Tumor microenvironment as the “regulator” and “target” for gene therapy
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Title
Tumor microenvironment as the “regulator” and “target” for gene therapy
Authors
Keywords
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Journal
JOURNAL OF GENE MEDICINE
Volume -, Issue -, Pages e3088
Publisher
Wiley
Online
2019-04-02
DOI
10.1002/jgm.3088
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Note: Only part of the references are listed.- Reactive Oxygen Species-Biodegradable Gene Carrier for the Targeting Therapy of Breast Cancer
- (2018) Chunhui Ruan et al. ACS Applied Materials & Interfaces
- In situ dual-crosslinked nanoparticles for tumor targeting gene delivery
- (2018) Ying Zhang et al. Acta Biomaterialia
- Simultaneous Fenton-like Ion Delivery and Glutathione Depletion by MnO2 -Based Nanoagent to Enhance Chemodynamic Therapy
- (2018) Li-Sen Lin et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Enzyme-Responsive Charge-Reversal Polymer-Mediated Effective Gene Therapy for Intraperitoneal Tumors
- (2018) Nasha Qiu et al. BIOMACROMOLECULES
- Highly enhanced cancer immunotherapy by combining nanovaccine with hyaluronidase
- (2018) Xiuwen Guan et al. BIOMATERIALS
- Targeting death receptors for drug-resistant cancer therapy: Codelivery of pTRAIL and monensin using dual-targeting and stimuli-responsive self-assembling nanocomposites
- (2018) Fan Xu et al. BIOMATERIALS
- Dual-responsive polyplexes with enhanced disassembly and endosomal escape for efficient delivery of siRNA
- (2018) Jia Zhu et al. BIOMATERIALS
- TGF-β Inhibition and Immunotherapy: Checkmate
- (2018) Karuna Ganesh et al. IMMUNITY
- Promoter polymorphisms in TGFB1 and IL10 genes influence tumor dendritic cells infiltration, development and prognosis of colorectal cancer
- (2018) Maya Gulubova et al. JOURNAL OF GENE MEDICINE
- Disulfide bond based polymeric drug carriers for cancer chemotherapy and relevant redox environments in mammals
- (2018) Pei Zhang et al. MEDICINAL RESEARCH REVIEWS
- Versatile types of hydroxyl-rich polycationic systems via O -heterocyclic ring-opening reactions: From strategic design to nucleic acid delivery applications
- (2018) Fu-Jian Xu PROGRESS IN POLYMER SCIENCE
- Synergistic and low adverse effect cancer immunotherapy by immunogenic chemotherapy and locally expressed PD-L1 trap
- (2018) Wantong Song et al. Nature Communications
- Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2016
- (2018) et al. JAMA Oncology
- Immune Adjuvant Targeting Micelles Allow Efficient Dendritic Cell Migration to Lymph Nodes for Enhanced Cellular Immunity
- (2018) Xiqin Yang et al. ACS Applied Materials & Interfaces
- Molecular Strings Significantly Improved the Gene Transfection Efficiency of Polycations
- (2018) Huapan Fang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A multi-functional macrophage and tumor targeting gene delivery system for the regulation of macrophage polarity and reversal of cancer immunoresistance
- (2018) Xiao-Yan He et al. Nanoscale
- TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells
- (2018) Sanjeev Mariathasan et al. NATURE
- Treatment with mRNA coding for the necroptosis mediator MLKL induces antitumor immunity directed against neo-epitopes
- (2018) Lien Van Hoecke et al. Nature Communications
- Versatile Types of Organic/Inorganic Nanohybrids: From Strategic Design to Biomedical Applications
- (2018) Nana Zhao et al. CHEMICAL REVIEWS
- Efficient PD-L1 gene silence promoted by hyaluronidase for cancer immunotherapy
- (2018) Xiuwen Guan et al. JOURNAL OF CONTROLLED RELEASE
- In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment
- (2018) Qian Chen et al. Nature Nanotechnology
- Cell death and immunity in cancer: From danger signals to mimicry of pathogen defense responses
- (2017) Abhishek D. Garg et al. IMMUNOLOGICAL REVIEWS
- Targeting ETS1 with RNAi-based supramolecular nanoassemblies for multidrug-resistant breast cancer therapy
- (2017) Min Wu et al. JOURNAL OF CONTROLLED RELEASE
- Stent-mediated gene and drug delivery for cardiovascular disease and cancer: A brief insight
- (2017) Akshaya Krishnagopal et al. JOURNAL OF GENE MEDICINE
- Elements of cancer immunity and the cancer–immune set point
- (2017) Daniel S. Chen et al. NATURE
- Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade
- (2017) Dung T. Le et al. SCIENCE
- Recent progress in cationic polymeric gene carriers for cancer therapy
- (2017) Caina Xu et al. Science China-Chemistry
- Stimuli-Responsive Polymeric Nanocarriers for Efficient Gene Delivery
- (2017) Yingqin Li et al. Topics in Current Chemistry
- Reactive oxygen species (ROS)-responsive nanomedicine for RNAi-based cancer therapy
- (2017) Yang Li et al. Nanoscale
- Synergistic Transcutaneous Immunotherapy Enhances Antitumor Immune Responses through Delivery of Checkpoint Inhibitors
- (2016) Yanqi Ye et al. ACS Nano
- Ultra-pH-Responsive and Tumor-Penetrating Nanoplatform for Targeted siRNA Delivery with Robust Anti-Cancer Efficacy
- (2016) Xiaoding Xu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Immunogenic versus tolerogenic phagocytosis during anticancer therapy: mechanisms and clinical translation
- (2016) A D Garg et al. CELL DEATH AND DIFFERENTIATION
- Self-assembled ternary complexes stabilized with hyaluronic acid-green tea catechin conjugates for targeted gene delivery
- (2016) Kun Liang et al. JOURNAL OF CONTROLLED RELEASE
- Gene delivery and immunomodulatory effects of plasmid DNA associated with Branched Amphiphilic Peptide Capsules
- (2016) L.A. Avila et al. JOURNAL OF CONTROLLED RELEASE
- Reactive Oxygen Species (ROS) Responsive Polymers for Biomedical Applications
- (2016) Qinghua Xu et al. MACROMOLECULAR BIOSCIENCE
- Acid-Activatable Versatile Micelleplexes for PD-L1 Blockade-Enhanced Cancer Photodynamic Immunotherapy
- (2016) Dangge Wang et al. NANO LETTERS
- Ultrasensitive pH Triggered Charge/Size Dual-Rebound Gene Delivery System
- (2016) Xiuwen Guan et al. NANO LETTERS
- Reactive-Oxygen-Species-Responsive Drug Delivery Systems: Promises and Challenges
- (2016) Gurusamy Saravanakumar et al. Advanced Science
- Production and clinical development of nanoparticles for gene delivery
- (2016) Jie Chen et al. Molecular Therapy-Methods & Clinical Development
- Codelivery of Antitumor Drug and Gene by a pH-Sensitive Charge-Conversion System
- (2015) Xiuwen Guan et al. ACS Applied Materials & Interfaces
- Charge-conversional zwitterionic copolymer as pH-sensitive shielding system for effective tumor treatment
- (2015) Jie Chen et al. Acta Biomaterialia
- Fusogenic Reactive Oxygen Species Triggered Charge-Reversal Vector for Effective Gene Delivery
- (2015) Xin Liu et al. ADVANCED MATERIALS
- Viral Vectors for Gene Therapy: Translational and Clinical Outlook
- (2015) Melissa A. Kotterman et al. Annual Review of Biomedical Engineering
- Co-delivery of doxorubicin and tumor-suppressing p53 gene using a POSS-based star-shaped polymer for cancer therapy
- (2015) Yongmao Li et al. BIOMATERIALS
- Surface-Engineered Dendrimers in Gene Delivery
- (2015) Jiepin Yang et al. CHEMICAL REVIEWS
- Regulation of Signal Transduction by Reactive Oxygen Species in the Cardiovascular System
- (2015) D. I. Brown et al. CIRCULATION RESEARCH
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- A Collaborative Assembly Strategy for Tumor-Targeted siRNA Delivery
- (2015) Qiong Sun et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Gene therapy returns to centre stage
- (2015) Luigi Naldini NATURE
- A KALA-modified lipid nanoparticle containing CpG-free plasmid DNA as a potential DNA vaccine carrier for antigen presentation and as an immune-stimulative adjuvant
- (2015) Naoya Miura et al. NUCLEIC ACIDS RESEARCH
- The future of immune checkpoint therapy
- (2015) P. Sharma et al. SCIENCE
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- (2015) Caina Xu et al. Small
- Nanoparticle-Delivered Transforming Growth Factor-β siRNA Enhances Vaccination against Advanced Melanoma by Modifying Tumor Microenvironment
- (2014) Zhenghong Xu et al. ACS Nano
- Cationic Vesicles Based on Amphiphilic Pillar[5]arene Capped with Ferrocenium: A Redox-Responsive System for Drug/siRNA Co-Delivery
- (2014) Yincheng Chang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Hyaluronic acid-chitosan nanoparticles for co-delivery of MiR-34a and doxorubicin in therapy against triple negative breast cancer
- (2014) Xiongwei Deng et al. BIOMATERIALS
- A novel gene therapy vector based on hyaluronic acid and solid lipid nanoparticles for ocular diseases
- (2014) Paola Stephanie Apaolaza et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Mixed Lineage Kinase Domain-like Protein MLKL Causes Necrotic Membrane Disruption upon Phosphorylation by RIP3
- (2014) Huayi Wang et al. MOLECULAR CELL
- Structure-based programming of lymph-node targeting in molecular vaccines
- (2014) Haipeng Liu et al. NATURE
- Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery
- (2014) Vladimir P. Torchilin NATURE REVIEWS DRUG DISCOVERY
- Non-viral vectors for gene-based therapy
- (2014) Hao Yin et al. NATURE REVIEWS GENETICS
- Tumor-Associated Macrophages as Major Players in the Tumor Microenvironment
- (2014) Theerawut Chanmee et al. Cancers
- A Reactive Oxygen Species (ROS)-Responsive Polymer for Safe, Efficient, and Targeted Gene Delivery in Cancer Cells
- (2013) Min Suk Shim et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- PEG-sheddable polyplex micelles as smart gene carriers based on MMP-cleavable peptide-linked block copolymers
- (2013) Junjie Li et al. CHEMICAL COMMUNICATIONS
- Multifaceted Roles of Disulfide Bonds. Peptides as Therapeutics
- (2013) Miriam Góngora-Benítez et al. CHEMICAL REVIEWS
- Materials based tumor immunotherapy vaccines
- (2013) Weiwei Aileen Li et al. CURRENT OPINION IN IMMUNOLOGY
- pH-responsive zwitterionic copolypeptides as charge conversional shielding system for gene carriers
- (2013) Huayu Tian et al. JOURNAL OF CONTROLLED RELEASE
- Cytokine patterns in patients with cancer: a systematic review
- (2013) Bodo E Lippitz LANCET ONCOLOGY
- Adjuvant treatments for resected pancreatic adenocarcinoma: a systematic review and network meta-analysis
- (2013) Wei-Chih Liao et al. LANCET ONCOLOGY
- Stimuli-responsive nanocarriers for drug delivery
- (2013) Simona Mura et al. NATURE MATERIALS
- Current trends in separation of plasmid DNA vaccines: A review
- (2012) Ashraf Ghanem et al. ANALYTICA CHIMICA ACTA
- Hydrophobic poly (amino acid) modified PEI mediated delivery of rev-casp-3 for cancer therapy
- (2012) Chunling Fu et al. BIOMATERIALS
- Inhibition of tumor angiogenesis and growth by nanoparticle-mediated p53 gene therapy in mice
- (2012) S Prabha et al. CANCER GENE THERAPY
- Tumor microenvironment and oxidative stress: involvement in metabolic reprogramming and chemo-resistance of prostate cancer cells
- (2012) M.L. Taddei et al. FREE RADICAL BIOLOGY AND MEDICINE
- In Vivo Gene Delivery by Nonviral Vectors: Overcoming Hurdles?
- (2012) Yuan Zhang et al. MOLECULAR THERAPY
- Combination gene therapy using VEGF-shRNA and fusion suicide gene yCDglyTK inhibits gastric carcinoma growth
- (2011) Ting Liu et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- CpG DNA as a vaccine adjuvant
- (2011) Christian Bode et al. Expert Review of Vaccines
- Novel hyaluronic acid–chitosan nanoparticles as non-viral gene delivery vectors targeting osteoarthritis
- (2011) Hua-Ding Lu et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Glutathione-responsive nano-vehicles as a promising platform for targeted intracellular drug and gene delivery
- (2011) Ru Cheng et al. JOURNAL OF CONTROLLED RELEASE
- Enhancement of dendritic cells transfection in vivo and of vaccination against B16F10 melanoma with mannosylated histidylated lipopolyplexes loaded with tumor antigen messenger RNA
- (2011) Federico Perche et al. Nanomedicine-Nanotechnology Biology and Medicine
- Tumor delivery of macromolecular drugs based on the EPR effect
- (2010) Vladimir Torchilin ADVANCED DRUG DELIVERY REVIEWS
- Polyion complex stability and gene silencing efficiency with a siRNA-grafted polymer delivery system
- (2010) Hiroyasu Takemoto et al. BIOMATERIALS
- The synergistic effect of hierarchical assemblies of siRNA and chemotherapeutic drugs co-delivered into hepatic cancer cells
- (2010) Nuo Cao et al. BIOMATERIALS
- Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
- (2010) Kai Kessenbrock et al. CELL
- Gene silencing efficiency of siRNA-PEG conjugates: Effect of PEGylation site and PEG molecular weight
- (2010) Sooyeon Jung et al. JOURNAL OF CONTROLLED RELEASE
- Chemokine Expression in Melanoma Metastases Associated with CD8+ T-Cell Recruitment
- (2009) H. Harlin et al. CANCER RESEARCH
- p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug
- (2009) Shu-Ping Wang et al. NATURE CELL BIOLOGY
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Gene delivery to dendritic cells mediated by complexes of lipoplexes and pH-sensitive fusogenic polymer-modified liposomes
- (2008) Eiji Yuba et al. JOURNAL OF CONTROLLED RELEASE
- Recent progress in tumor pH targeting nanotechnology
- (2008) Eun Seong Lee et al. JOURNAL OF CONTROLLED RELEASE
- A review of stimuli-responsive nanocarriers for drug and gene delivery
- (2008) Srinivas Ganta et al. JOURNAL OF CONTROLLED RELEASE
- The tumor microenvironment and its role in promoting tumor growth
- (2008) T L Whiteside ONCOGENE
- The BCL-2 protein family: opposing activities that mediate cell death
- (2007) Richard J. Youle et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
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