The kinases NDR1/2 act downstream of the Hippo homolog MST1 to mediate both egress of thymocytes from the thymus and lymphocyte motility

NDR Functions as a Physiological YAP1 Kinase in the Intestinal Epithelium

(2015) Lei Zhang et al.   CURRENT BIOLOGY

Thymic Emigration: When and How T Cells Leave Home

(2014) M. A. Weinreich et al.   JOURNAL OF IMMUNOLOGY

Rab13 acts downstream of the kinase Mst1 to deliver the integrin LFA-1 to the cell surface for lymphocyte trafficking

(2014) A. Nishikimi et al.   Science Signaling

Dynamic phosphorylation of HP1α regulates mitotic progression in human cells

(2014) Arindam Chakraborty et al.   Nature Communications

The Hippo pathway: regulators and regulations

(2013) F.-X. Yu et al.   GENES & DEVELOPMENT

DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses

(2012) Y. Harada et al.   BLOOD

The phenotype of human STK4 deficiency

(2012) H. Abdollahpour et al.   BLOOD

Abstract 5386: Immunotherapy of bladder cancer using bacillus calmette guérin (BCG): Generation of cytotoxic T-cells is BCG strain dependent

(2012) Joël R. Gsponer et al.   CANCER RESEARCH

The Mst1 and Mst2 kinases control activation of rho family GTPases and thymic egress of mature thymocytes

(2012) Fan Mou et al.   JOURNAL OF EXPERIMENTAL MEDICINE

STK38 is a critical upstream regulator of MYC’s oncogenic activity in human B-cell lymphoma

(2012) B C Bisikirska et al.   ONCOGENE

Mst1 regulates integrin-dependent thymocyte trafficking and antigen recognition in the thymus

(2012) Yoshihiro Ueda et al.   Nature Communications

MST1 mutations in autosomal recessive primary immunodeficiency characterized by defective naive T-cell survival

(2011) N. T. Nehme et al.   BLOOD

Downstream of human NDR kinases: Impacting on c-myc and p21 protein stability to control cell cycle progression

(2011) Hauke Cornils et al.   CELL CYCLE

Human NDR Kinases Control G1/S Cell Cycle Transition by Directly Regulating p21 Stability

(2011) H. Cornils et al.   MOLECULAR AND CELLULAR BIOLOGY

The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal

(2011) Bin Zhao et al.   NATURE CELL BIOLOGY

Comprehensive analysis of lymph node stroma-expressed Ig superfamily members reveals redundant and nonredundant roles for ICAM-1, ICAM-2, and VCAM-1 in lymphocyte homing

(2010) R. T. Boscacci et al.   BLOOD

MST1 Limits the Kinase Activity of Aurora B to Promote Stable Kinetochore-Microtubule Attachment

(2010) Hyun Jung Oh et al.   CURRENT BIOLOGY

The Hippo Signaling Pathway in Development and Cancer

(2010) Duojia Pan   DEVELOPMENTAL CELL

Neural Crest-Derived Pericytes Promote Egress of Mature Thymocytes at the Corticomedullary Junction

(2010) M. A. Zachariah et al.   SCIENCE

Ablation of the Kinase NDR1 Predisposes Mice to the Development of T Cell Lymphoma

(2010) H. Cornils et al.   Science Signaling

MST2- and Furry-Mediated Activation of NDR1 Kinase Is Critical for Precise Alignment of Mitotic Chromosomes

(2009) Shuhei Chiba et al.   CURRENT BIOLOGY

The MST1 and hMOB1 Tumor Suppressors Control Human Centrosome Duplication by Regulating NDR Kinase Phosphorylation

(2009) Alexander Hergovich et al.   CURRENT BIOLOGY

Mst1 controls lymphocyte trafficking and interstitial motility within lymph nodes

(2009) Koko Katagiri et al.   EMBO JOURNAL

Large deletions and point mutations involving the dedicator of cytokinesis 8 (DOCK8) in the autosomal-recessive form of hyper-IgE syndrome

(2009) Karin R. Engelhardt et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A Cell-Intrinsic Role for Mst1 in Regulating Thymocyte Egress

(2009) Y. Dong et al.   JOURNAL OF IMMUNOLOGY

Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production

(2009) Katrina L Randall et al.   NATURE IMMUNOLOGY

Combined Immunodeficiency Associated withDOCK8Mutations

(2009) Qian Zhang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mst1-FoxO Signaling Protects Naïve T Lymphocytes from Cellular Oxidative Stress in Mice

(2009) Juhyun Choi et al.   PLoS One

MOBKL1A/MOBKL1B Phosphorylation by MST1 and MST2 Inhibits Cell Proliferation

(2008) Maria Praskova et al.   CURRENT BIOLOGY

NDR Kinase Is Activated by RASSF1A/MST1 in Response to Fas Receptor Stimulation and Promotes Apoptosis

(2008) Anton Vichalkovski et al.   CURRENT BIOLOGY

Homeostasis of Naive and Memory T Cells

(2008) Charles D. Surh et al.   IMMUNITY

Orchestrating the orchestrators: chemokines in control of T cell traffic

(2008) Shannon K Bromley et al.   NATURE IMMUNOLOGY

How chemokines invite leukocytes to dance

(2008) Marcus Thelen et al.   NATURE IMMUNOLOGY

The Nore1B/Mst1 complex restrains antigen receptor-induced proliferation of naive T cells

(2008) D. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA