A new flow cell and chemometric protocol for implementing in‐line Raman spectroscopy in chromatography

Advances in downstream processing of biologics – Spectroscopy: An emerging process analytical technology

(2017) Matthias Rüdt et al.   JOURNAL OF CHROMATOGRAPHY A

Process performance and product quality in an integrated continuous antibody production process

(2016) Daniel J. Karst et al.   BIOTECHNOLOGY AND BIOENGINEERING

Real-time monitoring and control of the load phase of a protein A capture step

(2016) Matthias Rüdt et al.   BIOTECHNOLOGY AND BIOENGINEERING

Robust factor selection in early cell culture process development for the production of a biosimilar monoclonal antibody

(2016) Michael Sokolov et al.   BIOTECHNOLOGY PROGRESS

Using Raman spectroscopy to characterize biological materials

(2016) Holly J Butler et al.   Nature Protocols

On-line monitoring of downstream bioprocesses

(2016) Patricia Roch et al.   Current Opinion in Chemical Engineering

Quick generation of Raman spectroscopy based in-process glucose control to influence biopharmaceutical protein product quality during mammalian cell culture

(2015) Brandon N. Berry et al.   BIOTECHNOLOGY PROGRESS

Assessment of Recent Process Analytical Technology (PAT) Trends: A Multiauthor Review

(2015) Levente L. Simon et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

At-line mid infrared spectroscopy for monitoring downstream processing unit operations

(2015) Florian Capito et al.   PROCESS BIOCHEMISTRY

Application of process analytical technology for downstream purification of biotherapeutics

(2014) Anurag S. Rathore et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Comparison of PAT based approaches for making real-time pooling decisions for process chromatography - use of feed forward control

(2014) Rakesh Mendhe et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Mid-infrared spectroscopy-based antibody aggregate quantification in cell culture fluids

(2013) Florian Capito et al.   Biotechnology Journal

Online control of the twin-column countercurrent solvent gradient process for biochromatography

(2013) M. Krättli et al.   JOURNAL OF CHROMATOGRAPHY A

Host cell protein quantification by fourier transform mid infrared spectroscopy (FT-MIR)

(2012) Florian Capito et al.   BIOTECHNOLOGY AND BIOENGINEERING

In situ Raman spectroscopy for simultaneous monitoring of multiple process parameters in mammalian cell culture bioreactors

(2012) Jessica Whelan et al.   BIOTECHNOLOGY PROGRESS

Process analytical technology (PAT) for biopharmaceutical products

(2010) A. S. Rathore et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Variable selection in regression-a tutorial

(2010) C. M. Andersen et al.   JOURNAL OF CHEMOMETRICS