Inhibition of FASN suppresses the malignant biological behavior of non-small cell lung cancer cells via deregulating glucose metabolism and AKT/ERK pathway

Epistructured catechins, EGCG and EC facilitate apoptosis induction through targeting de novo lipogenesis pathway in HepG2 cells

(2018) Phuriwat Khiewkamrop et al.   Cancer Cell International

Fatty Acid Synthase Is a Therapeutic Target in Mutant KRAS Lung Cancer

(2017) C. Bartolacci et al.   Journal of Thoracic Oncology

Metabolic reprogramming and tolerance during sepsis-induced AKI

(2017) Hernando Gómez et al.   Nature Reviews Nephrology

Fatty acid synthase – Modern tumor cell biology insights into a classical oncology target

(2017) Douglas Buckley et al.   PHARMACOLOGY & THERAPEUTICS

Lipid Metabolism and Lipid Droplets in Pancreatic Cancer and Stellate Cells

(2017) Yoshiaki Sunami et al.   Cancers

Activated mutant forms of PIK3CA cooperate with RasV12 or c-Met to induce liver tumour formation in mice via AKT2/mTORC1 cascade

(2016) Chunmei Wang et al.   LIVER INTERNATIONAL

Lipid metabolic reprogramming in cancer cells

(2016) S Beloribi-Djefaflia et al.   Oncogenesis

Loss of fatty acid synthase suppresses the malignant phenotype of colorectal cancer cells by down-regulating energy metabolism and mTOR signaling pathway

(2015) Ligong Chang et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Global Gene Deregulations inFASNSilenced Retinoblastoma Cancer Cells: Molecular and Clinico-Pathological Correlations

(2015) Manoharan Sangeetha et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Non-small-cell lung cancer

(2015) Cesare Gridelli et al.   Nature Reviews Disease Primers

Cancer cell-associated fatty acid synthase activates endothelial cells and promotes angiogenesis in colorectal cancer

(2014) Yekaterina Y. Zaytseva et al.   CARCINOGENESIS

Expressions of fatty acid synthase and HER2 are correlated with poor prognosis of ovarian cancer

(2014) Yunlang Cai et al.   MEDICAL ONCOLOGY

Alpha-2-Glycoprotein 1(AZGP1) Regulates Biological Behaviors of LoVo Cells by Down-Regulating mTOR Signaling Pathway and Endogenous Fatty Acid Synthesis

(2014) Ligong Chang et al.   PLoS One

The Warburg effect version 2.0: Metabolic reprogramming of cancer stem cells

(2013) JAVIER MENENDEZ et al.   CELL CYCLE

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

Inhibition of Fatty Acid Synthase Attenuates CD44-Associated Signaling and Reduces Metastasis in Colorectal Cancer

(2012) Y. Y. Zaytseva et al.   CANCER RESEARCH

Fatty Acid Synthase Regulates Proliferation and Migration of Colorectal Cancer Cells Via HER2-PI3K/Akt Signaling Pathway

(2012) Nan Li et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Blockade of Fatty Acid Synthase Triggers Significant Apoptosis in Mantle Cell Lymphoma

(2012) Pascal Gelebart et al.   PLoS One

Dysregulation of fatty acid synthesis and glycolysis in non-Hodgkin lymphoma

(2012) A. P. Bhatt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PI3K/AKT/mTOR Pathway in Angiogenesis

(2011) Jayashree Karar et al.   Frontiers in Molecular Neuroscience

Caveolin-1 interacts with a lipid raft-associated population of fatty acid synthase

(2010) Dolores Di Vizio et al.   CELL CYCLE

Periplocin Inhibits Growth of Lung Cancer in vitro and in vivo by Blocking AKT/ERK Signaling Pathways

(2010) Ze J. Lu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Glutamine Uptake and Metabolism Are Coordinately Regulated by ERK/MAPK during T Lymphocyte Activation

(2010) E. L. Carr et al.   JOURNAL OF IMMUNOLOGY

AZGP1 Autoantibody Predicts Survival and Histone Deacetylase Inhibitors Increase Expression in Lung Adenocarcinoma

(2010) Daniel L. Albertus et al.   Journal of Thoracic Oncology