α‐Synuclein toxicity in yeast and human cells is caused by cell cycle re‐entry and autophagy degradation of ribonucleotide reductase 1

Essential Function of Mec1, the Budding Yeast ATM/ATR Checkpoint-Response Kinase, in Protein Homeostasis

(2018) Isaac Corcoles-Saez et al.   DEVELOPMENTAL CELL

Sodium butyrate rescues dopaminergic cells from alpha-synuclein-induced transcriptional deregulation and DNA damage

(2017) Isabel Paiva et al.   HUMAN MOLECULAR GENETICS

Caloric restriction alleviates alpha-synuclein toxicity in aged yeast cells by controlling the opposite roles of Tor1 and Sir2 on autophagy

(2017) Ana Guedes et al.   MECHANISMS OF AGEING AND DEVELOPMENT

α-synuclein toxicity in neurodegeneration: mechanism and therapeutic strategies

(2017) Yvette C Wong et al.   NATURE MEDICINE

A pathway of targeted autophagy is induced by DNA damage in budding yeast

(2017) Vinay V. Eapen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The mechanism of sirtuin 2–mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease

(2017) Rita Machado de Oliveira et al.   PLOS BIOLOGY

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Role of the Cell Cycle Re-Initiation in DNA Damage Response of Post-Mitotic Cells and Its Implication in the Pathogenesis of Neurodegenerative Diseases

(2016) Paulina Tokarz et al.   REJUVENATION RESEARCH

Leveraging DNA Damage Response Signaling to Identify Yeast Genes Controlling Genome Stability

(2015) Jason A. Hendry et al.   G3-Genes Genomes Genetics

DJ-1 interactions with α-synuclein attenuate aggregation and cellular toxicity in models of Parkinson’s disease

(2014) L Zondler et al.   Cell Death & Disease

DNA replication stress-induced loss of reproductive capacity inS. cerevisiaeand its inhibition by caloric restriction

(2013) Martin Weinberger et al.   CELL CYCLE

SNCA (α-synuclein)-induced toxicity in yeast cells is dependent on Sir2-mediated mitophagy

(2012) Belém Sampaio-Marques et al.   Autophagy

Alpha-synuclein and Protein Degradation Systems: a Reciprocal Relationship

(2012) Maria Xilouri et al.   MOLECULAR NEUROBIOLOGY

Alpha-synuclein functions in the nucleus to protect against hydroxyurea-induced replication stress in yeast

(2011) Xianpeng Liu et al.   HUMAN MOLECULAR GENETICS

Autophagy-Dependent Regulation of the DNA Damage Response Protein Ribonucleotide Reductase 1

(2011) M. Dyavaiah et al.   MOLECULAR CANCER RESEARCH

Glucose tolerance status and risk of dementia in the community: The Hisayama Study

(2011) T. Ohara et al.   NEUROLOGY

Role of Cell Cycle Re-Entry in Neurons: A Common Apoptotic Mechanism of Neuronal Cell Death

(2011) Jaume Folch et al.   NEUROTOXICITY RESEARCH

Activation of ataxia telangiectasia muted under experimental models and human Parkinson’s disease

(2010) Antoni Camins et al.   CELLULAR AND MOLECULAR LIFE SCIENCES