DNA replication stress-induced loss of reproductive capacity inS. cerevisiaeand its inhibition by caloric restriction

Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density

(2016) Yong Pan et al.   Aging-US

Growth signaling promotes chronological aging in budding yeast by inducing superoxide anions that inhibit quiescence

(2016) Martin Weinberger et al.   Aging-US

Depletion of Deoxyribonucleotide Pools Is an Endogenous Source of DNA Damage in Cells Undergoing Oncogene-Induced Senescence

(2012) Sudha Mannava et al.   AMERICAN JOURNAL OF PATHOLOGY

pH neutralization protects against reduction in replicative lifespan following chronological aging in yeast

(2012) Christopher Murakami et al.   CELL CYCLE

Replicative and Chronological Aging in Saccharomyces cerevisiae

(2012) Valter D. Longo et al.   Cell Metabolism

Diabetes, cancer, and metformin: connections of metabolism and cell proliferation

(2011) Emily Jane Gallagher et al.   Annals of the New York Academy of Sciences

Nucleotide Deficiency Promotes Genomic Instability in Early Stages of Cancer Development

(2011) Assaf C. Bester et al.   CELL

Acetic acid effects on aging in budding yeast: Are they relevant to aging in higher eukaryotes?

(2011) William C. Burhans et al.   CELL CYCLE

Lsm1 promotes genomic stability by controlling histone mRNA decay

(2011) Ana B Herrero et al.   EMBO JOURNAL

Metabolic status rather than cell cycle signals control quiescence entry and exit

(2011) Damien Laporte et al.   JOURNAL OF CELL BIOLOGY

Compromised cellular responses to DNA damage accelerate chronological aging by incurring cell wall fragility in Saccharomyces cerevisiae

(2011) Shanshan Yu et al.   MOLECULAR BIOLOGY REPORTS

Nutrient Sensing Kinases PKA and Sch9 Phosphorylate the Catalytic Domain of the Ubiquitin-Conjugating Enzyme Cdc34

(2011) Ross Cocklin et al.   PLoS One

Okazaki fragment maturation: nucleases take centre stage

(2011) L. Zheng et al.   Journal of Molecular Cell Biology

Identification of evolutionarily conserved genetic regulators of cellular aging

(2010) Gerhard T. Laschober et al.   AGING CELL

A molecular mechanism of chronological aging in yeast

(2010) Christopher R. Burtner et al.   CELL CYCLE

Yeast lsm pro-apoptotic mutants show defects in S-phase entry and progression

(2010) Vanessa Palermo et al.   CELL CYCLE

Yeast as a model system to study RecQ helicase function

(2010) Thomas M. Ashton et al.   DNA REPAIR

MRC1-dependent scaling of the budding yeast DNA replication timing program

(2010) A. Koren et al.   GENOME RESEARCH

Mitochondrial redox metabolism: Aging, longevity and dietary effects

(2010) Melissa M. Page et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Genomic instability — an evolving hallmark of cancer

(2010) Simona Negrini et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Caloric restriction or catalase inactivation extends yeast chronological lifespan by inducing H2O2 and superoxide dismutase activity

(2010) A. Mesquita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

When a theory of aging ages badly

(2009) Jérôme Lapointe et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Elevated dNTP levels suppress hyper-recombination in Saccharomyces cerevisiae S-phase checkpoint mutants

(2009) Michael Fasullo et al.   NUCLEIC ACIDS RESEARCH

Glutamine Deprivation Induces Abortive S-Phase Rescued by Deoxyribonucleotides in K-Ras Transformed Fibroblasts

(2009) Daniela Gaglio et al.   PLoS One

Chronological aging-induced apoptosis in yeast

(2008) Paola Fabrizio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Longevity mutation inSCH9prevents recombination errors and premature genomic instability in a Werner/Bloom model system

(2008) Federica Madia et al.   JOURNAL OF CELL BIOLOGY

Characterization of Differentiated Quiescent and Nonquiescent Cells in Yeast Stationary-Phase Cultures

(2008) Anthony D. Aragon et al.   MOLECULAR BIOLOGY OF THE CELL

Mitochondrial dysfunction is a possible cause of accelerated senescence of mesothelial cells exposed to high glucose

(2007) Krzysztof Ksiazek et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS