Exercise training and DNA methylation in humans

On the presence and role of human gene-body DNA methylation

(2015) Daudi Jjingo et al.   Oncotarget

PGC1  Promoter Methylation in Blood at 5-7 Years Predicts Adiposity From 9 to 14 Years (EarlyBird 50)

(2014) R. Clarke-Harris et al.   DIABETES

Dynamic epigenetic responses to muscle contraction

(2014) Morten Rasmussen et al.   DRUG DISCOVERY TODAY

No effect of weight loss on LINE-1 methylation levels in peripheral blood leukocytes from postmenopausal overweight women

(2014) Catherine Duggan et al.   Obesity

Physical Exercise and Epigenetic Modulation: Elucidating Intricate Mechanisms

(2014) Helios Pareja-Galeano et al.   SPORTS MEDICINE

Can we optimise the exercise training prescription to maximise improvements in mitochondria function and content?

(2013) David J. Bishop et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Recreational and household physical activity at different time points and DNA global methylation

(2013) Alexandra J. White et al.   EUROPEAN JOURNAL OF CANCER

Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm

(2013) B. Zhang et al.   GENOME RESEARCH

Polymorphisms in DNA repair genes, recreational physical activity and breast cancer risk

(2013) Lauren E. McCullough et al.   INTERNATIONAL JOURNAL OF CANCER

Epigenetic regulation of muscle phenotype and adaptation: a potential role in COPD muscle dysfunction

(2013) Esther Barreiro et al.   JOURNAL OF APPLIED PHYSIOLOGY

Association of theMTHFR1298A>C (rs1801131) polymorphism with speed and strength sports in Russian and Polish athletes

(2013) Aleksandra Zarebska et al.   JOURNAL OF SPORTS SCIENCES

Epigenetics in Sports

(2013) Tobias Ehlert et al.   SPORTS MEDICINE

Exercise: Putting Action into Our Epigenome

(2013) Joshua Denham et al.   SPORTS MEDICINE

Genes for Elite Power and Sprint Performance: ACTN3 Leads the Way

(2013) Nir Eynon et al.   SPORTS MEDICINE

A Six Months Exercise Intervention Influences the Genome-wide DNA Methylation Pattern in Human Adipose Tissue

(2013) Tina Rönn et al.   PLoS Genetics

Cancer Genetics and Epigenetics: Two Sides of the Same Coin?

(2012) Jueng Soo You et al.   CANCER CELL

Cancer Epigenetics: From Mechanism to Therapy

(2012) Mark A. Dawson et al.   CELL

Acute Exercise Remodels Promoter Methylation in Human Skeletal Muscle

(2012) Romain Barrès et al.   Cell Metabolism

PGC-1α: a master gene that is hard to master

(2012) Dan Lindholm et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Impact of an Exercise Intervention on DNA Methylation in Skeletal Muscle From First-Degree Relatives of Patients With Type 2 Diabetes

(2012) M. D. Nitert et al.   DIABETES

White blood cell global methylation and IL-6 promoter methylation in association with diet and lifestyle risk factors in a cancer-free population

(2012) Fang Fang Zhang et al.   Epigenetics

Epigenetic Changes in Response to Tai Chi Practice: A Pilot Investigation of DNA Methylation Marks

(2012) Hua Ren et al.   Evidence-based Complementary and Alternative Medicine

The relationship of testosterone and AR CAG repeat genotype with knee extensor muscle function of young and older men

(2012) J.P. Folland et al.   EXPERIMENTAL GERONTOLOGY

Epigenetic modification of liver mitochondrial DNA is associated with histological severity of nonalcoholic fatty liver disease

(2012) Carlos Jose Pirola et al.   GUT

Physical Exercise as an Epigenetic Modulator

(2012) Fabian Sanchis-Gomar et al.   JOURNAL OF STRENGTH AND CONDITIONING RESEARCH

Physical Activity, Biomarkers, and Disease Outcomes in Cancer Survivors: A Systematic Review

(2012) R. Ballard-Barbash et al.   JNCI-Journal of the National Cancer Institute

The influence of metabolic syndrome, physical activity and genotype on catechol-O-methyl transferase promoter-region methylation in schizophrenia

(2012) S A Lott et al.   PHARMACOGENOMICS JOURNAL

The ACTN3 R577X Polymorphism across Three Groups of Elite Male European Athletes

(2012) Nir Eynon et al.   PLoS One

Role of Alpha-actinin-3 in Contractile Properties of Human Single Muscle Fibers: A Case Series Study in Paraplegics

(2012) Siacia Broos et al.   PLoS One

Age-Related Changes in the Global DNA Methylation Profile of Leukocytes Are Linked to Nutrition but Are Not Associated with the MTHFR C677T Genotype or to Functional Capacities

(2012) Marcus V. M. Gomes et al.   PLoS One

Biologic and epigenetic impact of commuting to work by car or using public transportation: A case–control study

(2012) Alfredo Morabia et al.   PREVENTIVE MEDICINE

Physical activity is associated with decreased global DNA methylation in Swedish older individuals

(2012) Karin Luttropp et al.   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION

Active DNA demethylation by Gadd45 and DNA repair

(2012) Christof Niehrs et al.   TRENDS IN CELL BIOLOGY

Alpha-actinin-3 deficiency does not significantly alter oxidative enzyme activity in fast human muscle fibres

(2011) B. Vincent et al.   Acta Physiologica

An acute bout of high-intensity interval training increases the nuclear abundance of PGC-1α and activates mitochondrial biogenesis in human skeletal muscle

(2011) Jonathan P. Little et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

DNA Demethylation Dynamics

(2011) Nidhi Bhutani et al.   CELL

Impact of Physical Activity and Doping on Epigenetic Gene Regulation

(2011) Heidi Schwarzenbach   Drug Testing and Analysis

Physical activity and global genomic DNA methylation in a cancer-free population

(2011) Fang Fang Zhang et al.   Epigenetics

Significant differences in global genomic DNA methylation by gender and race/ethnicity in peripheral blood

(2011) Fang Fang Zhang et al.   Epigenetics

Single and combined influence of ACE and ACTN3 genotypes on muscle phenotypes in octogenarians

(2011) Nuria Garatachea et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Two common genetic variants near nuclear-encoded OXPHOS genes are associated with insulin secretion in vivo

(2011) Anders H Olsson et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Genes and elite athletes: a roadmap for future research

(2011) Nir Eynon et al.   JOURNAL OF PHYSIOLOGY-LONDON

Mitochondrial regulators of fatty acid metabolism reflect metabolic dysfunction in type 2 diabetes mellitus

(2011) Sameer S. Kulkarni et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Neuronal activity modifies the DNA methylation landscape in the adult brain

(2011) Junjie U Guo et al.   NATURE NEUROSCIENCE

Genetic polymorphisms of the enzymes involved in DNA methylation and synthesis in elite athletes

(2011) Ileana Terruzzi et al.   PHYSIOLOGICAL GENOMICS

DNA methyltransferase 1, cytosine methylation, and cytosine hydroxymethylation in mammalian mitochondria

(2011) Lisa S. Shock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The ACE Gene and Human Performance

(2011) Zudin Puthucheary et al.   SPORTS MEDICINE

Analysis of DNA Methylation in a Three-Generation Family Reveals Widespread Genetic Influence on Epigenetic Regulation

(2011) Jason Gertz et al.   PLoS Genetics

Epigenetic control of skeletal muscle fibre type

(2010) K. Baar   Acta Physiologica

Insulin resistance induced by physical inactivity is associated with multiple transcriptional changes in skeletal muscle in young men

(2010) A. C. Alibegovic et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The microRNA miR-696 regulates PGC-1α in mouse skeletal muscle in response to physical activity

(2010) Wataru Aoi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Conserved DNA methylation inGadd45a-/-mice

(2010) Nora Engel et al.   Epigenetics

Exercise impacts brain-derived neurotrophic factor plasticity by engaging mechanisms of epigenetic regulation

(2010) F. Gomez-Pinilla et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Environmental epigenetics

(2010) V Bollati et al.   HEREDITY

Exercise Effects on Methylation ofASCGene

(2010) K. Nakajima et al.   INTERNATIONAL JOURNAL OF SPORTS MEDICINE

A transcriptional map of the impact of endurance exercise training on skeletal muscle phenotype

(2010) Pernille Keller et al.   JOURNAL OF APPLIED PHYSIOLOGY

High responders to resistance exercise training demonstrate differential regulation of skeletal muscle microRNA expression

(2010) Peter K. Davidsen et al.   JOURNAL OF APPLIED PHYSIOLOGY

Genomic predictors of the maximal O2 uptake response to standardized exercise training programs

(2010) Claude Bouchard et al.   JOURNAL OF APPLIED PHYSIOLOGY

Muscle specific microRNAs are regulated by endurance exercise in human skeletal muscle

(2010) Søren Nielsen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Distinct Alterations in Chromatin Organization of the Two IGF-I Promoters Precede Growth Hormone-Induced Activation of IGF-I Gene Transcription

(2010) Dennis J. Chia et al.   MOLECULAR ENDOCRINOLOGY

DNMT1 maintains progenitor function in self-renewing somatic tissue

(2010) George L. Sen et al.   NATURE

Establishing, maintaining and modifying DNA methylation patterns in plants and animals

(2010) Julie A. Law et al.   NATURE REVIEWS GENETICS

A Gene for Speed: The Emerging Role of α-Actinin-3 in Muscle Metabolism

(2010) Yemima Berman et al.   PHYSIOLOGY

Gemcitabine Functions Epigenetically by Inhibiting Repair Mediated DNA Demethylation

(2010) Andrea Schäfer et al.   PLoS One

Molecular Signals of Epigenetic States

(2010) Roberto Bonasio et al.   SCIENCE

Epigenetics in cancer

(2009) S. Sharma et al.   CARCINOGENESIS

Constructing genomic maps of positive selection in humans: Where do we go from here?

(2009) J. M. Akey   GENOME RESEARCH

ACTN3R577X Polymorphism and Israeli Top-level Athletes

(2009) N. Eynon et al.   INTERNATIONAL JOURNAL OF SPORTS MEDICINE

Exercise-induced histone modifications in human skeletal muscle

(2009) Sean L. McGee et al.   JOURNAL OF PHYSIOLOGY-LONDON

Exercise Improves Cognitive Responses to Psychological Stress through Enhancement of Epigenetic Mechanisms and Gene Expression in the Dentate Gyrus

(2009) Andrew Collins et al.   PLoS One

Neuronal Activity-Induced Gadd45b Promotes Epigenetic DNA Demethylation and Adult Neurogenesis

(2009) D. K. Ma et al.   SCIENCE

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

A Genome-Wide Association Study of Hypertension and Blood Pressure in African Americans

(2009) Adebowale Adeyemo et al.   PLoS Genetics

CaMK activation during exercise is required for histone hyperacetylation and MEF2A binding at the MEF2 site on the Glut4 gene

(2008) James A. H. Smith et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Pyruvate dehydrogenase kinase-4 deficiency lowers blood glucose and improves glucose tolerance in diet-induced obese mice

(2008) Nam Ho Jeoung et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Epigenetics in hyperhomocysteinemic states. A special focus on uremia

(2008) Diego Ingrosso et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

DNA Demethylation in Zebrafish Involves the Coupling of a Deaminase, a Glycosylase, and Gadd45

(2008) Kunal Rai et al.   CELL

Methylation of the Calcium Channel-Related Gene, CACNA2D3, Is Frequent and a Poor Prognostic Factor in Gastric Cancer

(2008) Aira Wanajo et al.   GASTROENTEROLOGY

DNA methylation status is inversely correlated with green tea intake and physical activity in gastric cancer patients

(2008) Yasuhito Yuasa et al.   INTERNATIONAL JOURNAL OF CANCER

Randomized Clinical Trials and Observational Studies

(2008) Edward L. Hannan   JACC-Cardiovascular Interventions

Cyclical DNA methylation of a transcriptionally active promoter

(2008) Raphaël Métivier et al.   NATURE

Transient cyclical methylation of promoter DNA

(2008) Sara Kangaspeska et al.   NATURE

Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA

(2008) Wenqiang Yu et al.   NATURE

GADD45A Does Not Promote DNA Demethylation

(2008) Seung-Gi Jin et al.   PLoS Genetics