An atypical LIR motif within UBA5 (ubiquitin like modifier activating enzyme 5) interacts with GABARAP proteins and mediates membrane localization of UBA5

Biallelic UFM1 and UFC1 mutations expand the essential role of ufmylation in brain development

(2018) Michael S Nahorski et al.   BRAIN

Mechanism of Stx17 recruitment to autophagosomes via IRGM and mammalian Atg8 proteins

(2018) Suresh Kumar et al.   JOURNAL OF CELL BIOLOGY

Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins

(2018) Jianchao Li et al.   Nature Chemical Biology

A helical LC3-interacting region mediates the interaction between the retroviral restriction factor Trim5α and mammalian autophagy-related ATG8 proteins

(2018) Jeremy R. Keown et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A critical role of DDRGK1 in endoplasmic reticulum homoeostasis via regulation of IRE1α stability

(2017) Jiang Liu et al.   Nature Communications

The crystal structure of mouse LC3B in complex with the FYCO1 LIR reveals the importance of the flanking region of the LIR motif

(2017) Shunya Sakurai et al.   Acta Crystallographica Section F-Structural Biology Communications

The Atg8 Family of Proteins—Modulating Shape and Functionality of Autophagic Membranes

(2017) Iman Abdollahzadeh et al.   Frontiers in Genetics

Plasmodium UIS3 sequesters host LC3 to avoid elimination by autophagy in hepatocytes

(2017) Eliana Real et al.   Nature Microbiology

Biallelic Variants in UBA5 Link Dysfunctional UFM1 Ubiquitin-like Modifier Pathway to Severe Infantile-Onset Encephalopathy

(2016) Mikko Muona et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Biallelic Variants in UBA5 Reveal that Disruption of the UFM1 Cascade Can Result in Early-Onset Encephalopathy

(2016) Estelle Colin et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Structural basis of FYCO1 and MAP1LC3A interaction reveals a novel binding mode for Atg8-family proteins

(2016) Xiaofang Cheng et al.   Autophagy

iLIR database: A web resource for LIR motif-containing proteins in eukaryotes

(2016) Anne-Claire Jacomin et al.   Autophagy

Fluorescence‐based ATG8 sensors monitor localization and function of LC3/GABARAP proteins

(2016) Alexandra Stolz et al.   EMBO JOURNAL

A novel approach to assess the ubiquitin-fold modifier 1-system in cells

(2016) Ryosuke Ishimura et al.   FEBS LETTERS

Structural and Functional Analysis of a Novel Interaction Motif within UFM1-activating Enzyme 5 (UBA5) Required for Binding to Ubiquitin-like Proteins and Ufmylation

(2016) Sabrina Habisov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Atg8 family LC3/GABARAP proteins are crucial for autophagosome–lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation

(2016) Thanh Ngoc Nguyen et al.   JOURNAL OF CELL BIOLOGY

UBA5 Mutations Cause a New Form of Autosomal Recessive Cerebellar Ataxia

(2016) Ranhui Duan et al.   PLoS One

FYCO1 Contains a C-terminally Extended, LC3A/B-preferring LC3-interacting Region (LIR) Motif Required for Efficient Maturation of Autophagosomes during Basal Autophagy

(2015) Hallvard L. Olsvik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Combined automated NOE assignment and structure calculation with CYANA

(2015) Peter Güntert et al.   JOURNAL OF BIOMOLECULAR NMR

TECPR2 Cooperates with LC3C to Regulate COPII-Dependent ER Export

(2015) Daniela Stadel et al.   MOLECULAR CELL

CUL3-KBTBD6/KBTBD7 Ubiquitin Ligase Cooperates with GABARAP Proteins to Spatially Restrict TIAM1-RAC1 Signaling

(2015) Heide Marika Genau et al.   MOLECULAR CELL

Structural Basis of the Differential Function of the Two C. elegans Atg8 Homologs, LGG-1 and LGG-2, in Autophagy

(2015) Fan Wu et al.   MOLECULAR CELL

Activation of ULK Kinase and Autophagy by GABARAP Trafficking from the Centrosome Is Regulated by WAC and GM130

(2015) Justin Joachim et al.   MOLECULAR CELL

Autophagic Degradation of the 26S Proteasome Is Mediated by the Dual ATG8/Ubiquitin Receptor RPN10 in Arabidopsis

(2015) Richard S. Marshall et al.   MOLECULAR CELL

Phosphorylation of LC3 by the Hippo Kinases STK3/STK4 Is Essential for Autophagy

(2015) Deepti S. Wilkinson et al.   MOLECULAR CELL

UFBP1, a Key Component of the Ufm1 Conjugation System, Is Essential for Ufmylation-Mediated Regulation of Erythroid Development

(2015) Yafei Cai et al.   PLoS Genetics

The Autophagy Receptor TAX1BP1 and the Molecular Motor Myosin VI Are Required for Clearance of Salmonella Typhimurium by Autophagy

(2015) David A. Tumbarello et al.   PLoS Pathogens

Structural determinants in GABARAP required for the selective binding and recruitment of ALFY to LC3B-positive structures

(2014) A. H. Lystad et al.   EMBO REPORTS

Interactions between Autophagy Receptors and Ubiquitin-like Proteins Form the Molecular Basis for Selective Autophagy

(2014) Vladimir Rogov et al.   MOLECULAR CELL

Modification of ASC1 by UFM1 Is Crucial for ERα Transactivation and Breast Cancer Development

(2014) Hee Min Yoo et al.   MOLECULAR CELL

An ER Complex of ODR-4 and ODR-8/Ufm1 Specific Protease 2 Promotes GPCR Maturation by a Ufm1-Independent Mechanism

(2014) Changchun Chen et al.   PLoS Genetics

The Ufm1 Cascade

(2014) Jens Daniel et al.   Cells

BEST-TROSY experiments for time-efficient sequential resonance assignment of large disordered proteins

(2013) Zsofia Solyom et al.   JOURNAL OF BIOMOLECULAR NMR

The scaffold protein EPG-7 links cargo–receptor complexes with the autophagic assembly machinery

(2013) Long Lin et al.   JOURNAL OF CELL BIOLOGY

Structural Basis of the Autophagy-Related LC3/Atg13 LIR Complex: Recognition and Interaction Mechanism

(2013) Hironori Suzuki et al.   STRUCTURE

A Universal Expression Tag for Structural and Functional Studies of Proteins

(2012) Vladimir V. Rogov et al.   CHEMBIOCHEM

LC3C, Bound Selectively by a Noncanonical LIR Motif in NDP52, Is Required for Antibacterial Autophagy

(2012) Natalia von Muhlinen et al.   MOLECULAR CELL

Deletion of mitochondrial associated ubiquitin fold modifier protein Ufm1 inLeishmania donovaniresults in loss of β-oxidation of fatty acids and blocks cell division in the amastigote stage

(2012) Sreenivas Gannavaram et al.   MOLECULAR MICROBIOLOGY

Transcriptional Regulation of the Ufm1 Conjugation System in Response to Disturbance of the Endoplasmic Reticulum Homeostasis and Inhibition of Vesicle Trafficking

(2012) Yinghua Zhang et al.   PLoS One

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Structural Basis of Atg8 Activation by a Homodimeric E1, Atg7

(2011) Nobuo N. Noda et al.   MOLECULAR CELL

Ubiquitin Fold Modifier 1 (UFM1) and Its Target UFBP1 Protect Pancreatic Beta Cells from ER Stress-Induced Apoptosis

(2011) Katleen Lemaire et al.   PLoS One

The Ufm1-activating enzyme Uba5 is indispensable for erythroid differentiation in mice

(2011) Kanako Tatsumi et al.   Nature Communications

Atg8: an autophagy-related ubiquitin-like protein family

(2011) Tomer Shpilka et al.   GENOME BIOLOGY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Solution structure of Atg8 reveals conformational polymorphism of the N-terminal domain

(2010) Melanie Schwarten et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis

(2010) Hilla Weidberg et al.   EMBO JOURNAL

Atg8-family interacting motif crucial for selective autophagy

(2010) Nobuo N. Noda et al.   FEBS LETTERS

Crystal Structure of the Human Ubiquitin-activating Enzyme 5 (UBA5) Bound to ATP

(2010) John-Paul Bacik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Network organization of the human autophagy system

(2010) Christian Behrends et al.   NATURE

Selective autophagy: ubiquitin-mediated recognition and beyond

(2010) Claudine Kraft et al.   NATURE CELL BIOLOGY

Eaten alive: a history of macroautophagy

(2010) Zhifen Yang et al.   NATURE CELL BIOLOGY

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

A Novel Type of E3 Ligase for the Ufm1 Conjugation System

(2009) Kanako Tatsumi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Longitudinal-Relaxation-Enhanced NMR Experiments for the Study of Nucleic Acids in Solution

(2009) Jonathan Farjon et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Role for Ubiquitin in Selective Autophagy

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

Structural basis of target recognition by Atg8/LC3 during selective autophagy

(2008) Nobuo N. Noda et al.   GENES TO CELLS

Structural Basis for Sorting Mechanism of p62 in Selective Autophagy

(2008) Yoshinobu Ichimura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ligand Binding Mode of GABAA Receptor-Associated Protein

(2008) Oliver H. Weiergräber et al.   JOURNAL OF MOLECULAR BIOLOGY