Crystal Structure of VapBC-1 from Nontypeable Haemophilus influenzae and the Effect of PIN Domain Mutations on Survival during Infection

Autoregulation and Virulence Control by the Toxin-Antitoxin System SavRS in Staphylococcus aureus

(2018) Wen Wen et al.   INFECTION AND IMMUNITY

System-Wide Analysis Unravels the Differential Regulation and In Vivo Essentiality of Virulence-Associated Proteins B and C Toxin-Antitoxin Systems of Mycobacterium tuberculosis

(2018) Sakshi Agarwal et al.   JOURNAL OF INFECTIOUS DISEASES

Single nucleotide polymorphisms of Beijing lineage Mycobacterium tuberculosis toxin-antitoxin system genes: Their role in the changes of protein activity and evolution

(2018) M.V. Zaychikova et al.   TUBERCULOSIS

Structural, functional and biological insights into the role of Mycobacterium tuberculosis VapBC11 toxin–antitoxin system: targeting a tRNase to tackle mycobacterial adaptation

(2018) Amar Deep et al.   NUCLEIC ACIDS RESEARCH

Crystal structure of Mycobacterium tuberculosis VapC20 toxin and its interactions with cognate antitoxin, VapB20, suggest a model for toxin-antitoxin assembly

(2017) Amar Deep et al.   FEBS Journal

Structural conservation of the PIN domain active site across all domains of life

(2017) M. Senissar et al.   PROTEIN SCIENCE

Toxins of Prokaryotic Toxin-Antitoxin Systems with Sequence-Specific Endoribonuclease Activity

(2017) Hisako Masuda et al.   Toxins

Wake me when it’s over – Bacterial toxin–antitoxin proteins and induced dormancy

(2016) Nathan P Coussens et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Structural analysis of the active site architecture of the VapC toxin fromShigella flexneri

(2016) Kehan Xu et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Toxin-Antitoxin Systems in Clinical Pathogens

(2016) Laura Fernández-García et al.   Toxins

MoRDa, an automatic molecular replacement pipeline

(2015) Alexey Vagin et al.   Acta Crystallographica A-Foundation and Advances

Analysis of Non-Typeable Haemophilous influenzae VapC1 Mutations Reveals Structural Features Required for Toxicity and Flexibility in the Active Site

(2014) Brooke Hamilton et al.   PLoS One

A Bacterial Toxin Inhibits DNA Replication Elongation through a Direct Interaction with the β Sliding Clamp

(2013) Christopher D. Aakre et al.   MOLECULAR CELL

Toxin-antitoxin loci vapBC-1 and vapXD contribute to survival and virulence in nontypeable Haemophilus influenzae

(2012) Dabin Ren et al.   BMC MICROBIOLOGY

YeeU enhances the bundling of cytoskeletal polymers of MreB and FtsZ, antagonizing the CbtA (YeeV) toxicity in Escherichia coli

(2012) Hisako Masuda et al.   MOLECULAR MICROBIOLOGY

A new type V toxin-antitoxin system where mRNA for toxin GhoT is cleaved by antitoxin GhoS

(2012) Xiaoxue Wang et al.   Nature Chemical Biology

Regulation of the vapBC-1 Toxin-Antitoxin Locus in Nontypeable Haemophilus influenzae

(2012) Susan D. Cline et al.   PLoS One

Resolving Some Old Problems in Protein Crystallography

(2012) P. Evans   SCIENCE

Linking Crystallographic Model and Data Quality

(2012) P. A. Karplus et al.   SCIENCE

Data processing and analysis with theautoPROCtoolbox

(2011) Clemens Vonrhein et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

An introduction to data reduction: space-group determination, scaling and intensity statistics

(2011) Philip R. Evans   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Toxin-Antitoxin Systems in Bacteria and Archaea

(2011) Yoshihiro Yamaguchi et al.   Annual Review of Genetics

Crystal Structure of the VapBC Toxin–Antitoxin Complex from Shigella flexneri Reveals a Hetero-Octameric DNA-Binding Assembly

(2011) Christian Dienemann et al.   JOURNAL OF MOLECULAR BIOLOGY

A processed noncoding RNA regulates an altruistic bacterial antiviral system

(2011) Tim R Blower et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Diversity of bacterial type II toxin–antitoxin systems: a comprehensive search and functional analysis of novel families

(2011) Raphaël Leplae et al.   NUCLEIC ACIDS RESEARCH

Crystal structure of the DNA-bound VapBC2 antitoxin/toxin pair from Rickettsia felis

(2011) María J. Maté et al.   NUCLEIC ACIDS RESEARCH

Enteric virulence associated protein VapC inhibits translation by cleavage of initiator tRNA

(2011) K. S. Winther et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Novel Mechanism of Programmed Cell Death in Bacteria by Toxin–Antitoxin Systems Corrupts Peptidoglycan Synthesis

(2011) Hannes Mutschler et al.   PLOS BIOLOGY

Use of the EpiAirway Model for Characterizing Long-term Host-pathogen Interactions

(2011) Dabin Ren et al.   Jove-Journal of Visualized Experiments

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Construction of a novel shuttle vector for use in Haemophilus influenzae and H. parainfluenzae

(2010) Esther Robinson et al.   JOURNAL OF MICROBIOLOGICAL METHODS

YeeV is an Escherichia coli toxin that inhibits cell division by targeting the cytoskeleton proteins, FtsZ and MreB

(2010) Qian Tan et al.   MOLECULAR MICROBIOLOGY

The PIN-domain ribonucleases and the prokaryotic VapBC toxin-antitoxin array

(2010) V. L. Arcus et al.   PROTEIN ENGINEERING DESIGN & SELECTION

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Driving Forces of Gyrase Recognition by the Addiction Toxin CcdB

(2009) Mario Simic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification and characterization of a family of toxin-antitoxin systems related to the Enterococcus faecalis plasmid pAD1 par addiction module

(2009) K. E. Weaver et al.   MICROBIOLOGY-SGM

The phage abortive infection system, ToxIN, functions as a protein–RNA toxin–antitoxin pair

(2009) Peter C. Fineran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comprehensive Functional Analysis of Mycobacterium tuberculosis Toxin-Antitoxin Systems: Implications for Pathogenesis, Stress Responses, and Evolution

(2009) Holly R. Ramage et al.   PLoS Genetics

Small Toxic Proteins and the Antisense RNAs That Repress Them

(2008) E. M. Fozo et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7

(2008) Gerrit Langer et al.   Nature Protocols

Bacterial addiction module toxin Doc inhibits translation elongation through its association with the 30S ribosomal subunit

(2008) M. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA