STRIPAK, a highly conserved signaling complex, controls multiple eukaryotic cellular and developmental processes and is linked with human diseases

Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling

(2019) Yang Tang et al.   Cell Discovery

Assembly of a heptameric STRIPAK complex is required for coordination of light-dependent multicellular fungal development with secondary metabolism in Aspergillus nidulans

(2019) Nadia Elramli et al.   PLoS Genetics

A Hippo Pathway Related GCK Controls Both Sexual and Vegetative Developmental Processes in the FungusSordaria macrospora

(2018) Daria Radchenko et al.   GENETICS

Striatin-1 is a B subunit of protein phosphatase PP2A that regulates dendritic arborization and spine development in striatal neurons

(2018) Daniel Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fungal Morphogenesis, from the Polarized Growth of Hyphae to Complex Reproduction and Infection Structures

(2018) Meritxell Riquelme et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The PP2A-like Protein Phosphatase Ppg1 and the Far Complex Cooperatively Counteract CK2-Mediated Phosphorylation of Atg32 to Inhibit Mitophagy

(2018) Kentaro Furukawa et al.   Cell Reports

A Hippo Pathway Related GCK Controls Both Sexual and Vegetative Developmental Processes in the FungusSordaria macrospora

(2018) Daria Radchenko et al.   GENETICS

A novel STRIPAK complex component mediates hyphal fusion and fruiting-body development in filamentous fungi

(2018) Eva Johanna Reschka et al.   MOLECULAR MICROBIOLOGY

17β-estradiol upregulates striatin protein levels via Akt pathway in human umbilical vein endothelial cells

(2018) Shuhui Zheng et al.   PLoS One

Distinct B subunits of PP2A regulate the NF-κB signalling pathway through dephosphorylation of IKKβ, IκBα and RelA

(2017) Yoshihiro Tsuchiya et al.   FEBS LETTERS

A STRIPAK complex mediates axonal transport of autophagosomes and dense core vesicles through PP2A regulation

(2017) Amanda L. Neisch et al.   JOURNAL OF CELL BIOLOGY

Homeostatic Control of Hpo/MST Kinase Activity through Autophosphorylation-Dependent Recruitment of the STRIPAK PP2A Phosphatase Complex

(2017) Yonggang Zheng et al.   Cell Reports

SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK

(2017) Sung Jun Bae et al.   eLife

STRIP2 Is Indispensable for the Onset of Embryonic Stem Cell Differentiation

(2017) Davood Sabour et al.   Molecular Therapy-Methods & Clinical Development

Glucocorticoid Receptor-mediated transactivation is hampered by Striatin-3, a novel interaction partner of the receptor

(2017) Ioanna Petta et al.   Scientific Reports

A role for post-transcriptional control of endoplasmic reticulum dynamics and function inC. elegansgermline stem cell maintenance

(2016) Richa Maheshwari et al.   DEVELOPMENT

Overexpression of protein kinase STK25 in mice exacerbates ectopic lipid accumulation, mitochondrial dysfunction and insulin resistance in skeletal muscle

(2016) Urszula Chursa et al.   DIABETOLOGIA

The composition and function of the striatin-interacting phosphatases and kinases (STRIPAK) complex in fungi

(2016) Ulrich Kück et al.   FUNGAL GENETICS AND BIOLOGY

Mechanisms of Hippo pathway regulation

(2016) Zhipeng Meng et al.   GENES & DEVELOPMENT

AnEpichloë festucaehomologue of MOB3, a component of the STRIPAK complex, is required for the establishment of a mutualistic symbiotic interaction withLolium perenne

(2016) Kimberly A. Green et al.   MOLECULAR PLANT PATHOLOGY

STRIPAK complexes in cell signaling and cancer

(2016) Z Shi et al.   ONCOGENE

The Strip-Hippo Pathway Regulates Synaptic Terminal Formation by Modulating Actin Organization at the Drosophila Neuromuscular Synapses

(2016) Chisako Sakuma et al.   Cell Reports

The MST/Hippo Pathway and Cell Death: A Non-Canonical Affair

(2016) Emma Fallahi et al.   Genes

Protein kinase STK25 controls lipid partitioning in hepatocytes and correlates with liver fat content in humans

(2015) Manoj Amrutkar et al.   DIABETOLOGIA

MST kinases in development and disease

(2015) Barry J. Thompson et al.   JOURNAL OF CELL BIOLOGY

Pombe's thirteen - control of fission yeast cell division by the septation initiation network

(2015) V. Simanis   JOURNAL OF CELL SCIENCE

Mammalian Ste20-Like Kinase 4 Promotes Pituitary Cell Proliferation and Survival Under Hypoxia

(2015) Weipeng Xiong et al.   MOLECULAR ENDOCRINOLOGY

The kinases NDR1/2 act downstream of the Hippo homolog MST1 to mediate both egress of thymocytes from the thymus and lymphocyte motility

(2015) Fengyuan Tang et al.   Science Signaling

MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway

(2015) Zhipeng Meng et al.   Nature Communications

Daytime CLOCK Dephosphorylation Is Controlled by STRIPAK Complexes in Drosophila

(2015) Simonetta Andreazza et al.   Cell Reports

The kinases NDR1/2 act downstream of the Hippo homolog MST1 to mediate both egress of thymocytes from the thymus and lymphocyte motility

(2015) Fengyuan Tang et al.   Science Signaling

Silencing of STRN4 suppresses the malignant characteristics of cancer cells

(2014) Meihong Wong et al.   CANCER SCIENCE

A Fungal Sarcolemmal Membrane-Associated Protein (SLMAP) Homolog Plays a Fundamental Role in Development and Localizes to the Nuclear Envelope, Endoplasmic Reticulum, and Mitochondria

(2014) Steffen Nordzieke et al.   EUKARYOTIC CELL

Insight into Tor2, a budding yeast microdomain protein

(2014) Katelyn Bartlett et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Striatins Contain a Noncanonical Coiled Coil That Binds Protein Phosphatase 2A A Subunit to Form a 2:2 Heterotetrameric Core of Striatin-interacting Phosphatase and Kinase (STRIPAK) Complex

(2014) Cuicui Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MST3 Kinase Phosphorylates TAO1/2 to Enable Myosin Va Function in Promoting Spine Synapse Development

(2014) Sila K. Ultanir et al.   NEURON

Proper Actin Ring Formation and Septum Constriction Requires Coordinated Regulation of SIN and MOR Pathways through the Germinal Centre Kinase MST-1

(2014) Yvonne Heilig et al.   PLoS Genetics

STRIPAK complexes: Structure, biological function, and involvement in human diseases

(2013) Juyeon Hwang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Tiered Assembly of the Yeast Far3-7-8-9-10-11 Complex at the Endoplasmic Reticulum

(2013) Tammy Pracheil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Association of Dilated Cardiomyopathy with the Striatin Mutation Genotype in Boxer Dogs

(2013) K.M. Meurs et al.   JOURNAL OF VETERINARY INTERNAL MEDICINE

HAM-2 and HAM-3 are central for the assembly of theNeurospora STRIPAK complex at the nuclear envelope and regulate nuclear accumulation of the MAP kinase MAK-1 in a MAK-2-dependent manner

(2013) Anne Dettmann et al.   MOLECULAR MICROBIOLOGY

Phospho-Regulation of the Neurospora crassa Septation Initiation Network

(2013) Yvonne Heilig et al.   PLoS One

Protein Interaction Network of the Mammalian Hippo Pathway Reveals Mechanisms of Kinase-Phosphatase Interactions

(2013) A. L. Couzens et al.   Science Signaling

Septum development in filamentous ascomycetes

(2013) Rosa R. Mouriño-Pérez   Fungal Biology Reviews

Functional Repurposing Revealed by Comparing S. pombe and S. cerevisiae Genetic Interactions

(2012) Adam Frost et al.   CELL

A Novel Disease Gene for Brugada Syndrome

(2012) Taisuke Ishikawa et al.   Circulation-Arrhythmia and Electrophysiology

TORC2 Signaling Is Antagonized by Protein Phosphatase 2A and the Far Complex in Saccharomyces cerevisiae

(2012) T. Pracheil et al.   GENETICS

CTTNBP2, but not CTTNBP2NL, regulates dendritic spinogenesis and synaptic distribution of the striatin–PP2A complex

(2012) Yi-Kai Chen et al.   MOLECULAR BIOLOGY OF THE CELL

A homologue of the human STRIPAK complex controls sexual development in fungi

(2012) Sandra Bloemendal et al.   MOLECULAR MICROBIOLOGY

Comparative Live-Cell Imaging Analyses of SPA-2, BUD-6 and BNI-1 in Neurospora crassa Reveal Novel Features of the Filamentous Fungal Polarisome

(2012) Alexander Lichius et al.   PLoS One

Protein phosphatase 2a (PP2A) binds within the oligomerization domain of striatin and regulates the phosphorylation and activation of the mammalian Ste20-Like kinase Mst3

(2011) Johnthan Gordon et al.   BMC BIOCHEMISTRY

Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration

(2011) Siau Bai et al.   BMC BIOLOGY

SIN-Inhibitory Phosphatase Complex Promotes Cdc11p Dephosphorylation and Propagates SIN Asymmetry in Fission Yeast

(2011) N. Sadananda Singh et al.   CURRENT BIOLOGY

The phocein homologue SmMOB3 is essential for vegetative cell fusion and sexual development in the filamentous ascomycete Sordaria macrospora

(2011) Yasmine Bernhards et al.   CURRENT GENETICS

Tao-1 Phosphorylates Hippo/MST Kinases to Regulate the Hippo-Salvador-Warts Tumor Suppressor Pathway

(2011) Julian C. Boggiano et al.   DEVELOPMENTAL CELL

Identification and Characterization of Genes Required for Cell-to-Cell Fusion in Neurospora crassa

(2011) Ci Fu et al.   EUKARYOTIC CELL

Functional Characterization and Cellular Dynamics of the CDC-42 – RAC – CDC-24 Module in Neurospora crassa

(2011) Cynthia L. Araujo-Palomares et al.   PLoS One

Ste20-related kinases: effectors of signaling and morphogenesis in fungi

(2011) Kylie J. Boyce et al.   TRENDS IN MICROBIOLOGY

The Hippo Signaling Pathway in Development and Cancer

(2010) Duojia Pan   DEVELOPMENTAL CELL

A Mutant Defective in Sexual Development Produces Aseptate Ascogonia

(2010) Sandra Bloemendal et al.   EUKARYOTIC CELL

Genes encoding a striatin-like protein (ham-3) and a forkhead associated protein (ham-4) are required for hyphal fusion in Neurospora crassa

(2010) Anna R. Simonin et al.   FUNGAL GENETICS AND BIOLOGY

Visualization of F-actin localization and dynamics with live cell markers in Neurospora crassa

(2010) Diego L. Delgado-Álvarez et al.   FUNGAL GENETICS AND BIOLOGY

Aspergillus nidulans striatin (StrA) mediates sexual development and localizes to the endoplasmic reticulum

(2010) Chih-Li Wang et al.   FUNGAL GENETICS AND BIOLOGY

Combined Functional Genomic and Proteomic Approaches Identify a PP2A Complex as a Negative Regulator of Hippo Signaling

(2010) Paulo S. Ribeiro et al.   MOLECULAR CELL

Hydrophobic profiles of the tail anchors in SLMAP dictate subcellular targeting

(2009) Joseph T Byers et al.   BMC CELL BIOLOGY

Actin Dynamics at the Leading Edge: From Simple Machinery to Complex Networks

(2009) Robert H. Insall et al.   DEVELOPMENTAL CELL

The mammalian family of sterile 20p-like protein kinases

(2009) Eric Delpire   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

A PP2A Phosphatase High Density Interaction Network Identifies a Novel Striatin-interacting Phosphatase and Kinase Complex Linked to the Cerebral Cavernous Malformation 3 (CCM3) Protein

(2008) Marilyn Goudreault et al.   MOLECULAR & CELLULAR PROTEOMICS

Branching of fungal hyphae: regulation, mechanisms and comparison with other branching systems

(2008) Steven D. Harris   MYCOLOGIA