Hepatocyte-derived exosomes promote T follicular regulatory cell expansion during hepatitis C virus infection

Virus-Specific CD4+ T Cells Have Functional and Phenotypic Characteristics of Follicular T-Helper Cells in Patients With Acute and Chronic HCV Infections

(2016) Bijan Raziorrouh et al.   GASTROENTEROLOGY

Regulation of chronic inflammatory and immune processes by extracellular vesicles

(2016) Paul D. Robbins et al.   JOURNAL OF CLINICAL INVESTIGATION

Follicular regulatory T cells can be specific for the immunizing antigen and derive from naive T cells

(2016) Meryem Aloulou et al.   Nature Communications

Hepatitis C Virus Infection Induces Autocrine Interferon Signaling by Human Liver Endothelial Cells and Release of Exosomes, Which Inhibits Viral Replication

(2015) Silvia Giugliano et al.   GASTROENTEROLOGY

T follicular helper cells, T follicular regulatory cells and autoimmunity

(2015) Yangyang Zhu et al.   INTERNATIONAL IMMUNOLOGY

CD4+CXCR5+ T cells in chronic HCV infection produce less IL-21, yet are efficient at supporting B cell responses

(2015) Michelle Spaan et al.   JOURNAL OF HEPATOLOGY

Exosomes and their roles in immune regulation and cancer

(2015) David W. Greening et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

T follicular regulatory cells in the regulation of B cell responses

(2015) Peter T. Sage et al.   TRENDS IN IMMUNOLOGY

Follicular regulatory T cells impair follicular T helper cells in HIV and SIV infection

(2015) Brodie Miles et al.   Nature Communications

Hypoxic tumor-derived microvesicles negatively regulate NK cell function by a mechanism involving TGF-β and miR23a transfer

(2015) Guy Berchem et al.   OncoImmunology

HIV-Infected Spleens Present Altered Follicular Helper T Cell (Tfh) Subsets and Skewed B Cell Maturation

(2015) Lucie Colineau et al.   PLoS One

The Coinhibitory Receptor CTLA-4 Controls B Cell Responses by Modulating T Follicular Helper, T Follicular Regulatory, and T Regulatory Cells

(2014) Peter T. Sage et al.   IMMUNITY

TGF-β prevents T follicular helper cell accumulation and B cell autoreactivity

(2014) Mark J. McCarron et al.   JOURNAL OF CLINICAL INVESTIGATION

Increased numbers of CD5+CD19+CD1dhighIL-10+ Bregs, CD4+Foxp3+ Tregs, CD4+CXCR5+Foxp3+ follicular regulatory T (TFR) cells in CHB or CHC patients

(2014) Li Wang et al.   Journal of Translational Medicine

Exosomes from Hepatitis C Infected Patients Transmit HCV Infection and Contain Replication Competent Viral RNA in Complex with Ago2-miR122-HSP90

(2014) Terence N. Bukong et al.   PLoS Pathogens

Emerging concepts in immunity to hepatitis C virus infection

(2013) Hugo R. Rosen   JOURNAL OF CLINICAL INVESTIGATION

Exosome-mediated transmission of hepatitis C virus between human hepatoma Huh7.5 cells

(2013) V. Ramakrishnaiah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Short-Range Exosomal Transfer of Viral RNA from Infected Cells to Plasmacytoid Dendritic Cells Triggers Innate Immunity

(2012) Marlène Dreux et al.   Cell Host & Microbe

HCV-infected hepatocytes drive CD4+CD25+Foxp3+regulatory T-cell development through the Tim-3/Gal-9 pathway

(2012) Xiao J. Ji et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Global epidemiology of hepatitis C virus infection: New estimates of age-specific antibody to HCV seroprevalence

(2012) Khayriyyah Mohd Hanafiah et al.   HEPATOLOGY

Broadly directed virus-specific CD4+T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence

(2012) Julian Schulze zur Wiesch et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Regulatory Role for IL-10 Receptor Signaling in Development and B Cell Help of T Follicular Helper Cells in Mice

(2012) G. Cai et al.   JOURNAL OF IMMUNOLOGY

Human Blood CXCR5+CD4+ T Cells Are Counterparts of T Follicular Cells and Contain Specific Subsets that Differentially Support Antibody Secretion

(2011) Rimpei Morita et al.   IMMUNITY

Regulation of the Germinal Center Reaction by Foxp3+ Follicular Regulatory T Cells

(2011) I. Wollenberg et al.   JOURNAL OF IMMUNOLOGY

Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions

(2011) Yeonseok Chung et al.   NATURE MEDICINE

Foxp3+ follicular regulatory T cells control the germinal center response

(2011) Michelle A Linterman et al.   NATURE MEDICINE

Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity

(2010) Rachel H. McMahan et al.   JOURNAL OF CLINICAL INVESTIGATION

HCV+ Hepatocytes Induce Human Regulatory CD4+ T Cells through the Production of TGF-β

(2010) Caroline H. T. Hall et al.   PLoS One

Abundant numbers of regulatory T cells localize to the liver of chronic hepatitis C infected patients and limit the extent of fibrosis

(2009) Mark A.A. Claassen et al.   JOURNAL OF HEPATOLOGY

Functional Suppression by FoxP3+CD4+CD25highRegulatory T Cells during Acute Hepatitis C Virus Infection

(2007) Susan Smyk‐Pearson et al.   JOURNAL OF INFECTIOUS DISEASES