Application of process analytical technology for downstream purification of biotherapeutics

Avoiding antibody aggregation during processing: Establishing hold times

(2014) Varsha Joshi et al.   Biotechnology Journal

Mechanistic modeling of viral filtration

(2014) Anurag S. Rathore et al.   JOURNAL OF MEMBRANE SCIENCE

Rapid process development of chromatographic process using direct analysis in real time mass spectrometry as a process analytical technology tool

(2014) Binjun Yan et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Getting ready for PAT: Scale up and inline monitoring of protein refolding of Npro fusion proteins

(2014) Cornelia Walther et al.   PROCESS BIOCHEMISTRY

Quantification of protein mixture in chromatographic separation using multi-wavelength UV spectra

(2013) Mark-Henry Kamga et al.   BIOTECHNOLOGY PROGRESS

Refolding of biotech therapeutic proteins expressed in bacteria: review

(2013) Anurag S. Rathore et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Utilizing Dynamic Light Scattering as a Process Analytical Technology for Protein Folding and Aggregation Monitoring in Vaccine Manufacturing

(2013) Zhou Yu et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Chemometrics applications in biotechnology processes: Predicting column integrity and impurity clearance during reuse of chromatography resin

(2012) Anurag S. Rathore et al.   BIOTECHNOLOGY PROGRESS

Risk–benefit evaluation of on-line high-performance liquid chromatography analysis for pooling decisions in large-scale chromatography

(2012) Oliver Kaltenbrunner et al.   JOURNAL OF CHROMATOGRAPHY A

Techno-economic evaluation of an inclusion body solubilization and recombinant protein refolding process

(2011) Esteban J. Freydell et al.   BIOTECHNOLOGY PROGRESS

Integration of Ultrafiltration Unit Operations in Biotechnology Process Design

(2011) F. Grote et al.   CHEMICAL ENGINEERING & TECHNOLOGY

RECENT DEVELOPMENTS IN MEMBRANE-BASED SEPARATIONS IN BIOTECHNOLOGY PROCESSES: REVIEW

(2011) A. S. Rathore et al.   PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY

Process analytical technology (PAT) for biopharmaceutical products

(2010) A. S. Rathore et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Improved process analytical technology for protein a chromatography using predictive principal component analysis tools

(2010) Ying Hou et al.   BIOTECHNOLOGY AND BIOENGINEERING

Applied advanced process analytics in biopharmaceutical manufacturing: Challenges and prospects in real-time monitoring and control

(2010) Cenk Ündey et al.   JOURNAL OF PROCESS CONTROL

Biomanufacturing process analytical technology (PAT) application for downstream processing: Using dissolved oxygen as an indicator of product quality for a protein refolding reaction

(2009) Shelly A. Pizarro et al.   BIOTECHNOLOGY AND BIOENGINEERING

Process analytical technology (PAT) for biopharmaceutical products: Part II. Concepts and applications

(2009) E.K. Read et al.   BIOTECHNOLOGY AND BIOENGINEERING

Process analytical technology (PAT) for biopharmaceutical products: Part I. concepts and applications

(2009) E.K. Read et al.   BIOTECHNOLOGY AND BIOENGINEERING

Case study and application of process analytical technology (PAT) towards bioprocessing: Use of tryptophan fluorescence as at-line tool for making pooling decisions for process chromatography

(2009) Anurag S. Rathore et al.   BIOTECHNOLOGY PROGRESS

Use of PAT principles for the open-loop control of laboratory and pilot-scale chromatography columns

(2009) S. Chhatre et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Characterization of High-Molecular-Weight Nonnative Aggregates and Aggregation Kinetics by Size Exclusion Chromatography With Inline Multi-Angle Laser Light Scattering

(2009) Yi Li et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Microfluidic Mixers for the Investigation of Rapid Protein Folding Kinetics Using Synchrotron Radiation Circular Dichroism Spectroscopy

(2008) Avinash S. Kane et al.   ANALYTICAL CHEMISTRY

Case study and application of process analytical technology (PAT) towards bioprocessing: Use of on-line high-performance liquid chromatography (HPLC) for making real-time pooling decisions for process chromatography

(2007) Anurag S. Rathore et al.   BIOTECHNOLOGY AND BIOENGINEERING