Isoflurane prevents acquired epilepsy in rat models of temporal lobe epilepsy

Multimodality imaging of blood–brain barrier impairment during epileptogenesis

(2016) Heike Breuer et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Serial Quantitative TSPO-Targeted PET Reveals Peak Microglial Activation up to 2 Weeks After an Epileptogenic Brain Insult

(2016) M. Brackhan et al.   JOURNAL OF NUCLEAR MEDICINE

Infections, inflammation and epilepsy

(2015) Annamaria Vezzani et al.   ACTA NEUROPATHOLOGICA

Isoflurane Ameliorates Acute Lung Injury by Preserving Epithelial Tight Junction Integrity

(2015) Joshua A. Englert et al.   ANESTHESIOLOGY

Effects of isoflurane postconditioning on chronic phase of ischemia–reperfusion heart injury in rats

(2015) Ivan Agnić et al.   CARDIOVASCULAR PATHOLOGY

Factors controlling permeability of the blood–brain barrier

(2015) Mohammed M. A. Almutairi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Albumin induces excitatory synaptogenesis through astrocytic TGF-β/ALK5 signaling in a model of acquired epilepsy following blood–brain barrier dysfunction

(2015) Itai Weissberg et al.   NEUROBIOLOGY OF DISEASE

Brain inflammation in a chronic epilepsy model: Evolving pattern of the translocator protein during epileptogenesis

(2015) Halima Amhaoul et al.   NEUROBIOLOGY OF DISEASE

Analyzing the blood–brain barrier: The benefits of medical imaging in research and clinical practice

(2015) Yoash Chassidim et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Blood–brain barrier dysfunction, seizures and epilepsy

(2015) E.A. van Vliet et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Losartan prevents acquired epilepsy via TGF-β signaling suppression

(2014) Guy Bar-Klein et al.   ANNALS OF NEUROLOGY

Isoflurane Preconditioning Ameliorates Renal Ischemia-Reperfusion Injury through Antiinflammatory and Antiapoptotic Actions in Rats

(2014) Yaoxian Liang et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

sec-Butyl-propylacetamide (SPD) and two of its stereoisomers rapidly terminate paraoxon-induced status epilepticus in rats

(2014) Guy Bar-Klein et al.   EPILEPSIA

18F-GE-180: a novel TSPO radiotracer compared to 11C-R-PK11195 in a preclinical model of stroke

(2014) Hervé Boutin et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Epigenetic Enhancement of Brain-Derived Neurotrophic Factor Signaling Pathway Improves Cognitive Impairments Induced by Isoflurane Exposure in Aged Rats

(2014) MuHuo Ji et al.   MOLECULAR NEUROBIOLOGY

Policy: NIH to balance sex in cell and animal studies

(2014) Janine A. Clayton et al.   NATURE

Rate and extent of leakage of a magnetic resonance contrast agent tend to be lower under isoflurane anesthesia in comparison to halothane in a rat model of embolic stroke

(2014) Francisco J. Bezerra et al.   NEUROLOGICAL RESEARCH

Searching for the Ideal Antiepileptogenic Agent in Experimental Models: Single Treatment Versus Combinatorial Treatment Strategies

(2014) H. Steve White et al.   Neurotherapeutics

Neuroprotective gases – Fantasy or reality for clinical use?

(2014) Jiao Deng et al.   PROGRESS IN NEUROBIOLOGY

Issues related to development of antiepileptogenic therapies

(2013) Asla Pitkänen et al.   EPILEPSIA

New avenues for anti-epileptic drug discovery and development

(2013) Wolfgang Löscher et al.   NATURE REVIEWS DRUG DISCOVERY

Isoflurane on brain inflammation

(2013) Orhan Altay et al.   NEUROBIOLOGY OF DISEASE

Transient Inhibition of TrkB Kinase after Status Epilepticus Prevents Development of Temporal Lobe Epilepsy

(2013) Gumei Liu et al.   NEURON

PET Imaging of Inflammation Biomarkers

(2013) Chenxi Wu et al.   Theranostics

The intrahippocampal kainate model of temporal lobe epilepsy revisited: Epileptogenesis, behavioral and cognitive alterations, pharmacological response, and hippoccampal damage in epileptic rats

(2012) Marta Rattka et al.   EPILEPSY RESEARCH

Isoflurane Protects Against Human Endothelial Cell Apoptosis by Inducing Sphingosine Kinase-1 via ERK MAPK

(2012) Adnan M. Bakar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Isoflurane Induces Endothelial Apoptosis of the Post-Hypoxic Blood-Brain Barrier in a Transdifferentiated Human Umbilical Vein Edothelial Cell Model

(2012) Michael S. Dittmar et al.   PLoS One

TrkB inhibition as a therapeutic target for CNS-related disorders

(2012) Fabien Boulle et al.   PROGRESS IN NEUROBIOLOGY

Isoflurane Attenuates Blood–Brain Barrier Disruption in Ipsilateral Hemisphere After Subarachnoid Hemorrhage in Mice

(2012) Orhan Altay et al.   STROKE

Brain inflammation as a biomarker in epilepsy

(2011) Annamaria Vezzani et al.   Biomarkers in Medicine

Kainic Acid-Induced Neurotoxicity: Targeting Glial Responses and Glia-Derived Cytokines

(2011) Xing-Mei Zhang et al.   Current Neuropharmacology

Brain Infiltration of Leukocytes Contributes to the Pathophysiology of Temporal Lobe Epilepsy

(2011) M. Zattoni et al.   JOURNAL OF NEUROSCIENCE

Mechanisms of epileptogenesis and potential treatment targets

(2011) Asla Pitkänen et al.   LANCET NEUROLOGY

Networking for new drugs

(2011) Claire Ainsworth   NATURE MEDICINE

Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures

(2010) Mattia Maroso et al.   NATURE MEDICINE

Prevention or Modification of Epileptogenesis after Brain Insults: Experimental Approaches and Translational Research

(2010) W. Loscher et al.   PHARMACOLOGICAL REVIEWS

Preventing and treating posttraumatic seizures: The human experience

(2009) Nancy R. Temkin   EPILEPSIA

State of the art: Sedation concepts with volatile anesthetics in critically Ill patients

(2009) Jens Soukup et al.   JOURNAL OF CRITICAL CARE

Neuroprotective effect of volatile anesthetic agents: molecular mechanisms

(2009) Gerald A. Matchett et al.   NEUROLOGICAL RESEARCH

Evaluation ofN-benzyl-N-[11C]methyl-2- (7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamide ([11C]DAC) as a novel translocator protein (18 kDa) radioligand in kainic acid-lesioned rat

(2009) Kazuhiko Yanamoto et al.   SYNAPSE

Seizures in the intrahippocampal kainic acid epilepsy model: characterization using long-term video-EEG monitoring in the rat

(2008) R. Raedt et al.   ACTA NEUROLOGICA SCANDINAVICA

Network pharmacology: the next paradigm in drug discovery

(2008) Andrew L Hopkins   Nature Chemical Biology