ERK1/2 phosphorylates HIF-2α and regulates its activity by controlling its CRM1-dependent nuclear shuttling

Mitogen-Activated Protein Kinases and Hypoxic/Ischemic Nephropathy

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Mortalin-mediated and ERK-controlled targeting of HIF-1α to mitochondria confers resistance to apoptosis under hypoxia

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HIF-2α phosphorylation by CK1δ promotes erythropoietin secretion in liver cancer cells under hypoxia

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Targeting renal cell carcinoma with a HIF-2 antagonist

(2016) Wenfang Chen et al.   NATURE

Proteogenomics connects somatic mutations to signalling in breast cancer

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Hypoxic control of metastasis

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Compromised MAPK signaling in human diseases: an update

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The emerging role of hypoxia-inducible factor-2 involved in chemo/radioresistance in solid tumors

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Pharmacological HIF2α inhibition improves VHL disease–associated phenotypes in zebrafish model

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Mitogen-activated protein kinase signaling pathway and invasion and metastasis of gastric cancer

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Cobalt stimulates HIF-1-dependent but inhibits HIF-2-dependent gene expression in liver cancer cells

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Upstream Stimulatory Factor 2 and Hypoxia-Inducible Factor 2  (HIF2 ) Cooperatively Activate HIF2 Target Genes during Hypoxia

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An oxygen-regulated switch in the protein synthesis machinery

(2012) James Uniacke et al.   NATURE

ERK1/2 MAP kinases: Structure, function, and regulation

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Mammalian MAPK Signal Transduction Pathways Activated by Stress and Inflammation: A 10-Year Update

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Passing the baton: the HIF switch

(2012) Mei Yee Koh et al.   TRENDS IN BIOCHEMICAL SCIENCES

Hypoxia and hypoxia inducible factors: Diverse roles in liver diseases

(2011) Bharath Nath et al.   HEPATOLOGY

Oxygen Sensing, Homeostasis, and Disease

(2011) Gregg L. Semenza   NEW ENGLAND JOURNAL OF MEDICINE

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Hypoxia-Inducible Factors and the Response to Hypoxic Stress

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How does PKMζ maintain long-term memory?

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Biology of hypoxia-inducible factor-2α in development and disease

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Atypical CRM1-dependent Nuclear Export Signal Mediates Regulation of Hypoxia-inducible Factor-1α by MAPK

(2008) Ilias Mylonis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

(2008) William G. Kaelin et al.   MOLECULAR CELL