Epigenetic Enhancement of Brain-Derived Neurotrophic Factor Signaling Pathway Improves Cognitive Impairments Induced by Isoflurane Exposure in Aged Rats

The Potential of HDAC Inhibitors as Cognitive Enhancers

(2013) Johannes Gräff et al.   Annual Review of Pharmacology and Toxicology

Class I Histone Deacetylase Inhibitor Valproic Acid Reverses Cognitive Deficits in a Mouse Model of Septic Encephalopathy

(2013) Jing Wu et al.   NEUROCHEMICAL RESEARCH

Minocycline Attenuates Cognitive Impairment Induced by Isoflurane Anesthesia in Aged Rats

(2013) Feijuan Kong et al.   PLoS One

Anesthetics isoflurane and desflurane differently affect mitochondrial function, learning, and memory

(2012) Yiying Zhang et al.   ANNALS OF NEUROLOGY

Environmental enrichment attenuates hippocampal neuroinflammation and improves cognitive function during influenza infection

(2012) Heidi A. Jurgens et al.   BRAIN BEHAVIOR AND IMMUNITY

Changes in plasma and cerebrospinal fluid biomarkers in aged patients with early postoperative cognitive dysfunction following total hip-replacement surgery

(2012) Mu-Huo Ji et al.   Journal of Anesthesia

An epigenetic blockade of cognitive functions in the neurodegenerating brain

(2012) Johannes Gräff et al.   NATURE

Isoflurane Selectively Inhibits Distal Mitochondrial Complex I in Caenorhabditis Elegans

(2011) Ernst-Bernhard Kayser et al.   ANESTHESIA AND ANALGESIA

The Effects of Isoflurane and Desflurane on Cognitive Function in Humans

(2011) Bin Zhang et al.   ANESTHESIA AND ANALGESIA

Epigenetic regulation of neurogenesis in the adult mammalian brain

(2011) Jiaqi Sun et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Epigenetic Enhancement of BDNF Signaling Rescues Synaptic Plasticity in Aging

(2011) Y. Zeng et al.   JOURNAL OF NEUROSCIENCE

Isoflurane induces hippocampal cell injury and cognitive impairments in adult rats

(2011) Daowei Lin et al.   NEUROPHARMACOLOGY

Enhancement of LTP in Aged Rats is Dependent on Endogenous BDNF

(2011) Maria J Diógenes et al.   NEUROPSYCHOPHARMACOLOGY

7,8-Dihydroxyflavone, a Small-Molecule TrkB Agonist, Reverses Memory Deficits and BACE1 Elevation in a Mouse Model of Alzheimer's Disease

(2011) Latha Devi et al.   NEUROPSYCHOPHARMACOLOGY

Histone deacetylases as regulators of inflammation and immunity

(2011) Melanie R. Shakespear et al.   TRENDS IN IMMUNOLOGY

Cognitive Function after Major Noncardiac Surgery, Apolipoprotein E4 Genotype, and Biomarkers of Brain Injury

(2010) David L. McDonagh et al.   ANESTHESIOLOGY

Role of interleukin-1β in postoperative cognitive dysfunction

(2010) Mario Cibelli et al.   ANNALS OF NEUROLOGY

Isoflurane Anesthesia Induced Persistent, Progressive Memory Impairment, Caused a Loss of Neural Stem Cells, and Reduced Neurogenesis in Young, but Not Adult, Rodents

(2010) Changlian Zhu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Epigenetics, hippocampal neurogenesis, and neuropsychiatric disorders: Unraveling the genome to understand the mind

(2010) Jenny Hsieh et al.   NEUROBIOLOGY OF DISEASE

Altered Histone Acetylation Is Associated with Age-Dependent Memory Impairment in Mice

(2010) S. Peleg et al.   SCIENCE

Predictors of Cognitive Dysfunction after Major Noncardiac Surgery

(2009) Terri G. Monk et al.   ANESTHESIOLOGY

Long-term Consequences of Postoperative Cognitive Dysfunction

(2009) Jacob Steinmetz et al.   ANESTHESIOLOGY

Effect of Hypercarbia and Isoflurane on Brain Cell Death and Neurocognitive Dysfunction in 7-day-old Rats

(2009) Greg Stratmann et al.   ANESTHESIOLOGY

HDAC2 negatively regulates memory formation and synaptic plasticity

(2009) Ji-Song Guan et al.   NATURE

Epigenetic regulation of nervous system development by DNA methylation and histone deacetylation

(2009) Jessica L. MacDonald et al.   PROGRESS IN NEUROBIOLOGY

Therapeutic application of histone deacetylase inhibitors for central nervous system disorders

(2008) Aleksey G. Kazantsev et al.   NATURE REVIEWS DRUG DISCOVERY