Canonical WNT signaling components in vascular development and barrier formation

Ultrasound-mediated blood–brain barrier disruption for targeted drug delivery in the central nervous system

(2014) Muna Aryal et al.   ADVANCED DRUG DELIVERY REVIEWS

Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF

(2014) Jurian Schuijers et al.   EMBO JOURNAL

Cellular Resolution Maps of X Chromosome Inactivation: Implications for Neural Development, Function, and Disease

(2014) Hao Wu et al.   NEURON

Structure and function of Norrin in assembly and activation of a Frizzled 4-Lrp5/6 complex

(2013) J. Ke et al.   GENES & DEVELOPMENT

Multi-functional norrin is a ligand for the LGR4 receptor

(2013) C. Deng et al.   JOURNAL OF CELL SCIENCE

Development, maintenance and disruption of the blood-brain barrier

(2013) Birgit Obermeier et al.   NATURE MEDICINE

ZNF408 is mutated in familial exudative vitreoretinopathy and is crucial for the development of zebrafish retinal vasculature

(2013) R. W. J. Collin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sox17 is indispensable for acquisition and maintenance of arterial identity

(2013) Monica Corada et al.   Nature Communications

Frizzled3 controls axonal development in distinct populations of cranial and spinal motor neurons

(2013) Zhong L Hua et al.   eLife

How to draw the line in biomedical research

(2013) Lisa Huang et al.   eLife

Norrin/Frizzled4 Signaling in Retinal Vascular Development and Blood Brain Barrier Plasticity

(2012) Yanshu Wang et al.   CELL

Function of Wnt/ -catenin in counteracting Tcf3 repression through the Tcf3- -catenin interaction

(2012) C.-I. Wu et al.   DEVELOPMENT

The many faces and functions of β-catenin

(2012) Tomas Valenta et al.   EMBO JOURNAL

Biological, Preclinical and Clinical Characteristics of Inhibitors of Vascular Endothelial Growth Factors

(2012) Victor Chong   OPHTHALMOLOGICA

Retinal Expression of Wnt-Pathway Mediated Genes in Low-Density Lipoprotein Receptor-Related Protein 5 (Lrp5) Knockout Mice

(2012) Jing Chen et al.   PLoS One

Structural Basis of Wnt Recognition by Frizzled

(2012) C. Y. Janda et al.   SCIENCE

Secreted and Transmembrane Wnt Inhibitors and Activators

(2012) C.-M. Cruciat et al.   Cold Spring Harbor Perspectives in Biology

Basic and Therapeutic Aspects of Angiogenesis

(2011) Michael Potente et al.   CELL

Frizzled 4 Regulates Arterial Network Organization Through Noncanonical Wnt/Planar Cell Polarity Signaling

(2011) Betty Descamps et al.   CIRCULATION RESEARCH

Principles of planar polarity in animal development

(2011) L. V. Goodrich et al.   DEVELOPMENT

Genetic mosaic analysis reveals a major role for frizzled 4 and frizzled 8 in controlling ureteric growth in the developing kidney

(2011) X. Ye et al.   DEVELOPMENT

Lrp5 and Lrp6 redundantly control skeletal development in the mouse embryo

(2011) Kyu Sang Joeng et al.   DEVELOPMENTAL BIOLOGY

Probing transcription-specific outputs of  -catenin in vivo

(2011) T. Valenta et al.   GENES & DEVELOPMENT

A novel mechanism for the transcriptional regulation of Wnt signaling in development

(2011) T. Vacik et al.   GENES & DEVELOPMENT

Clinical Presentation of Familial Exudative Vitreoretinopathy

(2011) Tushar M. Ranchod et al.   OPHTHALMOLOGY

T-cell factor 4 functions as a tumor suppressor whose disruption modulates colon cell proliferation and tumorigenesis

(2011) M. L. Angus-Hill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sensory circumventricular organs in health and disease

(2010) Sílvia Sisó et al.   ACTA NEUROPATHOLOGICA

Next-Generation Sequencing of a 40 Mb Linkage Interval Reveals TSPAN12 Mutations in Patients with Familial Exudative Vitreoretinopathy

(2010) Konstantinos Nikopoulos et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The role of Frizzled-4 mutations in familial exudative vitreoretinopathy and Coats disease

(2010) J. M. Robitaille et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Expression of the Norrie disease gene (Ndp) in developing and adult mouse eye, ear, and brain

(2010) Xin Ye et al.   GENE EXPRESSION PATTERNS

Overview of the mutation spectrum in familial exudative vitreoretinopathy and Norrie disease with identification of 21 novel variants in FZD4, LRP5, and NDP

(2010) Konstantinos Nikopoulos et al.   HUMAN MUTATION

Identification of β-catenin binding regions in colon cancer cells using ChIP-Seq

(2010) Daniel Bottomly et al.   NUCLEIC ACIDS RESEARCH

The Mouse Blood-Brain Barrier Transcriptome: A New Resource for Understanding the Development and Function of Brain Endothelial Cells

(2010) Richard Daneman et al.   PLoS One

The Norrin/Frizzled4 signaling pathway in retinal vascular development and disease

(2010) Xin Ye et al.   TRENDS IN MOLECULAR MEDICINE

TSPAN12 Regulates Retinal Vascular Development by Promoting Norrin- but Not Wnt-Induced FZD4/β-Catenin Signaling

(2009) Harald J. Junge et al.   CELL

Norrin, Frizzled-4, and Lrp5 Signaling in Endothelial Cells Controls a Genetic Program for Retinal Vascularization

(2009) Xin Ye et al.   CELL

Faithful Expression of Multiple Proteins via 2A-Peptide Self-Processing: A Versatile and Reliable Method for Manipulating Brain Circuits

(2009) W. Tang et al.   JOURNAL OF NEUROSCIENCE

Wnt/ -catenin signaling is required for CNS, but not non-CNS, angiogenesis

(2009) R. Daneman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficient, inducible Cre-recombinase activation in vascular endothelium

(2008) Suzanne Claxton et al.   GENESIS

A model for familial exudative vitreoretinopathy caused by LPR5 mutations

(2008) C.-H. Xia et al.   HUMAN MOLECULAR GENETICS

Wnt/β-catenin signaling controls development of the blood–brain barrier

(2008) Stefan Liebner et al.   JOURNAL OF CELL BIOLOGY

The Optokinetic Reflex as a Tool for Quantitative Analyses of Nervous System Function in Mice: Application to Genetic and Drug-Induced Variation

(2008) Hugh Cahill et al.   PLoS One

Canonical Wnt Signaling Regulates Organ-Specific Assembly and Differentiation of CNS Vasculature

(2008) J. M. Stenman et al.   SCIENCE