Genetic and epigenetic sex-specific adaptations to endurance exercise

Sex influences DNA methylation and gene expression in human skeletal muscle myoblasts and myotubes

(2019) Cajsa Davegårdh et al.   Stem Cell Research & Therapy

Distance running alters peripheral microRNAs implicated in metabolism, fluid balance, and myosin regulation in a sex-specific manner

(2018) Steven D. Hicks et al.   PHYSIOLOGICAL GENOMICS

Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system

(2018) Julia Ramírez et al.   Nature Communications

Genetic study links components of the autonomous nervous system to heart-rate profile during exercise

(2018) Niek Verweij et al.   Nature Communications

The exercise sex gap and the impact of the estrous cycle on exercise performance in mice

(2018) Aderbal S. Aguiar et al.   Scientific Reports

Epigenetic control of variation and stochasticity in metabolic disease

(2018) Ilaria Panzeri et al.   Molecular Metabolism

A genome-wide search for new imprinted genes in the human placenta identifies DSCAM as the first imprinted gene on chromosome 21

(2018) Laïla Allach El Khattabi et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Microbiome at the Frontier of Personalized Medicine

(2017) Purna C. Kashyap et al.   MAYO CLINIC PROCEEDINGS

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness

(2017) Sara M. Willems et al.   Nature Communications

Epigenetic regulation of skeletal muscle metabolism

(2016) K. F. Howlett et al.   CLINICAL SCIENCE

Sports genetics moving forward: lessons learned from medical research

(2016) C. Mikael Mattsson et al.   PHYSIOLOGICAL GENOMICS

Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females

(2016) Vicent Ribas et al.   Science Translational Medicine

Absence of genomic hypomethylation or regulation of cytosine-modifying enzymes with aging in male and female mice

(2016) Niran Hadad et al.   Epigenetics & Chromatin

Disruption of the Class IIa HDAC Corepressor Complex Increases Energy Expenditure and Lipid Oxidation

(2016) Vidhi Gaur et al.   Cell Reports

Lipids Reprogram Metabolism to Become a Major Carbon Source for Histone Acetylation

(2016) Eoin McDonnell et al.   Cell Reports

The Impact of Endurance Training on Human Skeletal Muscle Memory, Global Isoform Expression and Novel Transcripts

(2016) Maléne E Lindholm et al.   PLoS Genetics

A Comprehensive Analysis of miRNA/isomiR Expression with Gender Difference

(2016) Li Guo et al.   PLoS One

Exercise-associated DNA methylation change in skeletal muscle and the importance of imprinted genes: a bioinformatics meta-analysis

(2015) William M Brown   BRITISH JOURNAL OF SPORTS MEDICINE

Sex-based differences in endurance exercise muscle metabolism: impact on exercise and nutritional strategies to optimize health and performance in women

(2015) Michaela C. Devries   EXPERIMENTAL PHYSIOLOGY

Exercise training and DNA methylation in humans

(2014) S. Voisin et al.   Acta Physiologica

Sex differences in human fatigability: mechanisms and insight to physiological responses

(2014) S. K. Hunter   Acta Physiologica

Meta-analysis of human methylation data for evidence of sex-specific autosomal patterns

(2014) Nina S McCarthy et al.   BMC GENOMICS

An integrative analysis reveals coordinated reprogramming of the epigenome and the transcriptome in human skeletal muscle after training

(2014) Maléne E Lindholm et al.   Epigenetics

Where are all the female participants in Sports and Exercise Medicine research?

(2014) Joseph T. Costello et al.   European Journal of Sport Science

The human skeletal muscle transcriptome: sex differences, alternative splicing, and tissue homogeneity assessed with RNA sequencing

(2014) Malene E. Lindholm et al.   FASEB JOURNAL

Sex Differences in the Developmental Origins of Cardiovascular Disease

(2014) Suttira Intapad et al.   PHYSIOLOGY

Physical Exercise and Epigenetic Modulation: Elucidating Intricate Mechanisms

(2014) Helios Pareja-Galeano et al.   SPORTS MEDICINE

Exercise epigenetics and the fetal origins of disease

(2014) Thomas EW Chalk et al.   Epigenomics

Early de novo DNA methylation and prolonged demethylation in the muscle lineage

(2013) Koji Tsumagari et al.   Epigenetics

MicroRNAs in skeletal muscle biology and exercise adaptation

(2013) Tyler J. Kirby et al.   FREE RADICAL BIOLOGY AND MEDICINE

Regulation of miRNAs in human skeletal muscle following acute endurance exercise and short-term endurance training

(2013) Aaron P. Russell et al.   JOURNAL OF PHYSIOLOGY-LONDON

Genome-Wide Analysis of Chromatin States Reveals Distinct Mechanisms of Sex-Dependent Gene Regulation in Male and Female Mouse Liver

(2013) A. Sugathan et al.   MOLECULAR AND CELLULAR BIOLOGY

The Association of Sport Performance with ACE and ACTN3 Genetic Polymorphisms: A Systematic Review and Meta-Analysis

(2013) Fang Ma et al.   PLoS One

Exercise: Putting Action into Our Epigenome

(2013) Joshua Denham et al.   SPORTS MEDICINE

Toward Exercise as Personalized Medicine

(2013) Thomas W. Buford et al.   SPORTS MEDICINE

Genes for Elite Power and Sprint Performance: ACTN3 Leads the Way

(2013) Nir Eynon et al.   SPORTS MEDICINE

MicroRNAs in skeletal muscle and their regulation with exercise, ageing, and disease

(2013) Evelyn Zacharewicz et al.   Frontiers in Physiology

The genetic component of Brugada syndrome

(2013) Morten W. Nielsen et al.   Frontiers in Physiology

Perilipin family (PLIN) proteins in human skeletal muscle: the effect of sex, obesity, and endurance training

(2012) Sandra J. Peters et al.   Applied Physiology Nutrition and Metabolism

Acute Exercise Remodels Promoter Methylation in Human Skeletal Muscle

(2012) Romain Barrès et al.   Cell Metabolism

Impact of an Exercise Intervention on DNA Methylation in Skeletal Muscle From First-Degree Relatives of Patients With Type 2 Diabetes

(2012) M. D. Nitert et al.   DIABETES

Epigenetic Modifications

(2011) Diane E. Handy et al.   CIRCULATION

Genomic imprinting: recognition and marking of imprinted loci

(2011) Lara K Abramowitz et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The MyomiR Network in Skeletal Muscle Plasticity

(2011) John J. McCarthy   EXERCISE AND SPORT SCIENCES REVIEWS

Different Molecular and Structural Adaptations with Eccentric and Conventional Strength Training in Elderly Men and Women

(2011) Matthias Mueller et al.   GERONTOLOGY

The ACE Gene and Human Performance

(2011) Zudin Puthucheary et al.   SPORTS MEDICINE

Skeletal muscle gene expression in response to resistance exercise: sex specific regulation

(2010) Dongmei Liu et al.   BMC GENOMICS

Sex differences in histone modifications in the neonatal mouse brain

(2010) Houng-Wei Tsai et al.   Epigenetics

Association Between the ACTN3 R577X Polymorphism and Female Endurance Athletes in China

(2010) X. Shang et al.   INTERNATIONAL JOURNAL OF SPORTS MEDICINE

Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans

(2010) James A. Timmons et al.   JOURNAL OF APPLIED PHYSIOLOGY

Histone modifications and exercise adaptations

(2010) Sean L. McGee et al.   JOURNAL OF APPLIED PHYSIOLOGY

Genomic predictors of the maximal O2 uptake response to standardized exercise training programs

(2010) Claude Bouchard et al.   JOURNAL OF APPLIED PHYSIOLOGY

Muscle specific microRNAs are regulated by endurance exercise in human skeletal muscle

(2010) Søren Nielsen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

A Study of the Influence of Sex on Genome Wide Methylation

(2010) Jingyu Liu et al.   PLoS One

Is there a gender difference between ACE gene and race distance?

(2009) Seok-Ki Min et al.   Applied Physiology Nutrition and Metabolism

Non-CpG Methylation of the PGC-1α Promoter through DNMT3B Controls Mitochondrial Density

(2009) Romain Barrès et al.   Cell Metabolism

Systematic analysis of adaptations in aerobic capacity and submaximal energy metabolism provides a unique insight into determinants of human aerobic performance

(2009) Niels B. J. Vollaard et al.   JOURNAL OF APPLIED PHYSIOLOGY

Exercise-induced histone modifications in human skeletal muscle

(2009) Sean L. McGee et al.   JOURNAL OF PHYSIOLOGY-LONDON

ACE Genotype and the Muscle Hypertrophic and Strength Responses to Strength Training

(2009) DAVID E. CHARBONNEAU et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Parental origin of sequence variants associated with complex diseases

(2009) Augustine Kong et al.   NATURE

Physical activity, fitness and fatness: relations to mortality, morbidity and disease risk factors. A systematic review

(2009) M. Fogelholm   Obesity Reviews

Exercise, sex, menstrual cycle phase, and 17β-estradiol influence metabolism-related genes in human skeletal muscle

(2009) Ming-hua H. Fu et al.   PHYSIOLOGICAL GENOMICS

Sex Differences in Global mRNA Content of Human Skeletal Muscle

(2009) Amy C. Maher et al.   PLoS One

The Relationship of DNA Methylation with Age, Gender and Genotype in Twins and Healthy Controls

(2009) Marco P. Boks et al.   PLoS One

CaMK activation during exercise is required for histone hyperacetylation and MEF2A binding at the MEF2 site on the Glut4 gene

(2008) James A. H. Smith et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Sex differences in the developmental origins of hypertension and cardiorenal disease

(2008) Jeffrey S. Gilbert et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Association of the ACTN3 R577X polymorphism with power athlete status in Russians

(2008) Anastasiya M. Druzhevskaya et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Effect of sex differences on human MEF2 regulation during endurance exercise

(2007) Kristian Vissing et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM