Leptin stimulates autophagy/lysosome-related degradation of long-lived proteins in adipocytes

TP53 is required for BECN1- and ATG5-dependent cell death induced by sphingosine kinase 1 inhibition

(2018) Santiago Lima et al.   Autophagy

Leptin promotes pulmonary fibrosis development by inhibiting autophagy via PI3K/Akt/mTOR pathway

(2018) Xianhua Gui et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nutrient excess and autophagic deficiency: explaining metabolic diseases in obesity

(2018) Gustav van Niekerk et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Targeting autophagy in obesity: from pathophysiology to management

(2018) Yingmei Zhang et al.   Nature Reviews Endocrinology

Up-regulated autophagy: as a protective factor in adipose tissue of WOKW rats with metabolic syndrome

(2018) J. Kosacka et al.   Diabetology & Metabolic Syndrome

Adipose tissue autophagy related gene expression is associated with glucometabolic status in human obesity

(2018) Qing Xu et al.   Adipocyte

Estrogen receptor signaling mediates leptin-induced growth of breast cancer cells via autophagy induction

(2017) Pawan Kumar Raut et al.   Oncotarget

Reduced Endoplasmic Reticulum Stress-Mediated Autophagy Is Required for Leptin Alleviating Inflammation in Adipose Tissue

(2017) Lu Gan et al.   Frontiers in Immunology

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Decreased adiponectin links elevated adipose tissue autophagy with adipocyte endocrine dysfunction in obesity

(2016) N Slutsky et al.   INTERNATIONAL JOURNAL OF OBESITY

Hyperactivation of the Insulin Signaling Pathway Improves Intracellular Proteostasis by Coordinately Up-regulating the Proteostatic Machinery in Adipocytes

(2016) Annabel Y. Minard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptional Dysregulation of Adipose Tissue Autophagy in Obesity

(2016) Nitzan Maixner et al.   PHYSIOLOGY

Elevated autophagy gene expression in adipose tissue of obese humans: A potential non-cell-cycle-dependent function of E2F1

(2015) Yulia Haim et al.   Autophagy

DAPK2 Downregulation Associates With Attenuated Adipocyte Autophagic Clearance in Human Obesity

(2015) Hedi Soussi et al.   DIABETES

Autophagy in adipose tissue of patients with obesity and type 2 diabetes

(2015) J. Kosacka et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis

(2015) Susmita Kaushik et al.   NATURE CELL BIOLOGY

Restriction on an Energy-Dense Diet Improves Markers of Metabolic Health and Cellular Aging in Mice Through Decreasing Hepatic mTOR Activity

(2015) Anke Schloesser et al.   REJUVENATION RESEARCH

Autophagy induction by leptin contributes to suppression of apoptosis in cancer cells and xenograft model: Involvement of p53/FoxO3A axis

(2015) Saroj Nepal et al.   Oncotarget

The reciprocal interaction between autophagic dysfunction and ER stress in adipose insulin resistance

(2014) Huixia Li et al.   CELL CYCLE

Autophagy in adipose tissue and the beta cell: implications for obesity and diabetes

(2014) Rinke Stienstra et al.   DIABETOLOGIA

Inhibition of Autophagic Turnover in β-Cells by Fatty Acids and Glucose Leads to Apoptotic Cell Death

(2014) Shakeel U. R. Mir et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Leptin modulates autophagy in human CD4+CD25− conventional T cells

(2014) Silvana Cassano et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Chaperone-mediated autophagy: roles in disease and aging

(2013) Ana Maria Cuervo et al.   CELL RESEARCH

Defective regulation of adipose tissue autophagy in obesity

(2013) C E Nuñez et al.   INTERNATIONAL JOURNAL OF OBESITY

The return of the nucleus: transcriptional and epigenetic control of autophagy

(2013) Jens Füllgrabe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Autophagy in Human Health and Disease

(2013) Augustine M.K. Choi et al.   NEW ENGLAND JOURNAL OF MEDICINE

A novel image-based cytometry method for autophagy detection in living cells

(2012) Leo Li-Ying Chan et al.   Autophagy

Autophagy Activity Is Up-Regulated in Adipose Tissue of Obese Individuals and Modulates Proinflammatory Cytokine Expression

(2012) H. J. Jansen et al.   ENDOCRINOLOGY

Autophagy in Adipose Tissue

(2012) Nitzan Maixner et al.   Obesity Facts

Autophagy regulates inflammation in adipocytes

(2011) Takeshi Yoshizaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Neuroendocrine regulation of autophagy by leptin

(2011) Shoaib Ahmad Malik et al.   CELL CYCLE

Pancreatic cancers require autophagy for tumor growth

(2011) S. Yang et al.   GENES & DEVELOPMENT

Fatty Acids Suppress Autophagic Turnover in β-Cells

(2011) Guy Las et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Altered Autophagy in Human Adipose Tissues in Obesity

(2010) Julia Kovsan et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Unknown

(2010) Anita Ost et al.   MOLECULAR MEDICINE

Depot-specific adipocyte cell lines reveal differential drug-induced responses of white adipocytes—relevance for partial lipodystrophy

(2008) Julia Kovsan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Egr-1 Regulates Autophagy in Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease

(2008) Zhi-Hua Chen et al.   PLoS One