Asymmetric Synthesis of Spirooxindoles with Seven Stereocenters via Organocatalyzed One‐pot Three‐component Sequential Cascade Reactions

Catalytic asymmetric synthesis of spirooxindoles: recent developments

(2018) Guang-Jian Mei et al.   CHEMICAL COMMUNICATIONS

Diastereo- and Enantioselective Dearomative [3 + 2] Cycloaddition Reaction of 2-Nitrobenzofurans with 3-Isothiocyanato Oxindoles

(2018) Jian-Qiang Zhao et al.   ORGANIC LETTERS

Organocatalytic Asymmetric [3 + 2] Cycloaddition of N-2,2,2-Trifluoroethylisatin Ketimines with β-Trifluoromethyl Electron-Deficient Alkenes: Access to Vicinally Bis(trifluoromethyl)-Substituted 3,2′-Pyrrolidinyl Spirooxindoles

(2018) Yong You et al.   ORGANIC LETTERS

Asymmetric synthesis of 3,3′-pyrrolidinyl-dispirooxindoles via a one-pot organocatalytic Mannich/deprotection/aza-Michael sequence

(2016) Kun Zhao et al.   CHEMICAL COMMUNICATIONS

Organocatalytic Asymmetric Michael/Cyclization Cascade Reaction of 3-Isothiocyanato Oxindoles with Maleimides for the Efficient Construction of Pyrrolidonyl Spirooxindoles

(2016) Lei Liu et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Recent Advances of α-Isothiocyanato Compounds in the Catalytic Asymmetric Reaction

(2015) Wen-Yong Han et al.   ADVANCED SYNTHESIS & CATALYSIS

The Squaramide-Catalyzed 1,3-Dipolar Cycloaddition of Nitroalkenes withN-2,2,2-Trifluoroethylisatin Ketimines: An Approach for the Synthesis of 5′-Trifluoromethyl-spiro[pyrrolidin-3,2′-oxindoles]

(2015) Quantao Sun et al.   ADVANCED SYNTHESIS & CATALYSIS

The asymmetric synthesis of CF3-containing spiro[pyrrolidin-3,2′-oxindole] through the organocatalytic 1,3-dipolar cycloaddition reaction

(2015) Mingxia Ma et al.   CHEMICAL COMMUNICATIONS

An Organocatalytic Michael–Michael Cascade for the Enantioselective Construction of Spirocyclopentane Bioxindoles: Control of Four Contiguous Stereocenters

(2014) Wangsheng Sun et al.   ORGANIC LETTERS

Catalytic C–C Bond-Forming Multi-Component Cascade or Domino Reactions: Pushing the Boundaries of Complexity in Asymmetric Organocatalysis

(2013) Chandra M. R. Volla et al.   CHEMICAL REVIEWS

Enantioselective Total Synthesis of (−)-Citrinadin A and Revision of Its Stereochemical Structure

(2013) Zhiguo Bian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and Antimicrobial and Antifungal Activity of Carbamate-Functionized Spiro Compounds

(2013) A. V. Velikorodov et al.   PHARMACEUTICAL CHEMISTRY JOURNAL

Development of Cascade Reactions for the Concise Construction of Diverse Heterocyclic Architectures

(2012) Liang-Qiu Lu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Catalytic Asymmetric Synthesis of Spirooxindoles by a Mannich-Type Reaction of Isothiocyanato Oxindoles

(2012) Shota Kato et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Isatins As Privileged Molecules in Design and Synthesis of Spiro-Fused Cyclic Frameworks

(2012) Girija S. Singh et al.   CHEMICAL REVIEWS

Recent advances in organocatalytic methods for the synthesis of disubstituted 2- and 3-indolinones

(2012) Renato Dalpozzo et al.   CHEMICAL SOCIETY REVIEWS

Applications of asymmetric organocatalysis in medicinal chemistry

(2012) José Alemán et al.   CHEMICAL SOCIETY REVIEWS

Brønsted-Acid-Catalyzed Asymmetric Multicomponent Reactions for the Facile Synthesis of Highly Enantioenriched Structurally Diverse Nitrogenous Heterocycles

(2011) Jie Yu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Highly Enantioselective [3+2] Annulation of Morita-Baylis-Hillman Adducts Mediated by L-Threonine-Derived Phosphines: Synthesis of 3-Spirocyclopentene-2-oxindoles having Two Contiguous Quaternary Centers

(2011) Fangrui Zhong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Construction of bispirooxindoles containing three quaternary stereocentres in a cascade using a single multifunctional organocatalyst

(2011) Bin Tan et al.   Nature Chemistry

Organocatalytic Direct Asymmetric Aldol Reactions of 3-Isothiocyanato Oxindoles to Ketones: Stereocontrolled Synthesis of Spirooxindoles Bearing Highly Congested Contiguous Tetrasubstituted Stereocenters

(2011) Wen-Bing Chen et al.   ORGANIC LETTERS

Organocatalytic cascade reactions as a new tool in total synthesis

(2010) Christoph Grondal et al.   Nature Chemistry

Natural Product Synthesis Using Multicomponent Reaction Strategies

(2009) Barry B. Touré et al.   CHEMICAL REVIEWS

The art of total synthesis through cascade reactions

(2009) K. C. Nicolaou et al.   CHEMICAL SOCIETY REVIEWS

Synthesis of novel spiropyrrolizidines as potent antimicrobial agents for human and plant pathogens

(2008) Govindasami Periyasami et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS