Reverse Erythroblastosis Virus α Antagonism Promotes Homocysteine Catabolism and Ammonia Clearance

Pyroptosis by caspase11/4-gasdermin-D pathway in alcoholic hepatitis in mice and patients

(2018) Elena Khanova et al.   HEPATOLOGY

Urea cycle dysregulation in non-alcoholic fatty liver disease

(2018) Francesco De Chiara et al.   JOURNAL OF HEPATOLOGY

Daytime variation of perioperative myocardial injury in cardiac surgery and its prevention by Rev-Erbα antagonism: a single-centre propensity-matched cohort study and a randomised study

(2018) David Montaigne et al.   LANCET

Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence

(2018) Gabriele Sulli et al.   NATURE

Chronotype and social jetlag influence human circadian clock gene expression

(2018) Masaki Takahashi et al.   Scientific Reports

REV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis

(2018) Shuai Wang et al.   Nature Communications

Fasting Imparts a Switch to Alternative Daily Pathways in Liver and Muscle

(2018) Kenichiro Kinouchi et al.   Cell Reports

Hyperhomocysteinemia activates the aryl hydrocarbon receptor/CD36 pathway to promote hepatic steatosis in mice

(2016) Liu Yao et al.   HEPATOLOGY

The role of feeding rhythm, adrenal hormones and neuronal inputs in synchronizing daily clock gene rhythms in the liver

(2016) Yan Su et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Neurotoxicity of Ammonia

(2016) Simo S. Oja et al.   NEUROCHEMICAL RESEARCH

Melatonin Contributes to the Seasonality of Multiple Sclerosis Relapses

(2015) Mauricio F. Farez et al.   CELL

Interactions Between Nuclear Receptor SHP and FOXA1 Maintain Oscillatory Homocysteine Homeostasis in Mice

(2015) Hiroyuki Tsuchiya et al.   GASTROENTEROLOGY

Homocysteine Induces Collagen I Expression by Downregulating Histone Methyltransferase G9a

(2015) Wenjing Lei et al.   PLoS One

Shifting eating to the circadian rest phase misaligns the peripheral clocks with the master SCN clock and leads to a metabolic syndrome

(2015) Atish Mukherji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Branched-chain amino acids in metabolic signalling and insulin resistance

(2014) Christopher J. Lynch et al.   Nature Reviews Endocrinology

Metabolite elucidation of the Hsp90 inhibitor SNX-2112 using ultraperformance liquid chromatography/quadrupole time-of-flight mass spectrometry (UPLC-QTOF/MS)

(2013) Wei Liu et al.   XENOBIOTICA

Klf15 Orchestrates Circadian Nitrogen Homeostasis

(2012) Darwin Jeyaraj et al.   Cell Metabolism

Rev-erb  and Rev-erb  coordinately protect the circadian clock and normal metabolic function

(2012) A. Bugge et al.   GENES & DEVELOPMENT

Ammonia toxicity to the brain

(2012) Olivier Braissant et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β

(2012) Han Cho et al.   NATURE

High fat diet-induced non alcoholic fatty liver disease in rats is associated with hyperhomocysteinemia caused by down regulation of the transsulphuration pathway

(2011) Elena Bravo et al.   Lipids in Health and Disease

Direct Regulation of CLOCK Expression by REV-ERB

(2011) Christine Crumbley et al.   PLoS One

A Circadian Rhythm Orchestrated by Histone Deacetylase 3 Controls Hepatic Lipid Metabolism

(2011) D. Feng et al.   SCIENCE

Identification of SR8278, a Synthetic Antagonist of the Nuclear Heme Receptor REV-ERB

(2010) Douglas Kojetin et al.   ACS Chemical Biology

Characterization of the Core Mammalian Clock Component, NPAS2, as a REV-ERBα/RORα Target Gene

(2010) Christine Crumbley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amino acids: metabolism, functions, and nutrition

(2009) Guoyao Wu   AMINO ACIDS

REV-ERBα Participates in Circadian SREBP Signaling and Bile Acid Homeostasis

(2009) Gwendal Le Martelot et al.   PLOS BIOLOGY

Murine Models of Hyperhomocysteinemia and Their Vascular Phenotypes

(2008) Sanjana Dayal et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Redundant Function of REV-ERBα and β and Non-Essential Role for Bmal1 Cycling in Transcriptional Regulation of Intracellular Circadian Rhythms

(2008) Andrew C. Liu et al.   PLoS Genetics