Disruption of the Extracellular Matrix Progressively Impairs Central Nervous System Vascular Maturation Downstream of β-Catenin Signaling

A molecular mechanism for Wnt ligand-specific signaling

(2018) Marie Eubelen et al.   SCIENCE

The vascular basement membrane in the healthy and pathological brain

(2017) Maj S Thomsen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Establishment and Dysfunction of the Blood-Brain Barrier

(2015) Zhen Zhao et al.   CELL

Adamtsl2 deletion results in bronchial fibrillin microfibril accumulation and bronchial epithelial dysplasia - a novel mouse model providing insights into geleophysic dysplasia

(2015) D. Hubmacher et al.   Disease Models & Mechanisms

Tip cell-specific requirement for an atypical Gpr124- and Reck-dependent Wnt/β-catenin pathway during brain angiogenesis

(2015) Benoit Vanhollebeke et al.   eLife

Novel insights into the development and maintenance of the blood–brain barrier

(2014) Britta Engelhardt et al.   CELL AND TISSUE RESEARCH

Excessive vascular sprouting underlies cerebral hemorrhage in mice lacking  V 8-TGF  signaling in the brain

(2014) T. D. Arnold et al.   DEVELOPMENT

Canonical WNT signaling components in vascular development and barrier formation

(2014) Yulian Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

The Extracellular Matrix Protein Laminin  2 Regulates the Maturation and Function of the Blood-Brain Barrier

(2014) M. J. Menezes et al.   JOURNAL OF NEUROSCIENCE

Mfsd2a is critical for the formation and function of the blood–brain barrier

(2014) Ayal Ben-Zvi et al.   NATURE

New insights into the regulation of Axin function in canonical Wnt signaling pathway

(2014) Xiaomin Song et al.   Protein & Cell

Evaluation of TRAP-sequencing technology with a versatile conditional mouse model

(2013) Mike Hupe et al.   NUCLEIC ACIDS RESEARCH

Radial Glial Neural Progenitors Regulate Nascent Brain Vascular Network Stabilization Via Inhibition of Wnt Signaling

(2013) Shang Ma et al.   PLOS BIOLOGY

Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions

(2012) F. Itoh et al.   BLOOD

Norrin/Frizzled4 Signaling in Retinal Vascular Development and Blood Brain Barrier Plasticity

(2012) Yanshu Wang et al.   CELL

In vivo Wnt signaling tracing through a transgenic biosensor fish reveals novel activity domains

(2012) Enrico Moro et al.   DEVELOPMENTAL BIOLOGY

Death Receptors DR6 and TROY Regulate Brain Vascular Development

(2012) Stephen J. Tam et al.   DEVELOPMENTAL CELL

Defective Retinal Vascular Endothelial Cell Development As a Consequence of Impaired Integrin  V 8-Mediated Activation of Transforming Growth Factor- 

(2012) T. D. Arnold et al.   JOURNAL OF NEUROSCIENCE

Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells

(2012) Daniel Ramsköld et al.   NATURE BIOTECHNOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

A sensitive and bright single-cell resolution live imaging reporter of Wnt/ß-catenin signaling in the mouse

(2011) Anna Ferrer-Vaquer et al.   BMC DEVELOPMENTAL BIOLOGY

Waif1/5T4 Inhibits Wnt/β-Catenin Signaling and Activates Noncanonical Wnt Pathways by Modifying LRP6 Subcellular Localization

(2011) Birgit Kagermeier-Schenk et al.   DEVELOPMENTAL CELL

Extracellular matrix and matrix receptors in blood-brain barrier formation and stroke

(2011) Kim M. Baeten et al.   Developmental Neurobiology

Probing transcription-specific outputs of  -catenin in vivo

(2011) T. Valenta et al.   GENES & DEVELOPMENT

The ADAMTS(L) family and human genetic disorders

(2011) C. Le Goff et al.   HUMAN MOLECULAR GENETICS

TGF-β signaling in endothelial cells, but not neuroepithelial cells, is essential for cerebral vascular development

(2011) Ha-Long Nguyen et al.   LABORATORY INVESTIGATION

Angiogenic sprouting into neural tissue requires Gpr124, an orphan G protein-coupled receptor

(2011) K. D. Anderson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier

(2011) M. Cullen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Involvement of the Reck tumor suppressor protein in maternal and embryonic vascular remodeling in mice

(2010) Ediriweera PS Chandana et al.   BMC DEVELOPMENTAL BIOLOGY

Pericytes regulate the blood–brain barrier

(2010) Annika Armulik et al.   NATURE

Pericytes are required for blood–brain barrier integrity during embryogenesis

(2010) Richard Daneman et al.   NATURE

Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging

(2010) Robert D. Bell et al.   NEURON

The Mouse Blood-Brain Barrier Transcriptome: A New Resource for Understanding the Development and Function of Brain Endothelial Cells

(2010) Richard Daneman et al.   PLoS One

Essential Regulation of CNS Angiogenesis by the Orphan G Protein-Coupled Receptor GPR124

(2010) F. Kuhnert et al.   SCIENCE

DLL1-mediated Notch activation regulates endothelial identity in mouse fetal arteries

(2009) I. Sorensen et al.   BLOOD

RETRACTED: Synapse loss regulated by matrix metalloproteinases in traumatic brain injury is associated with hypoxia inducible factor-1α expression

(2009) Jamie Y. Ding et al.   BRAIN RESEARCH

TSPAN12 Regulates Retinal Vascular Development by Promoting Norrin- but Not Wnt-Induced FZD4/β-Catenin Signaling

(2009) Harald J. Junge et al.   CELL

Norrin, Frizzled-4, and Lrp5 Signaling in Endothelial Cells Controls a Genetic Program for Retinal Vascularization

(2009) Xin Ye et al.   CELL

Wnt/ -catenin signaling is required for CNS, but not non-CNS, angiogenesis

(2009) R. Daneman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Abundance of Ubiquitously Expressed Genes Revealed by Tissue Transcriptome Sequence Data

(2009) Daniel Ramsköld et al.   PLoS Computational Biology

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Foxn4 directly regulates tbx2b expression and atrioventricular canal formation

(2008) N. C. Chi et al.   GENES & DEVELOPMENT

Wnt/β-catenin signaling controls development of the blood–brain barrier

(2008) Stefan Liebner et al.   JOURNAL OF CELL BIOLOGY

ADAMTSL2 mutations in geleophysic dysplasia demonstrate a role for ADAMTS-like proteins in TGF-β bioavailability regulation

(2008) Carine Le Goff et al.   NATURE GENETICS

Canonical Wnt Signaling Regulates Organ-Specific Assembly and Differentiation of CNS Vasculature

(2008) J. M. Stenman et al.   SCIENCE