Spatial control of oxygen delivery to three‐dimensional cultures alters cancer cell growth and gene expression

Review: Microfluidics technologies for blood-based cancer liquid biopsies

(2018) Yuxi Sun et al.   ANALYTICA CHIMICA ACTA

Limitations of oxygen delivery to cells in culture: An underappreciated problem in basic and translational research

(2017) Trenton L. Place et al.   FREE RADICAL BIOLOGY AND MEDICINE

Organ-on-a-chip devices advance to market

(2017) Boyang Zhang et al.   LAB ON A CHIP

Quantification of hypoxia-related gene expression as a potential approach for clinical outcome prediction in breast cancer

(2017) Abderrahim El Guerrab et al.   PLoS One

A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle

(2017) Shuo Xiao et al.   Nature Communications

Rapid Generation and Detection of Biomimetic Oxygen Concentration Gradients In Vitro

(2017) Daud H. Khan et al.   Scientific Reports

Hypoxia enhances angiogenesis in an adipose-derived stromal cell/endothelial cell co-culture 3D gel model

(2016) Qiang Xie et al.   CELL PROLIFERATION

Comparison of cancer cells in 2D vs 3D culture reveals differences in AKT–mTOR–S6K signaling and drug responses

(2016) Angelika Riedl et al.   JOURNAL OF CELL SCIENCE

Intratumoral oxygen gradients mediate sarcoma cell invasion

(2016) Daniel M. Lewis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of hypoxia and necrosis in multicellular tumor spheroids is associated with resistance to chemotherapy treatment

(2016) Silvio Däster et al.   Oncotarget

Spatial regulation of controlled bioactive factor delivery for bone tissue engineering

(2015) Julia E. Samorezov et al.   ADVANCED DRUG DELIVERY REVIEWS

Tissue matrix arrays for high-throughput screening and systems analysis of cell function

(2015) Vince Z Beachley et al.   NATURE METHODS

Designing a Microfluidic Device with Integrated Ratiometric Oxygen Sensors for the Long-Term Control and Monitoring of Chronic and Cyclic Hypoxia

(2015) Samantha Grist et al.   SENSORS

Simultaneous or Sequential Orthogonal Gradient Formation in a 3D Cell Culture Microfluidic Platform

(2015) Sebastien G. M. Uzel et al.   Small

Three-Dimensional Cell Culture Systems and Their Applications in Drug Discovery and Cell-Based Biosensors

(2014) Rasheena Edmondson et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Oxygen control with microfluidics

(2014) Martin D. Brennan et al.   LAB ON A CHIP

3D Cultures of Prostate Cancer Cells Cultured in a Novel High-Throughput Culture Platform Are More Resistant to Chemotherapeutics Compared to Cells Cultured in Monolayer

(2014) Karen F. Chambers et al.   PLoS One

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Microfabricated polymeric vessel mimetics for 3-D cancer cell culture

(2013) Ashley A. Jaeger et al.   BIOMATERIALS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

In vitro microvessels for the study of angiogenesis and thrombosis

(2012) Y. Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The physiological performance of a three-dimensional model that mimics the microenvironment of the small intestine

(2011) Jacqueline Pusch et al.   BIOMATERIALS

REVIGO Summarizes and Visualizes Long Lists of Gene Ontology Terms

(2011) Fran Supek et al.   PLoS One

The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype

(2010) John M. Heddleston et al.   CELL CYCLE

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

Gene ontology analysis for RNA-seq: accounting for selection bias

(2010) Matthew D Young et al.   GENOME BIOLOGY

A scaling normalization method for differential expression analysis of RNA-seq data

(2010) Mark D Robinson et al.   GENOME BIOLOGY

A Dual-Fluorescence High-Throughput Cell Line System for Probing Multidrug Resistance

(2009) Kyle R. Brimacombe et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Generation of oxygen gradients with arbitrary shapes in a microfluidic device

(2009) Micha Adler et al.   LAB ON A CHIP