiology

Targeting the Nonmevalonate Pathway in Burkholderia cenocepacia Increases Susceptibility to Certain β-Lactam Antibiotics

(2018) Andrea Sass et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A defective undecaprenyl pyrophosphate synthase induces growth and morphological defects that are suppressed by mutations in the isoprenoid pathway of Escherichia coli

(2018) William J. MacCain et al.   JOURNAL OF BACTERIOLOGY

Conserved mechanism of cell-wall synthase regulation revealed by the identification of a new PBP activator inPseudomonas aeruginosa

(2018) Neil G. Greene et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induced conformational changes activate the peptidoglycan synthase PBP1B

(2018) Alexander J. F. Egan et al.   MOLECULAR MICROBIOLOGY

The outer membrane is an essential load-bearing element in Gram-negative bacteria

(2018) Enrique R. Rojas et al.   NATURE

A central role for PBP2 in the activation of peptidoglycan polymerization by the bacterial cell elongation machinery

(2018) Patricia D. A. Rohs et al.   PLoS Genetics

PBP1B Glycosyltransferase and Transpeptidase Activities Play Different Essential Roles during the De Novo Regeneration of Rod Morphology in Escherichia coli

(2017) Dev K. Ranjit et al.   JOURNAL OF BACTERIOLOGY

Persistent bacterial infections and persister cells

(2017) Robert A. Fisher et al.   NATURE REVIEWS MICROBIOLOGY

The mecillinam resistome reveals a role for peptidoglycan endopeptidases in stimulating cell wall synthesis in Escherichia coli

(2017) Ghee Chuan Lai et al.   PLoS Genetics

Interplay between Penicillin-binding proteins and SEDS proteins promotes bacterial cell wall synthesis

(2017) Sophie Leclercq et al.   Scientific Reports

Regulation of bacterial cell wall growth

(2016) Alexander J. F. Egan et al.   FEBS Journal

Interrupting Biosynthesis of O Antigen or the Lipopolysaccharide Core Produces Morphological Defects in Escherichia coli by Sequestering Undecaprenyl Phosphate

(2016) Matthew A. Jorgenson et al.   JOURNAL OF BACTERIOLOGY

SEDS proteins are a widespread family of bacterial cell wall polymerases

(2016) Alexander J. Meeske et al.   NATURE

The EcoCyc database: reflecting new knowledge aboutEscherichia coliK-12

(2016) Ingrid M. Keseler et al.   NUCLEIC ACIDS RESEARCH

Cofactor bypass variants reveal a conformational control mechanism governing cell wall polymerase activity

(2016) Monica Markovski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial cell wall biogenesis is mediated by SEDS and PBP polymerase families functioning semi-autonomously

(2016) Hongbaek Cho et al.   Nature Microbiology

In VitroActivity of Aztreonam-Avibactam against a Global Collection of Gram-Negative Pathogens from 2012 and 2013

(2015) Douglas J. Biedenbach et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Cell Growth of Wall-Free L-Form Bacteria Is Limited by Oxidative Damage

(2015) Yoshikazu Kawai et al.   CURRENT BIOLOGY

Dead-end intermediates in the enterobacterial common antigen pathway induce morphological defects inEscherichia coliby competing for undecaprenyl phosphate

(2015) Matthew A. Jorgenson et al.   MOLECULAR MICROBIOLOGY

Bacterial SPOR domains are recruited to septal peptidoglycan by binding to glycan strands that lack stem peptides

(2015) Atsushi Yahashiri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthase

(2015) Maya A. Farha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preliminary Study of Colistin versus Colistin plus Fosfomycin for Treatment of Carbapenem-Resistant Acinetobacter baumannii Infections

(2014) Rujipas Sirijatuphat et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Beta-Lactam Antibiotics Induce a Lethal Malfunctioning of the Bacterial Cell Wall Synthesis Machinery

(2014) Hongbaek Cho et al.   CELL

Differential Requirement for PBP1a and PBP1b inIn VivoandIn VitroFitness of Vibrio cholerae

(2014) Tobias Dörr et al.   INFECTION AND IMMUNITY

Outer-membrane lipoprotein LpoB spans the periplasm to stimulate the peptidoglycan synthase PBP1B

(2014) A. J. F. Egan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MurJ is the flippase of lipid-linked precursors for peptidoglycan biogenesis

(2014) L.-T. Sham et al.   SCIENCE

A Genome-Wide Screen for Bacterial Envelope Biogenesis Mutants Identifies a Novel Factor Involved in Cell Wall Precursor Metabolism

(2014) Catherine Paradis-Bleau et al.   PLoS Genetics

The Rcs Stress Response and Accessory Envelope Proteins Are Required for De Novo Generation of Cell Shape in Escherichia coli

(2013) D. K. Ranjit et al.   JOURNAL OF BACTERIOLOGY

Viable screening targets related to the bacterial cell wall

(2012) Lynn L. Silver   Annals of the New York Academy of Sciences

Cooperativity of peptidoglycan synthases active in bacterial cell elongation

(2012) Manuel Banzhaf et al.   MOLECULAR MICROBIOLOGY

Three redundant murein endopeptidases catalyse an essential cleavage step in peptidoglycan synthesis ofEscherichia coliK12

(2012) Santosh Kumar Singh et al.   MOLECULAR MICROBIOLOGY

A conformational switch controls cell wall-remodelling enzymes required for bacterial cell division

(2012) Desirée C. Yang et al.   MOLECULAR MICROBIOLOGY

EcoGene 3.0

(2012) Jindan Zhou et al.   NUCLEIC ACIDS RESEARCH

A Fail-Safe Mechanism in the Septal Ring Assembly Pathway Generated by the Sequential Recruitment of Cell Separation Amidases and Their Activators

(2011) N. T. Peters et al.   JOURNAL OF BACTERIOLOGY

From the regulation of peptidoglycan synthesis to bacterial growth and morphology

(2011) Athanasios Typas et al.   NATURE REVIEWS MICROBIOLOGY

Direct Measurement of Cell Wall Stress Stiffening and Turgor Pressure in Live Bacterial Cells

(2011) Yi Deng et al.   PHYSICAL REVIEW LETTERS

Lipoprotein Cofactors Located in the Outer Membrane Activate Bacterial Cell Wall Polymerases

(2010) Catherine Paradis-Bleau et al.   CELL

Regulation of Peptidoglycan Synthesis by Outer-Membrane Proteins

(2010) Athanasios Typas et al.   CELL

Cellular Heterogeneity: Do Differences Make a Difference?

(2010) Steven J. Altschuler et al.   CELL

Phenotypic Landscape of a Bacterial Cell

(2010) Robert J. Nichols et al.   CELL

Daughter cell separation is controlled by cytokinetic ring-activated cell wall hydrolysis

(2010) Tsuyoshi Uehara et al.   EMBO JOURNAL

An oldie but a goodie – cell wall biosynthesis as antibiotic target pathway

(2009) Tanja Schneider et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Self-Enhanced Accumulation of FtsN at Division Sites and Roles for Other Proteins with a SPOR Domain (DamX, DedD, and RlpA) in Escherichia coli Cell Constriction

(2009) M. A. Gerding et al.   JOURNAL OF BACTERIOLOGY

LytM-Domain Factors Are Required for Daughter Cell Separation and Rapid Ampicillin-Induced Lysis in Escherichia coli

(2009) T. Uehara et al.   JOURNAL OF BACTERIOLOGY

Rapid  -lactam-induced lysis requires successful assembly of the cell division machinery

(2009) H. S. Chung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA